HERB: a high-throughput experiment- and reference-guided database of traditional Chinese medicine

Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker

(2020) Miquel Duran-Frigola et al.   NATURE BIOTECHNOLOGY

TCMIO: A Comprehensive Database of Traditional Chinese Medicine on Immuno-Oncology

(2020) Zhihong Liu et al.   Frontiers in Pharmacology

CNIT: a fast and accurate web tool for identifying protein-coding and long non-coding transcripts based on intrinsic sequence composition

(2019) Jin-Cheng Guo et al.   NUCLEIC ACIDS RESEARCH

In silico drug repositioning: from large-scale transcriptome data to therapeutics

(2019) Ok-Seon Kwon et al.   ARCHIVES OF PHARMACAL RESEARCH

Exploring the molecular mechanisms of Traditional Chinese Medicine components using gene expression signatures and connectivity map

(2018) Minjae Yoo et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Trends in the global immuno-oncology landscape

(2018) Jun Tang et al.   NATURE REVIEWS DRUG DISCOVERY

SymMap: an integrative database of traditional Chinese medicine enhanced by symptom mapping

(2018) Yang Wu et al.   NUCLEIC ACIDS RESEARCH

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

PubChem 2019 update: improved access to chemical data

(2018) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

The Gene Ontology Resource: 20 years and still GOing strong

(2018)   NUCLEIC ACIDS RESEARCH

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources

(2018) Sebastian Köhler et al.   NUCLEIC ACIDS RESEARCH

Effective cancer immunotherapy by Ganoderma lucidum polysaccharide-gold nanocomposites through dendritic cell activation and memory T cell response

(2018) Shulei Zhang et al.   CARBOHYDRATE POLYMERS

TCMID 2.0: a comprehensive resource for TCM

(2017) Lin Huang et al.   NUCLEIC ACIDS RESEARCH

NONCODEV5: a comprehensive annotation database for long non-coding RNAs

(2017) ShuangSang Fang et al.   NUCLEIC ACIDS RESEARCH

DrugBank 5.0: a major update to the DrugBank database for 2018

(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

The gene expression profiles in response to 102 traditional Chinese medicine (TCM) components: a general template for research on TCMs

(2017) Chao Lv et al.   Scientific Reports

Deubiquitination and Stabilization of PD-L1 by CSN5

(2016) Seung-Oe Lim et al.   CANCER CELL

Withaferin A is a leptin sensitizer with strong antidiabetic properties in mice

(2016) Jaemin Lee et al.   NATURE MEDICINE

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

(2016) H Jin et al.   Cell Death & Disease

Treatment of Obesity with Celastrol

(2015) Junli Liu et al.   CELL

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

(2015) Jens U. Marquardt et al.   JOURNAL OF HEPATOLOGY

Modulation of the tumor microenvironment and inhibition of EGF/EGFR pathway: Novel anti-tumor mechanisms of Cannabidiol in breast cancer

(2015) Mohamad Elbaz et al.   Molecular Oncology

The re-emergence of natural products for drug discovery in the genomics era

(2015) Alan L. Harvey et al.   NATURE REVIEWS DRUG DISCOVERY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Systematic integration of RNA-Seq statistical algorithms for accurate detection of differential gene expression patterns

(2014) Panagiotis Moulos et al.   NUCLEIC ACIDS RESEARCH

Mitochondrial inhibitor sensitizes non-small-cell lung carcinoma cells to TRAIL-induced apoptosis by reactive oxygen species and Bcl-XL/p53-mediated amplification mechanisms

(2014) Y-L Shi et al.   Cell Death & Disease

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Resveratrol improves intrahepatic endothelial dysfunction and reduces hepatic fibrosis and portal pressure in cirrhotic rats

(2012) Marco Di Pascoli et al.   JOURNAL OF HEPATOLOGY

Melatonin enhances thapsigargin-induced apoptosis through reactive oxygen species-mediated upregulation of CCAAT-enhancer-binding protein homologous protein in human renal cancer cells

(2012) Kyoung-jin Min et al.   JOURNAL OF PINEAL RESEARCH

Landmark article: A pharmacognostic and chemical study of ma huang (Ephedra vulgaris var. Helvetica)

(2012)   JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION

TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis

(2012) Ruichao Xue et al.   NUCLEIC ACIDS RESEARCH

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

The discovery of artemisinin (qinghaosu) and gifts from Chinese medicine

(2011) Youyou Tu   NATURE MEDICINE

ncFANs: a web server for functional annotation of long non-coding RNAs

(2011) Q. Liao et al.   NUCLEIC ACIDS RESEARCH

Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network

(2011) Qi Liao et al.   NUCLEIC ACIDS RESEARCH

Disease Ontology: a backbone for disease semantic integration

(2011) L. M. Schriml et al.   NUCLEIC ACIDS RESEARCH

A framework for oligonucleotide microarray preprocessing

(2010) Benilton S. Carvalho et al.   BIOINFORMATICS

HIT: linking herbal active ingredients to targets

(2010) H. Ye et al.   NUCLEIC ACIDS RESEARCH

Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation

(2006) X Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY