NOPCHAP1 is a PAQosome cofactor that helps loading NOP58 on RUVBL1/2 during box C/D snoRNP biogenesis

CB-6644 is a selective inhibitor of the RUVBL1/2 complex with anti-cancer activity

(2019) Victoria A Assimon et al.   ACS Chemical Biology

Bcd1p controls RNA loading of the core protein Nop58 during C/D box snoRNP biogenesis

(2019) Arnaud Paul et al.   RNA

Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM

(2019) Hugo Muñoz-Hernández et al.   Science Advances

The Hsp70 chaperone network

(2019) Rina Rosenzweig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Yeast R2TP Interacts with Extended Termini of Client Protein Nop58p

(2019) Ge Yu et al.   Scientific Reports

Modifications in small nuclear RNAs and their roles in spliceosome assembly and function

(2018) Markus T. Bohnsack et al.   BIOLOGICAL CHEMISTRY

Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex

(2018) Julien Henri et al.   STRUCTURE

The PAQosome, an R2TP-Based Chaperone for Quaternary Structure Formation

(2018) Walid A. Houry et al.   TRENDS IN BIOCHEMICAL SCIENCES

The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones

(2018) Chloé Maurizy et al.   Nature Communications

Revisions to the Classification, Nomenclature, and Diversity of Eukaryotes

(2018) Sina M. Adl et al.   JOURNAL OF EUKARYOTIC MICROBIOLOGY

Structural basis for ATP-dependent chromatin remodelling by the INO80 complex

(2018) Sebastian Eustermann et al.   NATURE

Structure and regulation of the human INO80–nucleosome complex

(2018) Rafael Ayala et al.   NATURE

Author Correction: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

(2018) Fabrizio Martino et al.   Nature Communications

The Hsp70–Hsp90 Chaperone Cascade in Protein Folding

(2018) Tania Morán Luengo et al.   TRENDS IN CELL BIOLOGY

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones

(2017) Anna Malinová et al.   JOURNAL OF CELL BIOLOGY

Eukaryotic ribosome assembly, transport and quality control

(2017) Cohue Peña et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pih1p-Tah1p Puts a Lid on Hexameric AAA+ ATPases Rvb1/2p

(2017) Shaoxiong Tian et al.   STRUCTURE

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein

(2017) Philippe Cloutier et al.   Nature Communications

Eukaryotic ribosome assembly, transport and quality control

(2017) Cohue Peña et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

smiFISH and FISH-quant – a flexible single RNA detection approach with super-resolution capability

(2016) Nikolay Tsanov et al.   NUCLEIC ACIDS RESEARCH

Tuning the ribosome: The influence of rRNA modification on eukaryotic ribosome biogenesis and function

(2016) Katherine E. Sloan et al.   RNA Biology

Assembly and trafficking of box C/D and H/ACA snoRNPs

(2016) Séverine Massenet et al.   RNA Biology

Architecture of the yeast small subunit processome

(2016) Malik Chaker-Margot et al.   SCIENCE

A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting

(2016) Katjana Tantale et al.   Nature Communications

Reconstitution of the human U snRNP assembly machinery reveals stepwise Sm protein organization

(2015) N. Neuenkirchen et al.   EMBO JOURNAL

Yeast Rvb1 and Rvb2 Proteins Oligomerize As a Conformationally Variable Dodecamer with Low Frequency

(2015) Ajitha Jeganathan et al.   JOURNAL OF MOLECULAR BIOLOGY

Hsp90: Breaking the Symmetry

(2015) Matthias P. Mayer et al.   MOLECULAR CELL

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Noncoding RNAs in eukaryotic ribosome biogenesis and function

(2015) Denis L J Lafontaine   NATURE STRUCTURAL & MOLECULAR BIOLOGY

NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins

(2015) Jonathan Bizarro et al.   NUCLEIC ACIDS RESEARCH

Noncoding RNAs in eukaryotic ribosome biogenesis and function

(2015) Denis L J Lafontaine   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SnoRNPs, ZNHIT proteins and the R2TP pathway

(2015) Céline Verheggen et al.   Oncotarget

Glucocorticoid Receptor Function Regulated by Coordinated Action of the Hsp90 and Hsp70 Chaperone Cycles

(2014) Elaine Kirschke et al.   CELL

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control

(2014) Jonathan Bizarro et al.   JOURNAL OF CELL BIOLOGY

A day in the life of the spliceosome

(2014) A. Gregory Matera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein Hit1, a novel box C/D snoRNP assembly factor, controls cellular concentration of the scaffolding protein Rsa1 by direct interaction

(2014) Benjamin Rothé et al.   NUCLEIC ACIDS RESEARCH

Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

(2014) Mohinder Pal et al.   STRUCTURE

Lytic Water Dynamics Reveal Evolutionarily Conserved Mechanisms of ATP Hydrolysis by TIP49 AAA+ ATPases

(2014) Arina Afanasyeva et al.   STRUCTURE

Phosphorylation-Dependent PIH1D1 Interactions Define Substrate Specificity of the R2TP Cochaperone Complex

(2014) Zuzana Hořejší et al.   Cell Reports

Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex

(2013) Alessandro Tosi et al.   CELL

High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex

(2013) Régis Back et al.   STRUCTURE

CRM1 controls the composition of nucleoplasmic pre-snoRNA complexes to licence them for nucleolar transport

(2011) Bérengère Pradet-Balade et al.   EMBO JOURNAL

The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic

(2011) H. Walbott et al.   GENES & DEVELOPMENT

Subunit Organization of the Human INO80 Chromatin Remodeling Complex

(2011) Lu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for site-specific ribose methylation by box C/D RNA protein complexes

(2011) Jinzhong Lin et al.   NATURE

The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA

(2011) Nicholas J. Watkins et al.   Wiley Interdisciplinary Reviews-RNA

The Spatial-Functional Coupling of Box C/D and C'/D' RNPs Is an Evolutionarily Conserved Feature of the Eukaryotic Box C/D snoRNP Nucleotide Modification Complex

(2010) G. Qu et al.   MOLECULAR AND CELLULAR BIOLOGY

Evidence that the AAA+ Proteins TIP48 and TIP49 Bridge Interactions between 15.5K and the Related NOP56 and NOP58 Proteins during Box C/D snoRNP Biogenesis

(2009) K. S. McKeegan et al.   MOLECULAR AND CELLULAR BIOLOGY

The Hsp90 chaperone controls the biogenesis of L7Ae RNPs through conserved machinery

(2008) Séverine Boulon et al.   JOURNAL OF CELL BIOLOGY

Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation

(2008) Rongmin Zhao et al.   JOURNAL OF CELL BIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY

Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics

(2008) M. E. Sardiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically Disordered Proteins Display No Preference for Chaperone Binding In Vivo

(2008) Hedi Hegyi et al.   PLoS Computational Biology