Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation

Complement-dependent synapse loss and microgliosis in a mouse model of multiple sclerosis

(2020) Jennetta W. Hammond et al.   BRAIN BEHAVIOR AND IMMUNITY

Motor learning promotes remyelination via new and surviving oligodendrocytes

(2020) Clara M. Bacmeister et al.   NATURE NEUROSCIENCE

CSF1R signaling is a regulator of pathogenesis in progressive MS

(2020) Nellwyn Hagan et al.   Cell Death & Disease

Fibrinogen Induces Microglia-Mediated Spine Elimination and Cognitive Impairment in an Alzheimer’s Disease Model

(2019) Mario Merlini et al.   NEURON

Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis

(2019) Maarten E. Witte et al.   NEURON

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration

(2019) Dmitri Lodygin et al.   NATURE

In vivo imaging reveals reduced activity of neuronal circuits in a mouse tauopathy model

(2019) Petar Marinković et al.   BRAIN

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

Synaptic alterations and immune response are sexually dimorphic in a non-pertussis toxin model of experimental autoimmune encephalomyelitis

(2019) Kayla L. Murphy et al.   EXPERIMENTAL NEUROLOGY

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

(2019) Sebastian Werneburg et al.   IMMUNITY

Deep gray matter volume loss drives disability worsening in multiple sclerosis

(2018) Arman Eshaghi et al.   ANNALS OF NEUROLOGY

Inflammatory intrathecal profiles and cortical damage in multiple sclerosis

(2018) Roberta Magliozzi et al.   ANNALS OF NEUROLOGY

Csf1R inhibition attenuates experimental autoimmune encephalomyelitis and promotes recovery

(2018) Jillian C. Nissen et al.   EXPERIMENTAL NEUROLOGY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

The cortical damage, early relapses, and onset of the progressive phase in multiple sclerosis

(2018) Antonio Scalfari et al.   NEUROLOGY

Multiple Sclerosis

(2018) Daniel S. Reich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neurons under T Cell Attack Coordinate Phagocyte-Mediated Synaptic Stripping

(2018) Giovanni Di Liberto et al.   CELL

Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis

(2018) Erik Ellwardt et al.   NATURE NEUROSCIENCE

Alterations in CA1 hippocampal synapses in a mouse model of fragile X syndrome

(2017) Safdar Jawaid et al.   GLIA

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

Phosphatidylserine Exposure Controls Viral Innate Immune Responses by Microglia

(2017) Yusuf Tufail et al.   NEURON

Hippocampal and Deep Gray Matter Nuclei Atrophy Is Relevant for Explaining Cognitive Impairment in MS: A Multicenter Study

(2016) D. Damjanovic et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology

(2016) Adrian Olmos-Alonso et al.   BRAIN

Microglia: Phagocytosing to Clear, Sculpt, and Eliminate

(2016) Soyon Hong et al.   DEVELOPMENTAL CELL

A complement–microglial axis drives synapse loss during virus-induced memory impairment

(2016) Michael J. Vasek et al.   NATURE

Cell-specific restoration of stimulus preference after monocular deprivation in the visual cortex

(2016) T. Rose et al.   SCIENCE

Complement C1q-C3-associated synaptic changes in multiple sclerosis hippocampus

(2015) Iliana Michailidou et al.   ANNALS OF NEUROLOGY

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis

(2015) Tanja Jürgens et al.   BRAIN

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(2015) Don H Mahad et al.   LANCET NEUROLOGY

Pathway-specific reorganization of projection neurons in somatosensory cortex during learning

(2015) Jerry L Chen et al.   NATURE NEUROSCIENCE

Spatial and Working Memory Is Linked to Spine Density and Mushroom Spines

(2015) Rasha Refaat Mahmmoud et al.   PLoS One

Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

(2014) Nicolas Snaidero et al.   CELL

Differential roles of microglia and monocytes in the inflamed central nervous system

(2014) Ryo Yamasaki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Label-free in vivo imaging of myelinated axons in health and disease with spectral confocal reflectance microscopy

(2014) Aaron J Schain et al.   NATURE MEDICINE

Optimized ratiometric calcium sensors for functional in vivo imaging of neurons and T lymphocytes

(2014) Thomas Thestrup et al.   NATURE METHODS

Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

(2014) Zuzana Šišková et al.   NEURON

Thy1-GCaMP6 Transgenic Mice for Neuronal Population Imaging In Vivo

(2014) Hod Dana et al.   PLoS One

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

(2013) Christopher Gardner et al.   BRAIN

NMDA Receptor Activation and Calpain Contribute to Disruption of Dendritic Spines by the Stress Neuropeptide CRH

(2013) Adrienne L. Andres et al.   JOURNAL OF NEUROSCIENCE

Cortical lesion load associates with progression of disability in multiple sclerosis

(2012) M. Calabrese et al.   BRAIN

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Inflammatory Cortical Demyelination in Early Multiple Sclerosis

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Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

(2010) Ranjan Dutta et al.   ANNALS OF NEUROLOGY

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

Fast Nonnegative Deconvolution for Spike Train Inference From Population Calcium Imaging

(2010) Joshua T. Vogelstein et al.   JOURNAL OF NEUROPHYSIOLOGY

Default-mode network dysfunction and cognitive impairment in progressive MS

(2010) M. A. Rocca et al.   NEUROLOGY

Rapid formation and selective stabilization of synapses for enduring motor memories

(2009) Tonghui Xu et al.   NATURE

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE