Nanomaterials to relieve tumor hypoxia for enhanced photodynamic therapy

Hybrid Nanospheres to Overcome Hypoxia and Intrinsic Oxidative Resistance for Enhanced Photodynamic Therapy

(2020) Leilei Shi et al.   ACS Nano

Self-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor

(2020) Dongdong Wang et al.   Nature Communications

Enhanced Ferroptosis by Oxygen-Boosted Phototherapy Based on a 2-in-1 Nanoplatform of Ferrous Hemoglobin for Tumor Synergistic Therapy

(2020) Tian Xu et al.   ACS Nano

Carbon Nitride Hollow Theranostic Nanoregulators Executing Laser-Activatable Water Splitting for Enhanced Ultrasound/Fluorescence Imaging and Cooperative Phototherapy

(2020) Xing Zhang et al.   ACS Nano

An open source and reduce expenditure ROS generation strategy for chemodynamic/photodynamic synergistic therapy

(2020) Conghui Liu et al.   Nature Communications

Cyanobacteria-Based Bio-Oxygen Pump Promoting Hypoxia-Resistant Photodynamic Therapy

(2020) Tao Sun et al.   Frontiers in Bioengineering and Biotechnology

Recent advances in photonanomedicines for enhanced cancer photodynamic therapy

(2020) Jing-Jing Hu et al.   PROGRESS IN MATERIALS SCIENCE

Molecular landmarks of tumor hypoxia across cancer types

(2019) Vinayak Bhandari et al.   NATURE GENETICS

Carbon-dot-supported atomically dispersed gold as a mitochondrial oxidative stress amplifier for cancer treatment

(2019) Ningqiang Gong et al.   Nature Nanotechnology

Hypoxia alleviation-triggered enhanced photodynamic therapy in combination with IDO inhibitor for preferable cancer therapy

(2019) Lei Xing et al.   BIOMATERIALS

Protein Shell-Encapsulated Pt Clusters as Continuous O2-Supplied Biocoats for Photodynamic Therapy in Hypoxic Cancer Cells

(2019) Yahang Li et al.   ACS Applied Materials & Interfaces

A hybrid nanomaterial with NIR-induced heat and associated hydroxyl radical generation for synergistic tumor therapy

(2019) Cheng Zhang et al.   BIOMATERIALS

A Smart Photosensitizer–Cerium Oxide Nanoprobe for Highly Selective and Efficient Photodynamic Therapy

(2019) Yifan Fan et al.   INORGANIC CHEMISTRY

Tumor Reoxygenation and Blood Perfusion Enhanced Photodynamic Therapy using Ultrathin Graphdiyne Oxide Nanosheets

(2019) Yucai Wang et al.   NANO LETTERS

Annexin A2 Regulates AKT Upon H2O2-Dependent Signaling Activation in Cancer Cells

(2019) Stéphanie Castaldo et al.   Cancers

Fenton reaction assisted photodynamic therapy for cancer with multifunctional magnetic nanoparticles

(2019) Huabo Hou et al.   ACS Applied Materials & Interfaces

Surface-Doped Graphitic Carbon Nitride Catalyzed Photooxidation of Olefins and Dienes: Chemical Evidence for Electron Transfer and Singlet Oxygen Mechanisms

(2019) Apostolos Chatzoudis et al.   Catalysts

Light triggered oxygen-affording engines for repeated hypoxia-resistant photodynamic therapy

(2019) Tian-Jiao Zhou et al.   JOURNAL OF CONTROLLED RELEASE

Nanozymes-Engineered Metal–Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy

(2019) Chuang Liu et al.   NANO LETTERS

Inorganic Nanozyme with Combined Self-Oxygenation/Degradable Capabilities for Sensitized Cancer Immunochemotherapy

(2019) Jie Wang et al.   Nano-Micro Letters

Sensitization of Hypoxic Tumor to Photodynamic Therapy via Oxygen Self-Supply of Fluorinated Photosensitizers

(2019) Zhiyong Liu et al.   BIOMACROMOLECULES

Recent Progress and Approaches on Carbon-Free Energy from Water Splitting

(2019) Aslam Hossain et al.   Nano-Micro Letters

All-in-One Theranostic Nanoagent with Enhanced Reactive Oxygen Species Generation and Modulating Tumor Microenvironment Ability for Effective Tumor Eradication

(2018) Yang Liu et al.   ACS Nano

Bacteria-Driven Hypoxia Targeting for Combined Biotherapy and Photothermal Therapy

(2018) Wenfei Chen et al.   ACS Nano

Normalizing Tumor Microenvironment Based on Photosynthetic Abiotic/Biotic Nanoparticles

(2018) Diwei Zheng et al.   ACS Nano

Organic Semiconducting Photoacoustic Nanodroplets for Laser-Activatable Ultrasound Imaging and Combinational Cancer Therapy

(2018) Wei Tang et al.   ACS Nano

Nanozyme Decorated Metal–Organic Frameworks for Enhanced Photodynamic Therapy

(2018) Yan Zhang et al.   ACS Nano

Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect

(2018) Zhikuan Chen et al.   ACS Nano

Semiconducting Polymer Nanoenzymes with Photothermic Activity for Enhanced Cancer Therapy

(2018) Jingchao Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic O 2 -Evolving metal-organic framework nanoplatform for highly efficient photodynamic therapy against hypoxic tumor

(2018) Shutao Gao et al.   BIOMATERIALS

Photodynamic therapy in hypoxia: Near-infrared-sensitive, self-supported, oxygen generation nano-platform enabled by upconverting nanoparticles

(2018) Na Niu et al.   CHEMICAL ENGINEERING JOURNAL

Catalytic chemistry of glucose oxidase in cancer diagnosis and treatment

(2018) Lian-Hua Fu et al.   CHEMICAL SOCIETY REVIEWS

Synchronous delivery of oxygen and photosensitizer for alleviation of hypoxia tumor microenvironment and dramatically enhanced photodynamic therapy

(2018) Xiaomeng Guo et al.   DRUG DELIVERY

Photoelectrochemical water splitting: an idea heading towards obsolescence?

(2018) T. Jesper Jacobsson   Energy & Environmental Science

Direct observation of noble metal nanoparticles transforming to thermally stable single atoms

(2018) Shengjie Wei et al.   Nature Nanotechnology

Nanobubble-embedded inorganic 808 nm excited upconversion nanocomposites for tumor multiple imaging and treatment

(2018) Ming-Hsien Chan et al.   Chemical Science

Optically-controlled bacterial metabolite for cancer therapy

(2018) Di-Wei Zheng et al.   Nature Communications

Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor

(2018) Shuting Xu et al.   Nature Communications

Computer-aided discovery of a metal–organic framework with superior oxygen uptake

(2018) Peyman Z. Moghadam et al.   Nature Communications

O2-generating MnO2 nanoparticles for enhanced photodynamic therapy of bladder cancer by ameliorating hypoxia

(2018) Tingsheng Lin et al.   Theranostics

Cell-penetrating peptide-based nanovehicles potentiate lymph metastasis targeting and deep penetration for anti-metastasis therapy

(2018) Haiyan Hu et al.   Theranostics

Tumor-targeted hybrid protein oxygen carrier to simultaneously enhance hypoxia-dampened chemotherapy and photodynamic therapy at a single dose

(2018) Zhenyu Luo et al.   Theranostics

Oxygen self-sufficient fluorinated polypeptide nanoparticles for NIR imaging-guided enhanced photodynamic therapy

(2018) Pan Yuan et al.   Journal of Materials Chemistry B

Heterogeneous single-atom catalysis

(2018) Aiqin Wang et al.   Nature Reviews Chemistry

Modulating Hypoxia via Nanomaterials Chemistry for Efficient Treatment of Solid Tumors

(2018) Yanyan Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bacteria photosensitized by intracellular gold nanoclusters for solar fuel production

(2018) Hao Zhang et al.   Nature Nanotechnology

Biomimetic nanoflowers by self-assembly of nanozymes to induce intracellular oxidative damage against hypoxic tumors

(2018) Zhenzhen Wang et al.   Nature Communications

Cover Picture: Discovery of Elusive K4 O6 , a Compound Stabilized by Configurational Entropy of Polarons (Angew. Chem. Int. Ed. 1/2019)

(2018) Christoph Freysoldt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

O2-Loaded pH-Responsive Multifunctional Nanodrug Carrier for Overcoming Hypoxia and Highly Efficient Chemo-Photodynamic Cancer Therapy

(2018) Zhongxi Xie et al.   CHEMISTRY OF MATERIALS

Overcoming tumor hypoxia as a barrier to radiotherapy, chemotherapy and immunotherapy in cancer treatment

(2018) Kaitlin Graham et al.   International Journal of Nanomedicine

Near-Infrared Light-Initiated Molecular Superoxide Radical Generator: Rejuvenating Photodynamic Therapy against Hypoxic Tumors

(2018) Mingle Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A two-photon excited O2-evolving nanocomposite for efficient photodynamic therapy against hypoxic tumor

(2018) Run-Qing Li et al.   BIOMATERIALS

A Facile Ion-Doping Strategy To Regulate Tumor Microenvironments for Enhanced Multimodal Tumor Theranostics

(2017) Jing Bai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Continuous O2-Evolving MnFe2O4 Nanoparticle-Anchored Mesoporous Silica Nanoparticles for Efficient Photodynamic Therapy in Hypoxic Cancer

(2017) Jonghoon Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Singlet Oxygen-Engaged Selective Photo-Oxidation over Pt Nanocrystals/Porphyrinic MOF: The Roles of Photothermal Effect and Pt Electronic State

(2017) Yu-Zhen Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photocatalytic oxygen evolution from low-bandgap conjugated microporous polymer nanosheets: a combined first-principles calculation and experimental study

(2017) Lei Wang et al.   Nanoscale

Targeting microbial biofilms: current and prospective therapeutic strategies

(2017) Hyun Koo et al.   NATURE REVIEWS MICROBIOLOGY

Fluorinated polymer–photosensitizer conjugates enable improved generation of ROS for anticancer photodynamic therapy

(2017) Jaqueline D. Wallat et al.   Polymer Chemistry

NIR-driven water splitting by layered bismuth oxyhalide sheets for effective photodynamic therapy

(2017) Dan Yang et al.   Journal of Materials Chemistry B

Recent Progress in Energy-Driven Water Splitting

(2017) Si Yin Tee et al.   Advanced Science

Carbon-Dot-Decorated Carbon Nitride Nanoparticles for Enhanced Photodynamic Therapy against Hypoxic Tumor via Water Splitting

(2016) Di-Wei Zheng et al.   ACS Nano

Emerging Multifunctional Metal-Organic Framework Materials

(2016) Bin Li et al.   ADVANCED MATERIALS

Remote-Controlled Release of Singlet Oxygen by the Plasmonic Heating of Endoperoxide-Modified Gold Nanorods: Towards a Paradigm Change in Photodynamic Therapy

(2016) Safacan Kolemen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Photocontrol of Peptidomimetics: An Alternative to Oxygen-Dependent Photodynamic Cancer Therapy

(2016) Oleg Babii et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-Harvesting and Amplified Energy Transfer in Conjugated Polymer Nanoparticles

(2016) Yifei Jiang et al.   CHEMICAL REVIEWS

Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy

(2016) Zijian Zhou et al.   CHEMICAL SOCIETY REVIEWS

An Implantable Depot That Can Generate Oxygen in Situ for Overcoming Hypoxia-Induced Resistance to Anticancer Drugs in Chemotherapy

(2016) Chieh-Cheng Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ultrasound Triggered Tumor Oxygenation with Oxygen-Shuttle Nanoperfluorocarbon to Overcome Hypoxia-Associated Resistance in Cancer Therapies

(2016) Xuejiao Song et al.   NANO LETTERS

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

(2016) Bernard Thienpont et al.   NATURE

The ever-expanding role of HIF in tumour and stromal biology

(2016) Edward L. LaGory et al.   NATURE CELL BIOLOGY

Magneto-aerotactic bacteria deliver drug-containing nanoliposomes to tumour hypoxic regions

(2016) Ouajdi Felfoul et al.   Nature Nanotechnology

Poly(trimethylene carbonate)-based polymers engineered for biodegradable functional biomaterials

(2016) K. Fukushima   Biomaterials Science

Fabrication of dendrimer-releasing lipidic nanoassembly for cancer drug delivery

(2016) Qihang Sun et al.   Biomaterials Science

Hemoglobin-Based Nanoarchitectonic Assemblies as Oxygen Carriers

(2015) Yi Jia et al.   ADVANCED MATERIALS

Synthesis of Hemoglobin Conjugated Polymeric Micelle: A ZnPc Carrier with Oxygen Self-Compensating Ability for Photodynamic Therapy

(2015) Shasha Wang et al.   BIOMACROMOLECULES

Hypoxia and hypoxia inducible factors in tumor metabolism

(2015) Wen Zeng et al.   CANCER LETTERS

Nanoparticles in Photodynamic Therapy

(2015) Sasidharan Swarnalatha Lucky et al.   CHEMICAL REVIEWS

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

(2015) Janusz M. Dąbrowski et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Biology of Hypoxia

(2015) Paul N. Span et al.   SEMINARS IN NUCLEAR MEDICINE

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

(2015) Yuhao Cheng et al.   Nature Communications

Developments in PDT Sensitizers for Increased Selectivity and Singlet Oxygen Production

(2015) Nahid Mehraban et al.   Materials

Multifunctional Albumin–MnO2 Nanoparticles Modulate Solid Tumor Microenvironment by Attenuating Hypoxia, Acidosis, Vascular Endothelial Growth Factor and Enhance Radiation Response

(2014) Preethy Prasad et al.   ACS Nano

Metal-Organic Frameworks for Oxygen Storage

(2014) Jared B. DeCoste et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Graphdiyne and graphyne: from theoretical predictions to practical construction

(2014) Yongjun Li et al.   CHEMICAL SOCIETY REVIEWS

Ultrasensitive Nanosensors Based on Upconversion Nanoparticles for Selective Hypoxia Imaging in Vivo upon Near-Infrared Excitation

(2014) Jianan Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible Light-Driven Pure Water Splitting by a Nature-Inspired Organic Semiconductor-Based System

(2014) David James Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mesoporous silica nanorods intrinsically doped with photosensitizers as a multifunctional drug carrier for combination therapy of cancer

(2014) Guangbao Yang et al.   Nano Research

Semiconducting polymer nanoparticles as photoacoustic molecular imaging probes in living mice

(2014) Kanyi Pu et al.   Nature Nanotechnology

Graphene-Based Materials for Hydrogen Generation from Light-Driven Water Splitting

(2013) Guancai Xie et al.   ADVANCED MATERIALS

Perfluorocarbon Nanoparticles for Physiological and Molecular Imaging and Therapy

(2013) Junjie Chen et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Oxygen-releasing biomaterials for tissue engineering

(2013) Gulden Camci-Unal et al.   POLYMER INTERNATIONAL

Root Effect Hemoglobin May Have Evolved to Enhance General Tissue Oxygen Delivery

(2013) J. L. Rummer et al.   SCIENCE

CD24 Is an Effector of HIF-1-Driven Primary Tumor Growth and Metastasis

(2012) S. Thomas et al.   CANCER RESEARCH

Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials

(2012) E. Pedraza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer/Hemoglobin Assemblies: Biodegradable Oxygen Carriers for Artificial Red Blood Cells

(2011) Taihang Li et al.   MACROMOLECULAR BIOSCIENCE

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology