Genomic instability as a main driving factor of unsuccessful ageing: Potential for translating the use of micronuclei into clinical practice

Cytotoxic and genotoxic effects in mechanics occupationally exposed to diesel engine exhaust

(2019) Grethel León-Mejía et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Nuclear Genomic Instability and Aging

(2018) Laura J. Niedernhofer et al.   Annual Review of Biochemistry

Cytokinesis-block micronucleus cytome assay parameters in peripheral blood lymphocytes of the general population: Contribution of age, sex, seasonal variations and lifestyle factors

(2018) Goran Gajski et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Frailty Syndrome and Genomic Instability in Older Adults: Suitability of the Cytome Micronucleus Assay As a Diagnostic Tool

(2018) María Sánchez-Flores et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Effects of age and gender on the baseline and 2 Gy 60 Co γ-ray-induced nucleoplasmic bridges frequencies in the peripheral blood lymphocytes of Chinese population

(2018) Tian-Jing Cai et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

DNA damage and circulating cell free DNA in greenhouse workers exposed to pesticides

(2017) Akin Çayir et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Genome instability: a conserved mechanism of ageing?

(2017) Jan Vijg et al.   Essays in Biochemistry

Genomic health status assessed by a cytokinesis-block micronucleus cytome assay in a healthy middle-aged Korean population

(2017) Nan Young Cho et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Frailty measurement in research and clinical practice: A review

(2016) Elsa Dent et al.   European Journal of Internal Medicine

Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults

(2016) Javier Angulo et al.   MOLECULAR ASPECTS OF MEDICINE

DNA, the central molecule of aging

(2016) Peter Lenart et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Molecular mechanisms by which in vivo exposure to exogenous chemical genotoxic agents can lead to micronucleus formation in lymphocytes in vivo and ex vivo in humans

(2016) Michael Fenech et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Cognitive frailty, a novel target for the prevention of elderly dependency

(2015) Qingwei Ruan et al.   AGEING RESEARCH REVIEWS

Increased micronucleus, nucleoplasmic bridge, nuclear bud frequency and oxidative DNA damage associated with prolactin levels and pituitary adenoma diameters in patients with prolactinoma

(2015) N Bitgen et al.   BIOTECHNIC & HISTOCHEMISTRY

Age-related frailty and its association with biological markers of ageing

(2015) Arnold Mitnitski et al.   BMC Medicine

Accelerating aging research: How can we measure the rate of biologic aging?

(2015) Joseph B. Margolick et al.   EXPERIMENTAL GERONTOLOGY

Micronucleus frequency in peripheral blood lymphocytes and frailty status in elderly. A lack of association with clinical features

(2015) Vanessa Valdiglesias et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Clinical application of micronucleus test in exfoliated buccal cells: A systematic review and metanalysis

(2015) Claudia Bolognesi et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Geroscience: Linking Aging to Chronic Disease

(2014) Brian K. Kennedy et al.   CELL

Chromosomal DNA damage measured using the cytokinesis-block micronucleus cytome assay is significantly associated with cognitive impairment in South Australians

(2014) Sau Lai Lee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Mechanisms underlying mutational signatures in human cancers

(2014) Thomas Helleday et al.   NATURE REVIEWS GENETICS

DNA Damage in Buccal Mucosa Cells of Pre-School Children Exposed to High Levels of Urban Air Pollutants

(2014) Elisabetta Ceretti et al.   PLoS One

Association between endothelial dysfunction and frailty: the Toledo Study for Healthy Aging

(2013) Cristina Alonso-Bouzón et al.   AGE

Genome Instability and Aging

(2013) Jan Vijg et al.   Annual Review of Physiology

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

DNA repair mechanisms in dividing and non-dividing cells

(2013) Teruaki Iyama et al.   DNA REPAIR

The effect of age, sex, and lifestyle factors on micronucleus frequency in peripheral blood lymphocytes of the Bosnian population

(2013) Hilada Nefic et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Evaluation of background DNA damage in a Turkish population measured by means of the cytokinesis-block micronucleus cytome assay

(2013) Mahmut Coşkun et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Aging and reprogramming: a two-way street

(2012) Salah Mahmoudi et al.   CURRENT OPINION IN CELL BIOLOGY

Investigation of Genome Instability in Exfoliated Colonic Epithelial Cells and in Mitogen-Stimulated Lymphocytes of Patients with Ulcerative Colitis

(2012) Ahmet Karaman et al.   DIGESTION

Frailty Transitions in the San Antonio Longitudinal Study of Aging

(2012) Sara E. Espinoza et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Evaluation of the genotoxicity and cytotoxicity in the general population in Turkey by use of the cytokinesis-block micronucleus cytome assay

(2012) Hamiyet Donmez-Altuntas et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The rate of human mutation

(2012) Alexey Kondrashov   NATURE

Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan

(2012) Darren J. Baker et al.   NATURE CELL BIOLOGY

Measuring Genome Instability in Aging – A Mini-Review

(2011) Wenge Li et al.   GERONTOLOGY

A mouse model of accelerated liver aging caused by a defect in DNA repair

(2011) Siobhán Q. Gregg et al.   HEPATOLOGY

Genotoxicity biomarkers in occupational exposure to formaldehyde—The case of histopathology laboratories

(2011) Carina Ladeira et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Genomic instability and cancer: an introduction

(2011) Z. Shen   Journal of Molecular Cell Biology

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes

(2010) M. Fenech et al.   MUTAGENESIS

Cytokinesis-blocked micronucleus cytome and comet assays in peripheral blood lymphocytes of workers exposed to lead considering folate and vitamin B12 status

(2010) Renato Minozzo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Buccal micronucleus frequency is associated with age in Down syndrome

(2009) F.L.S. Ferreira et al.   GENETICS AND MOLECULAR RESEARCH

Frailty Syndrome: A Transitional State in a Dynamic Process

(2009) Pierre-Olivier Lang et al.   GERONTOLOGY

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

(2009) Matilde Murga et al.   NATURE GENETICS

DNA double-strand breaks: A potential causative factor for mammalian aging?

(2008) Han Li et al.   MECHANISMS OF AGEING AND DEVELOPMENT