Effects of mexiletine on hyperexcitability in sporadic amyotrophic lateral sclerosis: Preliminary findings from a small phase II randomized controlled trial

Cortical hyperexcitability evolves with disease progression in ALS

(2020) Parvathi Menon et al.   Annals of Clinical and Translational Neurology

Functional Biomarkers for Amyotrophic Lateral Sclerosis

(2019) William Huynh et al.   Frontiers in Neurology

Mexiletine for muscle cramps in amyotrophic lateral sclerosis: A randomized, double-blind crossover trial

(2018) Björn Oskarsson et al.   MUSCLE & NERVE

Test–retest reliability of single and paired pulse transcranial magnetic stimulation parameters in healthy subjects

(2016) A.M. Hermsen et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cortical hyperexcitability in patients withC9ORF72mutations: Relationship to phenotype

(2016) Olivia Schanz et al.   MUSCLE & NERVE

Motor cortical function determines prognosis in sporadic ALS

(2016) Kazumoto Shibuya et al.   NEUROLOGY

A randomized trial of mexiletine in ALS

(2016) Michael D. Weiss et al.   NEUROLOGY

Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis

(2016) Yuta Iwai et al.   PLoS One

Cortical hyperexcitability precedes lower motor neuron dysfunction in ALS

(2015) Parvathi Menon et al.   CLINICAL NEUROPHYSIOLOGY

Cortical excitability changes distinguish the motor neuron disease phenotypes from hereditary spastic paraplegia

(2015) N. Geevasinga et al.   EUROPEAN JOURNAL OF NEUROLOGY

Sensitivity and specificity of threshold tracking transcranial magnetic stimulation for diagnosis of amyotrophic lateral sclerosis: a prospective study

(2015) Parvathi Menon et al.   LANCET NEUROLOGY

A single blind randomized controlled clinical trial of mexiletine in amyotrophic lateral sclerosis: Efficacy and safety of sodium channel blocker phase II trial

(2015) Kazumoto Shibuya et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Cortical Function in Asymptomatic Carriers and Patients WithC9orf72Amyotrophic Lateral Sclerosis

(2015) Nimeshan Geevasinga et al.   JAMA Neurology

Axonal Ion Channel Dysfunction inC9orf72Familial Amyotrophic Lateral Sclerosis

(2015) Nimeshan Geevasinga et al.   JAMA Neurology

Navigated transcranial magnetic stimulation in amyotrophic lateral sclerosis

(2014) Alexander V. Chervyakov et al.   MUSCLE & NERVE

A Computational Model of Motor Neuron Degeneration

(2014) Gwendal Le Masson et al.   NEURON

Cortical Dysfunction Underlies the Development of the Split-Hand in Amyotrophic Lateral Sclerosis

(2014) Parvathi Menon et al.   PLoS One

Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons

(2014) Brian J. Wainger et al.   Cell Reports

The Puzzling Case of Hyperexcitability in Amyotrophic Lateral Sclerosis

(2013) Jong Seok Bae et al.   Journal of Clinical Neurology

Split hand syndrome in amyotrophic lateral sclerosis: different excitability changes in the thenar and hypothenar motor axons

(2013) K. Shibuya et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mutant SOD1-expressing astrocytes release toxic factors that trigger motoneuron death by inducing hyperexcitability

(2013) Elsa Fritz et al.   JOURNAL OF NEUROPHYSIOLOGY

Excitability and the safety margin in human axons during hyperthermia

(2013) James Howells et al.   JOURNAL OF PHYSIOLOGY-LONDON

Motor axonal excitability properties are strong predictors for survival in amyotrophic lateral sclerosis

(2012) Kazuaki Kanai et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Transcranial magnetic stimulation and amyotrophic lateral sclerosis: pathophysiological insights

(2012) Steve Vucic et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cortical excitability distinguishes ALS from mimic disorders

(2011) Steve Vucic et al.   CLINICAL NEUROPHYSIOLOGY

Efficacy Loss of the Anticonvulsant Carbamazepine in Mice Lacking Sodium Channel   Subunits via Paradoxical Effects on Persistent Sodium Currents

(2010) M. Uebachs et al.   JOURNAL OF NEUROSCIENCE

Upregulation of persistent sodium conductances in familial ALS

(2009) S. Vucic et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis

(2008) Steve Vucic et al.   BRAIN

State of the art: Pharmacologic effects on cortical excitability measures tested by transcranial magnetic stimulation

(2008) Walter Paulus et al.   Brain Stimulation

Axonal excitability in the forearm: Normal data and differences along the median nerve

(2008) S.K. Jankelowitz et al.   CLINICAL NEUROPHYSIOLOGY