Axonal Dysfunction Precedes Motor Neuronal Death in Amyotrophic Lateral Sclerosis

Fasciculation discharge frequency in amyotrophic lateral sclerosis and related disorders

(2016) Mamede de Carvalho et al.   CLINICAL NEUROPHYSIOLOGY

Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability

(2015) Anna-Claire Devlin et al.   Nature Communications

A single blind randomized controlled clinical trial of mexiletine in amyotrophic lateral sclerosis: Efficacy and safety of sodium channel blocker phase II trial

(2015) Kazumoto Shibuya et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Curcumin abolishes mutant TDP-43 induced excitability in a motoneuron-like cellular model of ALS

(2014) H. Dong et al.   NEUROSCIENCE

Intrinsic Membrane Hyperexcitability of Amyotrophic Lateral Sclerosis Patient-Derived Motor Neurons

(2014) Brian J. Wainger et al.   Cell Reports

Fasciculations, axonal hyperecitability, and motoneuronal death in amyotrophic lateral sclerosis

(2013) Satoshi Kuwabara et al.   CLINICAL NEUROPHYSIOLOGY

Spreading of amyotrophic lateral sclerosis lesions--multifocal hits and local propagation?

(2013) T. Sekiguchi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Split hand syndrome in amyotrophic lateral sclerosis: different excitability changes in the thenar and hypothenar motor axons

(2013) K. Shibuya et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Progressive axonal dysfunction and clinical impairment in amyotrophic lateral sclerosis

(2012) Benjamin C. Cheah et al.   CLINICAL NEUROPHYSIOLOGY

Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?

(2012) Tadashi Kanouchi et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Neurophysiological index as a biomarker for ALS progression: Validity of mixed effects models

(2011) Benjamin C. Cheah et al.   Amyotrophic Lateral Sclerosis

Markedly reduced axonal potassium channel expression in human sporadic amyotrophic lateral sclerosis: An immunohistochemical study

(2011) Kazumoto Shibuya et al.   EXPERIMENTAL NEUROLOGY

Propagation: Prion-like mechanisms can explain spreading of motor neuronal death in amyotrophic lateral sclerosis?

(2011) S. Kuwabara et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Nerve excitability studies characterize KV1.1 fast potassium channel dysfunction in patients with episodic ataxia type 1

(2010) Susan E. Tomlinson et al.   BRAIN

Riluzole, Neuroprotection and Amyotrophic Lateral Sclerosis

(2010) B.C. Cheah et al.   CURRENT MEDICINAL CHEMISTRY

Voltage gated potassium channel antibodies in amyotrophic lateral sclerosis

(2009) Victoria K. Nwosu et al.   Amyotrophic Lateral Sclerosis

Axonal ion channels from bench to bedside: A translational neuroscience perspective

(2009) Arun V. Krishnan et al.   PROGRESS IN NEUROBIOLOGY