Developmental impaired Akt signaling in the Shank1 and Shank3 double knock-out mice

Arc protein: a flexible hub for synaptic plasticity and cognition

(2018) Oleksii Nikolaienko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease

(2018) Julia R. Wilkerson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cotinine Reduces Amyloid-β Aggregation and Improves Memory in Alzheimer's Disease Mice

(2018) Valentina Echeverria et al.   JOURNAL OF ALZHEIMERS DISEASE

Aberrant cognitive phenotypes and altered hippocampal BDNF expression related to epigenetic modifications in mice lacking the post-synaptic scaffolding protein SHANK1: Implications for autism spectrum disorder

(2017) A. Özge Sungur et al.   HIPPOCAMPUS

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function

(2016) Thomas C. Jaramillo et al.   Autism Research

Cotinine administration improves impaired cognition in the mouse model of Fragile X syndrome

(2016) Marta Pardo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

(2016) C Vicidomini et al.   MOLECULAR PSYCHIATRY

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency

(2016) Michael Bidinosti et al.   SCIENCE

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

(2016) Xiaoming Wang et al.   Nature Communications

Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders

(2015) Carlo Sala et al.   JOURNAL OF NEUROCHEMISTRY

Pharmacokinetics of cotinine in rats: A potential therapeutic agent for disorders of cognitive function

(2015) Pei Li et al.   Pharmacological Reports

Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function

(2015) Anne Biever et al.   Frontiers in Molecular Neuroscience

Cotinine reduces depressive-like behavior, working memory deficits, and synaptic loss associated with chronic stress in mice

(2014) J. Alex Grizzell et al.   BEHAVIOURAL BRAIN RESEARCH

γ-band abnormalities as markers of autism spectrum disorders

(2014) Donald C Rojas et al.   Biomarkers in Medicine

Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer’s disease

(2014) Jie Gao et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Repetitive behaviors in the Shank1 knockout mouse model for autism spectrum disorder: Developmental aspects and effects of social context

(2014) A. Özge Sungur et al.   JOURNAL OF NEUROSCIENCE METHODS

Ultrasonic vocalizations in Shank mouse models for autism spectrum disorders: Detailed spectrographic analyses and developmental profiles

(2014) Markus Wöhr   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Cotinine halts the advance of Alzheimer's disease-like pathology and associated depressive-like behavior in Tg6799 mice

(2014) Sagar Patel et al.   Frontiers in Aging Neuroscience

Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments

(2014) Claire S. Leblond et al.   PLoS Genetics

Rescue of cAMP Response Element-Binding Protein Signaling Reversed Spatial Memory Retention Impairments Induced by Subanesthetic Dose of Propofol

(2013) Hao Zhang et al.   CNS Neuroscience & Therapeutics

Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

(2013) M. Kouser et al.   JOURNAL OF NEUROSCIENCE

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats

(2012) Alvin V. Terry et al.   BIOCHEMICAL PHARMACOLOGY

Cotinine: A Potential New Therapeutic Agent against Alzheimer's disease

(2012) Valentina Echeverria et al.   CNS Neuroscience & Therapeutics

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption

(2012) Valentina Echeverria Moran   Frontiers in Pharmacology

Pharmacologic Rescue of Impaired Cognitive Flexibility, Social Deficits, Increased Aggression, and Seizure Susceptibility in Oxytocin Receptor Null Mice: A Neurobehavioral Model of Autism

(2011) Mariaelvina Sala et al.   BIOLOGICAL PSYCHIATRY

Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

(2011) Andreas M Grabrucker et al.   EMBO JOURNAL

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Communication Impairments in Mice Lacking Shank1: Reduced Levels of Ultrasonic Vocalizations and Scent Marking Behavior

(2011) Markus Wöhr et al.   PLoS One

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Arc in synaptic plasticity: from gene to behavior

(2011) Erica Korb et al.   TRENDS IN NEUROSCIENCES

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

Sociability and motor functions in Shank1 mutant mice

(2010) Jill L. Silverman et al.   BRAIN RESEARCH

Synaptic Activity Controls Dendritic Spine Morphology by Modulating eEF2-Dependent BDNF Synthesis

(2010) C. Verpelli et al.   JOURNAL OF NEUROSCIENCE

The Postsynaptic Density Proteins Homer and Shank Form a Polymeric Network Structure

(2009) Mariko Kato Hayashi et al.   CELL

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

(2008) A. Y. Hung et al.   JOURNAL OF NEUROSCIENCE

Extensive early motor and non-motor behavioral deficits are followed by striatal neuronal loss in knock-in Huntington's disease mice

(2008) M.A. Hickey et al.   NEUROSCIENCE

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR