Constitutive activation of integrin αvβ3 contributes to anoikis resistance of ovarian cancer cells

The survivin molecule as a double-edged sword in cellular physiologic and pathologic conditions and its role as a potential biomarker and therapeutic target in cancer

(2019) Atieh Rafatmanesh et al.   JOURNAL OF CELLULAR PHYSIOLOGY

14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling

(2018) Jing Luo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

(2018) Soon-Ki Hong et al.   Molecular Cancer

Exploring the Role of RGD-Recognizing Integrins in Cancer

(2017) Markus Nieberler et al.   Cancers

β3 integrin promotes chemoresistance to epirubicin in MDA-MB-231 through repression of the pro-apoptotic protein, BAD

(2016) Madhumathy G. Nair et al.   EXPERIMENTAL CELL RESEARCH

The BCL-2 protein family, BH3-mimetics and cancer therapy

(2015) A R D Delbridge et al.   CELL DEATH AND DIFFERENTIATION

Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors

(2015) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Anoikis molecular pathways and its role in cancer progression

(2013) Paolo Paoli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A bioengineered 3D ovarian cancer model for the assessment of peptidase–mediated enhancement of spheroid growth and intraperitoneal spread

(2013) Daniela Loessner et al.   BIOMATERIALS

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

The Glycophorin A Transmembrane Sequence within Integrin αvβ3 Creates a Non-Signaling Integrin with Low Basal Affinity That Is Strongly Adhesive under Force

(2013) Martina A. Müller et al.   JOURNAL OF MOLECULAR BIOLOGY

Differences in growth properties of endometrial cancer in three dimensional (3D) culture and 2D cell monolayer

(2012) Kenny Chitcholtan et al.   EXPERIMENTAL CELL RESEARCH

Anoikis: an emerging hallmark in health and diseases

(2011) ML Taddei et al.   JOURNAL OF PATHOLOGY

The proliferation rate paradox in antimitotic chemotherapy

(2011) Timothy J. Mitchison   MOLECULAR BIOLOGY OF THE CELL

The tail of integrin activation

(2011) Nicholas J. Anthis et al.   TRENDS IN BIOCHEMICAL SCIENCES

Live Free or Die

(2010) Craig Horbinski et al.   AMERICAN JOURNAL OF PATHOLOGY

ErbB2 Stabilizes Epidermal Growth Factor Receptor (EGFR) Expression via Erk and Sprouty2 in Extracellular Matrix-detached Cells

(2010) Alexandra R. Grassian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Transmembrane Structure of Integrin αIIbβ3: Significance for Signal Transduction

(2009) Martin Hoefling et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model

(2009) Anis Feki et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling

(2009) Tong-Lay Lau et al.   EMBO JOURNAL

Epidermal growth factor receptor in relation to tumor development: EGFR gene and cancer

(2009) Tetsuya Mitsudomi et al.   FEBS Journal

Multicellular spheroids in ovarian cancer metastases: Biology and pathology

(2009) Kristy Shield et al.   GYNECOLOGIC ONCOLOGY

An integrin αvβ3–c-Src oncogenic unit promotes anchorage-independence and tumor progression

(2009) Jay S Desgrosellier et al.   NATURE MEDICINE

Anoikis: A necessary death program for anchorage-dependent cells

(2008) Paola Chiarugi et al.   BIOCHEMICAL PHARMACOLOGY

Anoikis resistance and tumor metastasis

(2008) Craig D. Simpson et al.   CANCER LETTERS

Integrin αvβ3 mediates upregulation of epidermal growth-factor receptor expression and activity in human ovarian cancer cells

(2008) Daniela Lössner et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

 v 3 Integrin-Mediated Drug Resistance in Human Laryngeal Carcinoma Cells Is Caused by Glutathione-Dependent Elimination of Drug-Induced Reactive Oxidative Species

(2008) A. Brozovic et al.   MOLECULAR PHARMACOLOGY

Regulation of angiogenesis: apoptotic cues from the ECM

(2008) D A Cheresh et al.   ONCOGENE

Transmembrane signal transduction of the αIIbβ3 integrin

(2002) Kay E. Gottschalk et al.   PROTEIN SCIENCE