Vesicle Tethering on the Surface of Phase-Separated Active Zone Condensates

Phase separation organizes the site of autophagosome formation

(2020) Yuko Fujioka et al.   NATURE

Phase separation at the synapse

(2020) Xudong Chen et al.   NATURE NEUROSCIENCE

Vesicle Clustering in a Living Synapse Depends on a Synapsin Region that Mediates Phase Separation

(2020) Arndt Pechstein et al.   Cell Reports

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses

(2020) Alessandra Sclip et al.   eLife

Assembly of the presynaptic active zone

(2020) Javier Emperador-Melero et al.   CURRENT OPINION IN NEUROBIOLOGY

Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates

(2020) Yan G. Zhao et al.   DEVELOPMENTAL CELL

Liquid-Liquid Phase Separation in Neuronal Development and Synaptic Signaling

(2020) Xiandeng Wu et al.   DEVELOPMENTAL CELL

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry

(2020) Richard G. Held et al.   NEURON

ELKS1 Captures Rab6-Marked Vesicular Cargo in Presynaptic Nerve Terminals

(2020) Hajnalka Nyitrai et al.   Cell Reports

RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation

(2019) Xiandeng Wu et al.   MOLECULAR CELL

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

Phase Separation-Mediated TARP/MAGUK Complex Condensation and AMPA Receptor Synaptic Transmission

(2019) Menglong Zeng et al.   NEURON

The ERC1 scaffold protein implicated in cell motility drives the assembly of a liquid phase

(2019) Kristyna Sala et al.   Scientific Reports

RIM C 2 B Domains Target Presynaptic Active Zone Functions to PIP 2 -Containing Membranes

(2018) Arthur P.H. de Jong et al.   NEURON

Liprin-α3 controls vesicle docking and exocytosis at the active zone of hippocampal synapses

(2018) Man Yan Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A liquid phase of synapsin and lipid vesicles

(2018) Dragomir Milovanovic et al.   SCIENCE

ELKS active zone proteins as multitasking scaffolds for secretion

(2018) Richard G. Held et al.   Open Biology

Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity

(2018) Menglong Zeng et al.   CELL

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

Synaptic weight set by Munc13-1 supramolecular assemblies

(2017) Hirokazu Sakamoto et al.   NATURE NEUROSCIENCE

Transcellular Nanoalignment of Synaptic Function

(2017) Thomas Biederer et al.   NEURON

Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function

(2017) Oleg O. Glebov et al.   Cell Reports

Production of Isolated Giant Unilamellar Vesicles under High Salt Concentrations

(2017) Hannah Stein et al.   Frontiers in Physiology

Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity

(2016) Menglong Zeng et al.   CELL

A trans-synaptic nanocolumn aligns neurotransmitter release to receptors

(2016) Ai-Hui Tang et al.   NATURE

How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs

(2016) Claudio Acuna et al.   NEURON

Fusion Competent Synaptic Vesicles Persist upon Active Zone Disruption and Loss of Vesicle Docking

(2016) Shan Shan H. Wang et al.   NEURON

Functions of Rab Proteins at Presynaptic Sites

(2016) Beyenech Binotti et al.   Cells

Presynaptic active zones in invertebrates and vertebrates

(2015) F. Ackermann et al.   EMBO REPORTS

The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones

(2014) Cordelia Imig et al.   NEURON

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Rapid Fusion of Synaptic Vesicles with Reconstituted Target SNARE Membranes

(2013) Volker Kiessling et al.   BIOPHYSICAL JOURNAL

Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle

(2013) Thomas C. Südhof   NEURON

LAR-RPTPs: synaptic adhesion molecules that shape synapse development

(2013) Ji Won Um et al.   TRENDS IN CELL BIOLOGY

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

Release probability of hippocampal glutamatergic terminals scales with the size of the active zone

(2012) Noemi Holderith et al.   NATURE NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Synaptic Vesicle Pools and Dynamics

(2012) A. A. Alabi et al.   Cold Spring Harbor Perspectives in Biology

RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction

(2011) Pascal S. Kaeser et al.   CELL

Calcium Channels Link the Muscle-Derived Synapse Organizer Laminin  2 to Bassoon and CAST/Erc2 to Organize Presynaptic Active Zones

(2011) J. Chen et al.   JOURNAL OF NEUROSCIENCE

Protein scaffolds in the coupling of synaptic exocytosis and endocytosis

(2011) Volker Haucke et al.   NATURE REVIEWS NEUROSCIENCE

RIM Determines Ca2+ Channel Density and Vesicle Docking at the Presynaptic Active Zone

(2011) Yunyun Han et al.   NEURON

Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site

(2011) C. Limbach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

(2011) K. S. Y. Liu et al.   SCIENCE

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON

Vesicle Docking in Regulated Exocytosis

(2008) Matthijs Verhage et al.   TRAFFIC