Single-strand DNA breaks cause replisome disassembly

BRCA1 Mutational Complementation Induces Synthetic Viability

(2020) Joseph Nacson et al.   MOLECULAR CELL

The Histone Chaperone FACT Induces Cas9 Multi-turnover Behavior and Modifies Genome Manipulation in Human Cells

(2020) Alan S. Wang et al.   MOLECULAR CELL

The DNA replication fork suppresses CMG unloading from chromatin before termination

(2020) Emily Low et al.   GENES & DEVELOPMENT

CMG helicase disassembly is controlled by replication fork DNA, replisome components and a ubiquitin threshold

(2020) Tom D Deegan et al.   eLife

Replisome bypass of a protein-based R-loop block by Pif1

(2020) Grant D. Schauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal Resection Takes Place during Break-Induced Replication Repair of Collapsed Replication Forks and Is Controlled by Strand Invasion

(2019) Kristoffer P. Jakobsen et al.   Cell Reports

Replication Fork Activation Is Enabled by a Single-Stranded DNA Gate in CMG Helicase

(2019) Michael R. Wasserman et al.   CELL

TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

(2019) Remi Sonneville et al.   eLife

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

(2018) Justin L. Sparks et al.   CELL

CRL2Lrr1promotes unloading of the vertebrate replisome from chromatin during replication termination

(2017) James M. Dewar et al.   GENES & DEVELOPMENT

Acute inactivation of the replicative helicase in human cells triggers MCM8–9-dependent DNA synthesis

(2017) Toyoaki Natsume et al.   GENES & DEVELOPMENT

Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase

(2017) Lance Langston et al.   eLife

Break-induced telomere synthesis underlies alternative telomere maintenance

(2016) Robert L. Dilley et al.   NATURE

Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage

(2016) F. Jiang et al.   SCIENCE

The mechanism of DNA replication termination in vertebrates

(2015) James M. Dewar et al.   NATURE

Mus81 and converging forks limit the mutagenicity of replication fork breakage

(2015) R. Mayle et al.   SCIENCE

Repair of a DNA-Protein Crosslink by Replication-Coupled Proteolysis

(2014) Julien P. Duxin et al.   CELL

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

(2014) Samuel H. Sternberg et al.   NATURE

Pif1 helicase and Polδ promote recombination-coupled DNA synthesis via bubble migration

(2013) Marenda A. Wilson et al.   NATURE

Structural basis for processive DNA synthesis by yeast DNA polymerase ɛ

(2013) Matthew Hogg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A general approach to break the concentration barrier in single-molecule imaging

(2012) Anna B Loveland et al.   NATURE METHODS

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase   in rolling circle DNA synthesis

(2012) Y.-H. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

(2011) Yu V. Fu et al.   CELL

RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks

(2011) Yoshitami Hashimoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly

(2010) J. R. Lydeard et al.   GENES & DEVELOPMENT

Metadata matters: access to image data in the real world

(2010) Melissa Linkert et al.   JOURNAL OF CELL BIOLOGY

A Flp-nick system to study repair of a single protein-bound nick in vivo

(2009) Ida Nielsen et al.   NATURE METHODS

Robust single-particle tracking in live-cell time-lapse sequences

(2008) Khuloud Jaqaman et al.   NATURE METHODS

Single-strand break repair and genetic disease

(2008) Keith W. Caldecott   NATURE REVIEWS GENETICS

Efficient subpixel image registration algorithms

(2008) Manuel Guizar-Sicairos et al.   OPTICS LETTERS