The Smc5/6 Core Complex Is a Structure-Specific DNA Binding and Compacting Machine

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism

(2020) Byung-Gil Lee et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

(2020) Pilar Gutierrez-Escribano et al.   MOLECULAR CELL

A folded conformation of MukBEF and cohesin

(2019) Frank Bürmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

(2019) John F Marko et al.   NUCLEIC ACIDS RESEARCH

R Loops: From Physiological to Pathological Roles

(2019) Tatiana García-Muse et al.   CELL

Organization of Chromosomal DNA by SMC Complexes

(2019) Stanislau Yatskevich et al.   Annual Review of Genetics

The Smc5/6 Complex: New and Old Functions of the Enigmatic Long-Distance Relative

(2018) Luis Aragón   Annual Review of Genetics

Are SMC Complexes Loop Extruding Factors? Linking Theory With Fact

(2018) Jonathan Baxter et al.   BIOESSAYS

CLMSVault: A Software Suite for Protein Cross-Linking Mass-Spectrometry Data Analysis and Visualization

(2017) Mathieu Courcelles et al.   JOURNAL OF PROTEOME RESEARCH

Tuned SMC Arms Drive Chromosomal Loading of Prokaryotic Condensin

(2017) Frank Bürmann et al.   MOLECULAR CELL

Specialized interfaces of Smc5/6 control hinge stability and DNA association

(2017) Aaron Alt et al.   Nature Communications

The Smc5/6 complex regulates the yeast Mph1 helicase at RNA-DNA hybrid-mediated DNA damage

(2017) Juan Lafuente-Barquero et al.   PLoS Genetics

Oligomerization and ATP stimulate condensin-mediated DNA compaction

(2017) Ross A. Keenholtz et al.   Scientific Reports

Basis of Protein Stabilization by K Glutamate: Unfavorable Interactions with Carbon, Oxygen Groups

(2016) Xian Cheng et al.   BIOPHYSICAL JOURNAL

Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease

(2016) Saskia N. van der Crabben et al.   JOURNAL OF CLINICAL INVESTIGATION

Exploring Quantitative Yeast Phenomics with Single-Cell Analysis of DNA Damage Foci

(2016) Erin B. Styles et al.   Cell Systems

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

(2016) Joseph A. Newman et al.   PLoS One

A high-sensitivity phospho-switch triggered by Cdk1 governs chromosome morphogenesis during cell division

(2015) Xavier Robellet et al.   GENES & DEVELOPMENT

Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA

(2015) Katerina Zabrady et al.   NUCLEIC ACIDS RESEARCH

Kite Proteins: a Superfamily of SMC/Kleisin Partners Conserved Across Bacteria, Archaea, and Eukaryotes

(2015) Jan J. Palecek et al.   STRUCTURE

The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains

(2015) Marc-André Roy et al.   Scientific Reports

The Smc5/6 Complex Is an ATP-Dependent Intermolecular DNA Linker

(2015) Takaharu Kanno et al.   Cell Reports

Efficient initial volume determination from electron microscopy images of single particles

(2014) Javier Vargas et al.   BIOINFORMATICS

The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement

(2014) Kristian Jeppsson et al.   PLoS Genetics

The SMC1-SMC3 cohesin heterodimer structures DNA through supercoiling-dependent loop formation

(2013) Mingxuan Sun et al.   NUCLEIC ACIDS RESEARCH

SUMO ligase activity of vertebrate Mms21/Nse2 is required for efficient DNA repair but not for Smc5/6 complex stability

(2012) Maciej Kliszczak et al.   DNA REPAIR

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

DNA-binding properties of Smc6, a core component of the Smc5–6 DNA repair complex

(2011) Marc-André Roy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SMC5 and MMS21 are required for chromosome cohesion and mitotic progression

(2011) Susanne Behlke-Steinert et al.   CELL CYCLE

Dynamic and selective DNA-binding activity of Smc5, a core component of the Smc5-Smc6 complex

(2011) Marc-André Roy et al.   CELL CYCLE

Cohesin loading and sliding

(2011) M. T. Ocampo-Hafalla et al.   JOURNAL OF CELL SCIENCE

Chromosome length influences replication-induced topological stress

(2011) Andreas Kegel et al.   NATURE

A clustering approach to multireference alignment of single-particle projections in electron microscopy

(2010) C.O.S. Sorzano et al.   JOURNAL OF STRUCTURAL BIOLOGY

MAGE-RING Protein Complexes Comprise a Family of E3 Ubiquitin Ligases

(2010) Jennifer M. Doyle et al.   MOLECULAR CELL

Smc5/6 maintains stalled replication forks in a recombination-competent conformation

(2009) Anja Irmisch et al.   EMBO JOURNAL

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Polo Kinase Regulates Mitotic Chromosome Condensation by Hyperactivation of Condensin DNA Supercoiling Activity

(2009) Julie St-Pierre et al.   MOLECULAR CELL

Interplay between the Smc5/6 complex and the Mph1 helicase in recombinational repair

(2009) Yu-Hung Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA