Mitochondrial NAD+ Controls Nuclear ARTD1-Induced ADP-Ribosylation

SLC25A51 is a mammalian mitochondrial NAD+ transporter

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Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins

(2020) Kathrin Nowak et al.   Nature Communications

Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation

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MCART1/SLC25A51 is required for mitochondrial NAD transport

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Keeping the balance in NAD metabolism

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A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy

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Quantitative Analysis of NAD Synthesis-Breakdown Fluxes

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Synthetic α- and β-Ser-ADP-ribosylated Peptides Reveal α-Ser-ADPr as the Native Epimer

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Metabolic regulation of transcription through compartmentalized NAD+biosynthesis

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Analysis of PARP inhibitor toxicity by multidimensional fluorescence microscopy reveals mechanisms of sensitivity and resistance

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Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides

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Nicotinamide adenine dinucleotide is transported into mammalian mitochondria

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NAD Kinases: Metabolic Targets Controlling Redox Co-enzymes and Reducing Power Partitioning in Plant Stress and Development

(2018) Bin-Bin Li et al.   Frontiers in Plant Science

A reciprocal relationship between reactive oxygen species and mitochondrial dynamics in neurodegeneration

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Protein AMPylation by an Evolutionarily Conserved Pseudokinase

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Proteomic Characterization of the Heart and Skeletal Muscle Reveals Widespread Arginine ADP-Ribosylation by the ARTC1 Ectoenzyme

(2018) Mario Leutert et al.   Cell Reports

Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation

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Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance

(2017) Jorge Burns et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase

(2017) Jeannette Abplanalp et al.   Nature Communications

Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism

(2016) Walter W. Chen et al.   CELL

Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice

(2016) Kathryn F. Mills et al.   Cell Metabolism

Mitochondrial poly(ADP-ribose) polymerase: The Wizard of Oz at work

(2016) Attila Brunyanszki et al.   FREE RADICAL BIOLOGY AND MEDICINE

PKCα and HMGB1 antagonistically control hydrogen peroxide-induced poly-ADP-ribose formation

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Overview on poly(ADP-ribose) immuno-biomedicine and future prospects

(2016) Yoshiyuki KANAI   PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES

Biosensor reveals multiple sources for mitochondrial NAD+

(2016) X. A. Cambronne et al.   SCIENCE

Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue

(2016) Rita Martello et al.   Nature Communications

Nuclear ADP-Ribosylation and Its Role in Chromatin Plasticity, Cell Differentiation, and Epigenetics

(2015) Michael O. Hottiger   Annual Review of Biochemistry

PARPs and ADP-Ribosylation: 50 Years … and Counting

(2015) W. Lee Kraus   MOLECULAR CELL

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

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2016 update of the PRIDE database and its related tools

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Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function

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Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging

(2013) Ana P. Gomes et al.   CELL

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

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The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling

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A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins

(2013) Gražvydas Lukinavičius et al.   Nature Chemistry

Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

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ADP-ribosylhydrolase 3 (ARH3), Not Poly(ADP-ribose) Glycohydrolase (PARG) Isoforms, Is Responsible for Degradation of Mitochondrial Matrix-associated Poly(ADP-ribose)

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Physiological Roles of Mitochondrial Reactive Oxygen Species

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Oligomycin frames a common drug-binding site in the ATP synthase

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The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

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ATP Synthesis, Mitochondrial Function, and Steroid Biosynthesis in Rodent Primary and Tumor Leydig Cells1

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Compartmentation of NAD+ -dependent signalling

(2011) Friedrich Koch-Nolte et al.   FEBS LETTERS

Mammalian Sirtuins: Biological Insights and Disease Relevance

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Mitochondrial Localization of PARP-1 Requires Interaction with Mitofilin and Is Involved in the Maintenance of Mitochondrial DNA Integrity

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(2009) Alberto Horenstein et al.   MOLECULAR MEDICINE

Nicotinic Acid, Nicotinamide, and Nicotinamide Riboside: A Molecular Evaluation of NAD+ Precursor Vitamins in Human Nutrition

(2008) Katrina L Bogan et al.   Annual Review of Nutrition

The Role of External and Matrix pH in Mitochondrial Reactive Oxygen Species Generation

(2008) Vitaly A. Selivanov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

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