The adiponectin agonist, AdipoRon, inhibits steroidogenesis and cell proliferation in human luteinized granulosa cells

Mechanisms of Adiponectin Action in Fertility: An Overview from Gametogenesis to Gestation in Humans and Animal Models in Normal and Pathological Conditions

(2019) Alix Barbe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Emerging Role of Adiponectin in Female Malignancies

(2019) Luca Gelsomino et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of adiponectin/peroxisome proliferator-activated receptor alpha signaling in human chorionic gonadotropin-induced estradiol synthesis in human luteinized granulosa cells

(2019) Tao Tao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells

(2019) Amin A. Ramzan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibitor of apoptosis proteins are potential targets for treatment of granulosa cell tumors – implications from studies in KGN

(2019) Konstantin Bagnjuk et al.   Journal of Ovarian Research

Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy

(2018) Sun Ryoung Choi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage

(2018) Anja Baufeld et al.   Reproductive Biology and Endocrinology

The molecular mechanism of ovarian granulosa cell tumors

(2018) Jiaheng Li et al.   Journal of Ovarian Research

Antidiabetic adiponectin receptor agonist AdipoRon suppresses tumour growth of pancreatic cancer by inducing RIPK1/ERK-dependent necroptosis

(2018) Miho Akimoto et al.   Cell Death & Disease

Mitochondrial respiratory chain complex abnormal expressions and fusion disorder are involved in fluoride-induced mitochondrial dysfunction in ovarian granulosa cells

(2018) Wen-peng Zhao et al.   CHEMOSPHERE

Cell Cycle Control by PTEN

(2017) Andrew Brandmaier et al.   JOURNAL OF MOLECULAR BIOLOGY

Adiponectin receptor agonist AdipoRon suppresses adipogenesis in C3H10T1/2 cells through the adenosine monophosphate-activated protein kinase signaling pathway

(2017) Shu-Juan Wang et al.   Molecular Medicine Reports

AdipoRon, an adiponectin receptor agonist, attenuates PDGF-induced VSMC proliferation through inhibition of mTOR signaling independent of AMPK: Implications toward suppression of neointimal hyperplasia

(2017) Arwa Fairaq et al.   PHARMACOLOGICAL RESEARCH

Evaluation of the Cytotoxicity and Genotoxicity of Flavonolignans in Different Cellular Models

(2017) Michal Bijak et al.   Nutrients

Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells

(2016) J. Roche et al.   BIOLOGY OF REPRODUCTION

Adiponectin Deficiency Leads to Female Subfertility and Ovarian Dysfunctions in Mice

(2016) Lixian Cheng et al.   ENDOCRINOLOGY

Prohibitin regulates the FSH signaling pathway in rat granulosa cell differentiation

(2016) Indrajit Chowdhury et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings

(2015) Yanqing Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

17β-estradiol inhibits spreading of metastatic cells from granulosa cell tumors through a non-genomic mechanism involving GPER1

(2015) Charlotte M. François et al.   CARCINOGENESIS

Development and validation of a method using supported liquid extraction for aldosterone determination in human plasma by LC-MS/MS

(2015) Cécile Meunier et al.   CLINICA CHIMICA ACTA

Downregulation of adiponectin system in granulosa cells and low levels of HMW adiponectin in PCOS

(2015) Tayebe Artimani et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Mitochondrial dysfunction and longevity in animals: Untangling the knot

(2015) Y. Wang et al.   SCIENCE

AdipoRon: a possible drug for colorectal cancer prevention?

(2015) Sara Malih et al.   TUMOR BIOLOGY

Effect of adiponectin on cardiac β-catenin signaling pathway under angiotensin II infusion

(2014) Yuya Fujishima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial respiratory chain complexes as sources and targets of thiol-based redox-regulation

(2014) Stefan Dröse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

PI3K/PTEN/Akt and TSC/mTOR signaling pathways, ovarian dysfunction, and infertility: an update

(2014) Annu Makker et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Role of adipokines and cytokines in obesity-associated breast cancer: Therapeutic targets

(2013) Sajid Khan et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

(2013) Miki Okada-Iwabu et al.   NATURE

Developmental Expression of Translocator Protein/Peripheral Benzodiazepine Receptor in Reproductive Tissues

(2013) Kanako Morohaku et al.   PLoS One

Inactivation of AMPKα1 Induces Asthenozoospermia and Alters Spermatozoa Morphology

(2012) Pauline Tartarin et al.   ENDOCRINOLOGY

Women with reduced ovarian reserve or advanced maternal age have an altered follicular environment

(2012) Leanne Pacella et al.   FERTILITY AND STERILITY

Paracrine and Endocrine Effects of Adipose Tissue on Cancer Development and Progression

(2011) Jiyoung Park et al.   ENDOCRINE REVIEWS

A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications

(2011) Céline Raymond et al.   METHODS

Adiponectin Represses Colon Cancer Cell Proliferation via AdipoR1- and -R2-Mediated AMPK Activation

(2010) A Young Kim et al.   MOLECULAR ENDOCRINOLOGY

Aromatase Is a Direct Target of FOXL2: C134W in Granulosa Cell Tumors via a Single Highly Conserved Binding Site in the Ovarian Specific Promoter

(2010) Nicholas I. Fleming et al.   PLoS One

Effect of adiponectin on bovine granulosa cell steroidogenesis, oocyte maturation and embryo development

(2010) Virginie Maillard et al.   Reproductive Biology and Endocrinology

Systemic Fate of the Adipocyte-Derived Factor Adiponectin

(2009) N. Halberg et al.   DIABETES

Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN

(2009) P. Pierre et al.   HUMAN REPRODUCTION

Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases

(2009) T Yamauchi et al.   INTERNATIONAL JOURNAL OF OBESITY

Mouse Oocyte Control of Granulosa Cell Development and Function: Paracrine Regulation of Cumulus Cell Metabolism

(2009) You-Qiang Su et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression

(2008) Marie-Noëlle Laguë et al.   CARCINOGENESIS

Adiponectin increases insulin-like growth factor I-induced progesterone and estradiol secretion in human granulosa cells

(2008) Christine Chabrolle et al.   FERTILITY AND STERILITY

Role of adiponectin in regulating ovarian theca and granulosa cell function

(2008) Dana V. Lagaly et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Adipokines and the Peripheral and Neural Control of Energy Balance

(2008) Rexford S. Ahima et al.   MOLECULAR ENDOCRINOLOGY