Computational study of pomegranate peel extract polyphenols as potential inhibitors of SARS-CoV-2 virus internalization

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

(2020) Daniel Wrapp et al.   SCIENCE

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine

(2020) Wanbo Tai et al.   Cellular & Molecular Immunology

Clinical Features of 69 Cases With Coronavirus Disease 2019 in Wuhan, China

(2020) Zhongliang Wang et al.   CLINICAL INFECTIOUS DISEASES

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

(2020) Xueting Yao et al.   CLINICAL INFECTIOUS DISEASES

SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells

(2020) Soeren Lukassen et al.   EMBO JOURNAL

The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

(2020) Paolo Verdecchia et al.   European Journal of Internal Medicine

A Multibasic Cleavage Site in the Spike Protein of SARS-CoV-2 Is Essential for Infection of Human Lung Cells

(2020) Markus Hoffmann et al.   MOLECULAR CELL

SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes

(2020) Waradon Sungnak et al.   NATURE MEDICINE

Compassionate Use of Remdesivir for Patients with Severe Covid-19

(2020) Jonathan Grein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses

(2020) Shibo Jiang et al.   TRENDS IN IMMUNOLOGY

A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease

(2020) Donald C. Hall et al.   Travel Medicine and Infectious Disease

Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

(2020) Sisi Kang et al.   Acta Pharmaceutica Sinica B

SARS-CoV-2 and Coronavirus Disease 2019: What We Know So Far

(2020) Firas A. Rabi et al.   Pathogens

Blockade of SARS-CoV-2 infection by recombinant soluble ACE2

(2020) Francois Alhenc-Gelas et al.   KIDNEY INTERNATIONAL

Viral dynamics in mild and severe cases of COVID-19

(2020) Yang Liu et al.   LANCET INFECTIOUS DISEASES

Beneficial effects of pomegranate peel extract on plasma lipid profile, fatty acids levels and blood pressure in patients with diabetes mellitus type-2: A randomized, double-blind, placebo-controlled study

(2019) Milkica Grabež et al.   Journal of Functional Foods

Functional analysis of potential cleavage sites in the MERS-coronavirus spike protein

(2018) Hannah Kleine-Weber et al.   Scientific Reports

Could Pomegranate Juice Help in the Control of Inflammatory Diseases?

(2017) Francesca Danesi et al.   Nutrients

The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses

(2016) Eve-Isabelle Pécheur et al.   JOURNAL OF VIROLOGY

SARS and MERS: recent insights into emerging coronaviruses

(2016) Emmie de Wit et al.   NATURE REVIEWS MICROBIOLOGY

Pomegranate peel and peel extracts: Chemistry and food features

(2015) Saeed Akhtar et al.   FOOD CHEMISTRY

Punicalagin Inhibits Inflammation in LPS-Induced RAW264.7 Macrophages via the Suppression of TLR4-Mediated MAPKs and NF-κB Activation

(2014) Xiaolong Xu et al.   INFLAMMATION

The antioxidative and anti-proliferative potential of non-edible organs of the pomegranate fruit and tree

(2014) Ola Orgil et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

A simple method for finding a protein’s ligand-binding pockets

(2014) Seyed Saberi Fathi et al.   BMC STRUCTURAL BIOLOGY

Small molecule inhibitors of HCV replication from Pomegranate

(2014) B. Uma Reddy et al.   Scientific Reports

The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice

(2013) Aishah Al-Jarallah et al.   ATHEROSCLEROSIS

The Pomegranate: Effects on Bacteria and Viruses That Influence Human Health

(2013) Amy B. Howell et al.   Evidence-based Complementary and Alternative Medicine

Pomegranate and type 2 diabetes

(2013) Saleem Banihani et al.   NUTRITION RESEARCH

Combining Global and Local Measures for Structure-Based Druggability Predictions

(2011) Andrea Volkamer et al.   Journal of Chemical Information and Modeling

Analyzing the Topology of Active Sites: On the Prediction of Pockets and Subpockets

(2010) Andrea Volkamer et al.   Journal of Chemical Information and Modeling

Dewetting transitions in protein cavities

(2010) Tom Young et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Pomegranate (Punica granatum) purified polyphenol extract inhibits influenza virus and has a synergistic effect with oseltamivir

(2009) Mehran Haidari et al.   PHYTOMEDICINE

Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration

(2008) Özlem Doğan Ekici et al.   PROTEIN SCIENCE