Orai1, a Direct Target of microRNA-519, Promotes Progression of Colorectal Cancer via Akt/GSK3β Signaling Pathway

Orai1 forms a signal complex with SK3 channel in gallbladder smooth muscle

(2015) Kai Song et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-106b induces cell radioresistance via the PTEN/PI3K/AKT pathways and p21 in colorectal cancer

(2015) Lin Zheng et al.   Journal of Translational Medicine

Elevated Orai1 expression mediates tumor-promoting intracellular Ca2+ oscillations in human esophageal squamous cell carcinoma

(2015) Hua Zhu et al.   Oncotarget

As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway

(2013) L Liu et al.   ONCOGENE

Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent

(2013) F M Davis et al.   ONCOGENE

Lipid rafts couple store-operated Ca 2+ entry to constitutive activation of PKB/Akt in a Ca 2+ /calmodulin-, Src- and PP2A-mediated pathway and promote melanoma tumor growth

(2012) Shlomit Fedida-Metula et al.   CARCINOGENESIS

Growth Inhibition by miR-519 via Multiple p21-Inducing Pathways

(2012) K. Abdelmohsen et al.   MOLECULAR AND CELLULAR BIOLOGY

Calcium store sensor stromal-interaction molecule 1-dependent signaling plays an important role in cervical cancer growth, migration, and angiogenesis

(2011) Y.-F. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic strategy in unresectable metastatic colorectal cancer

(2011) Benoist Chibaudel et al.   Therapeutic Advances in Medical Oncology

NFκB inhibitors induce cell death in glioblastomas

(2010) Alfeu Zanotto-Filho et al.   BIOCHEMICAL PHARMACOLOGY

miR-519 suppresses tumor growth by reducing HuR levels

(2010) Kotb Abdelmohsen et al.   CELL CYCLE

Phase I pharmacokinetic and pharmacodynamic study of triciribine phosphate monohydrate, a small-molecule inhibitor of AKT phosphorylation, in adult subjects with solid tumors containing activated AKT

(2010) Christopher R. Garrett et al.   INVESTIGATIONAL NEW DRUGS

Calcium wave signaling in cancer cells

(2010) Jai Parkash et al.   LIFE SCIENCES

Store-operated CRAC channels: function in health and disease

(2010) Anant B. Parekh   NATURE REVIEWS DRUG DISCOVERY

ORAI-mediated calcium entry: Mechanism and roles, diseases and pharmacology

(2010) Sarah J. Roberts-Thomson et al.   PHARMACOLOGY & THERAPEUTICS

Worldwide Variations in Colorectal Cancer

(2009) M. M. Center et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Orai1 and STIM1 Are Critical for Breast Tumor Cell Migration and Metastasis

(2009) Shengyu Yang et al.   CANCER CELL

The PKB/AKT Pathway in Cancer

(2009) Amancio Carnero   CURRENT PHARMACEUTICAL DESIGN

The microRNA network and tumor metastasis

(2009) H Zhang et al.   ONCOGENE

Soft Substrate Up-regulates the Interaction of STIM1 with Store-operated Ca2+ Channels That Lead to Normal Epithelial Cell Apoptosis

(2008) Wen-Tai Chiu et al.   MOLECULAR BIOLOGY OF THE CELL

miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels

(2008) K. Abdelmohsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multilevel Regulation of Gene Expression by MicroRNAs

(2008) E. V. Makeyev et al.   SCIENCE