E3 Ubiquitin Ligase RNF114 Inhibits Innate Immune Response to Red-Spotted Grouper Nervous Necrosis Virus Infection in Sea Perch by Targeting MAVS and TRAF3 to Mediate Their Degradation

Peste des Petits Ruminants Virus Nucleocapsid Protein Inhibits Beta Interferon Production by Interacting with IRF3 To Block Its Activation

(2019) Zixiang Zhu et al.   JOURNAL OF VIROLOGY

TRAF 3 IP 3 mediates the recruitment of TRAF 3 to MAVS for antiviral innate immunity

(2019) Wenting Zhu et al.   EMBO JOURNAL

Porcine RING finger protein 114 inhibits classical swine fever virus replication via the K27-linked polyubiquitination of viral NS4B

(2019) Yuexiu Zhang et al.   JOURNAL OF VIROLOGY

Zebrafish TRIM25 Promotes Innate Immune Response to RGNNV Infection by Targeting 2CARD and RD Regions of RIG-I for K63-Linked Ubiquitination

(2019) Yilin Jin et al.   Frontiers in Immunology

Regulation of MAVS activation through post-translational modifications

(2018) Bingyu Liu et al.   CURRENT OPINION IN IMMUNOLOGY

Functional characterization of tumor necrosis factor receptor-associated factor 3 of sea perch ( Lateolabrax japonicas) in innate immune

(2018) Wanwan Zhang et al.   FISH & SHELLFISH IMMUNOLOGY

TRIM29 Negatively Regulates the Type I IFN Production in Response to RNA Virus

(2018) Junji Xing et al.   JOURNAL OF IMMUNOLOGY

Mechanism of pattern recognition receptors (PRRs) and host pathogen interplay in bovine mastitis

(2018) Dinesh Bhattarai et al.   MICROBIAL PATHOGENESIS

Zika Virus Non-structural Protein 4A Blocks the RLR-MAVS Signaling

(2018) Jinzhu Ma et al.   Frontiers in Microbiology

Role of Pattern Recognition Receptors in KSHV Infection

(2018) Timsy Uppal et al.   Cancers

Mitochondria in innate immune signaling

(2018) Balaji Banoth et al.   Translational Research

Transcriptional and chromatin regulation in interferon and innate antiviral gene expression

(2018) Nancy Au-Yeung et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Zebrafish NDRG1a Negatively Regulates IFN Induction by Promoting the Degradation of IRF7

(2018) Long-Feng Lu et al.   JOURNAL OF IMMUNOLOGY

Characterization and immunologic functions of the macrophage migration inhibitory factor from Japanese sea bass, Lateolabrax japonicus

(2018) Feng Xu et al.   FISH & SHELLFISH IMMUNOLOGY

Identification of sea perch ( Lateolabrax japonicus ) ribonucleoprotein PTB-Binding 1 involved in antiviral immune response against RGNNV

(2017) Peng Jia et al.   FISH & SHELLFISH IMMUNOLOGY

Inducible MicroRNA-3570 Feedback Inhibits the RIG-I-Dependent Innate Immune Response to Rhabdovirus in Teleost Fish by Targeting MAVS/IPS-1

(2017) Tianjun Xu et al.   JOURNAL OF VIROLOGY

West Nile Virus NS1 Antagonizes Interferon Beta Production by Targeting RIG-I and MDA5

(2017) Hong-Lei Zhang et al.   JOURNAL OF VIROLOGY

The E3 Ubiquitin Ligase TRIM40 Attenuates Antiviral Immune Responses by Targeting MDA5 and RIG-I

(2017) Chunyuan Zhao et al.   Cell Reports

Identification and characterization of the melanoma differentiation – associated gene 5 in sea perch, Lateolabrax japonicus

(2016) Peng Jia et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Molecular characterization and expression analysis of mitochondrial antiviral signaling protein gene in sea perch, Lateolabrax japonicus

(2016) Peng Jia et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Understanding the interaction between Betanodavirus and its host for the development of prophylactic measures for viral encephalopathy and retinopathy

(2016) Janina Z. Costa et al.   FISH & SHELLFISH IMMUNOLOGY

RNA-Seq analysis of immune-relevant genes in Lateolabrax japonicus during Vibrio anguillarum infection

(2016) Chao Zhao et al.   FISH & SHELLFISH IMMUNOLOGY

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

RNF122 suppresses antiviral type I interferon production by targeting RIG-I CARDs to mediate RIG-I degradation

(2016) Wendie Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estrogen receptor alpha inhibits RLR-mediated immune response via ubiquitinating TRAF3

(2015) Changxing Wang et al.   CELLULAR SIGNALLING

RIG-I specifically mediates group II type I IFN activation in nervous necrosis virus infected zebrafish cells

(2015) Hsu-Yu Chen et al.   FISH & SHELLFISH IMMUNOLOGY

Characterization and expression analysis of laboratory of genetics and physiology 2 gene in sea perch, Lateolabrax japonicus

(2015) Peng Jia et al.   FISH & SHELLFISH IMMUNOLOGY

Ring finger protein 166 potentiates RNA virus-induced interferon-β production via enhancing the ubiquitination of TRAF3 and TRAF6

(2015) Hai-Wei Chen et al.   Scientific Reports

RIG-I-like receptor regulation in virus infection and immunity

(2015) Ying Kai Chan et al.   Current Opinion in Virology

A RING finger protein 114 (RNF114) homolog from Chinese sturgeon (Acipenser sinensis) possesses immune-regulation properties via modulating RIG-I signaling pathway-mediated interferon expression

(2014) Zhiyong Liao et al.   FISH & SHELLFISH IMMUNOLOGY

Identification of RNF114 as a novel positive regulatory protein for T cell activation

(2014) Ping Yang et al.   IMMUNOBIOLOGY

Experimental immunology Potential role of RING finger protein 166 (RNF166), a member of an ubiquitin ligase subfamily, involved in regulation of T cell activation

(2013) Ping Yang et al.   Central European Journal of Immunology

Mandarin Fish Caveolin 1 Interaction with Major Capsid Protein of Infectious Spleen and Kidney Necrosis Virus and Its Role in Early Stages of Infection

(2013) K.-T. Jia et al.   JOURNAL OF VIROLOGY

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades

(2013) Siqi Liu et al.   eLife

Regulation of RLR-mediated innate immune signaling – It is all about keeping the balance

(2011) Katharina Eisenächer et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Functional analysis of the RNF114 psoriasis susceptibility gene implicates innate immune responses to double-stranded RNA in disease pathogenesis

(2011) Marie-José Bijlmakers et al.   HUMAN MOLECULAR GENETICS

The E3 Ubiquitin Ligase RNF5 Targets Virus-Induced Signaling Adaptor for Ubiquitination and Degradation

(2010) B. Zhong et al.   JOURNAL OF IMMUNOLOGY

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex

(2009) Kam-Leung Siu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The E3 Ubiquitin Ligase Triad3A Negatively Regulates the RIG-I/MAVS Signaling Pathway by Targeting TRAF3 for Degradation

(2009) Peyman Nakhaei et al.   PLoS Pathogens

T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain

(2008) Ana Lucia Giannini et al.   BIOCHEMICAL JOURNAL

Identification of ZNF313 / RNF114 as a novel psoriasis susceptibility gene

(2008) Francesca Capon et al.   HUMAN MOLECULAR GENETICS

Riplet/RNF135, a RING Finger Protein, Ubiquitinates RIG-I to Promote Interferon-β Induction during the Early Phase of Viral Infection

(2008) Hiroyuki Oshiumi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY