Salmonella Flagellin Activates NAIP/NLRC4 and Canonical NLRP3 Inflammasomes in Human Macrophages

Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction

(2020) Angélique Chevriaux et al.   Frontiers in Cell and Developmental Biology

The Ultimate qPCR Experiment: Producing Publication Quality, Reproducible Data the First Time

(2019) Sean C. Taylor et al.   TRENDS IN BIOTECHNOLOGY

Recent advances in the mechanisms of NLRP3 inflammasome activation and its inhibitors

(2019) Yang Yang et al.   Cell Death & Disease

Sequence determinants of specific pattern-recognition of bacterial ligands by the NAIP–NLRC4 inflammasome

(2018) Jingyi Yang et al.   Cell Discovery

Cytosolic Recognition of Microbes and Pathogens: Inflammasomes in Action

(2018) Jenni A. Hayward et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

The Salmonella pathogenicity island-2 subverts human NLRP3 and NLRC4 inflammasome responses

(2018) Damien Bierschenk et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The NLRC4 Inflammasome

(2017) Joseph A. Duncan et al.   IMMUNOLOGICAL REVIEWS

The human NAIP-NLRC4-inflammasome senses the Pseudomonas aeruginosa T3SS inner-rod protein

(2017) Teddy Grandjean et al.   INTERNATIONAL IMMUNOLOGY

Salmonella- induced inflammasome activation in humans

(2017) Damien Bierschenk et al.   MOLECULAR IMMUNOLOGY

Broad detection of bacterial type III secretion system and flagellin proteins by the human NAIP/NLRC4 inflammasome

(2017) Valeria M. Reyes Ruiz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion

(2017) Jeannette L. Tenthorey et al.   SCIENCE

Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner

(2017) Jungmin Yang et al.   Frontiers in Immunology

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation

(2016) Deepika Sharma et al.   JOURNAL OF CELL BIOLOGY

NAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo

(2016) Isabella Rauch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NLRP3 recruitment by NLRC4 duringSalmonellainfection

(2016) Yan Qu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Novel Roles for Caspase-8 in IL-1β and Inflammasome Regulation

(2015) Prajwal Gurung et al.   AMERICAN JOURNAL OF PATHOLOGY

The NAIP/NLRC4 inflammasomes

(2015) Russell E Vance   CURRENT OPINION IN IMMUNOLOGY

Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin

(2015) Jens Kortmann et al.   JOURNAL OF IMMUNOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes

(2014) Jeannette L. Tenthorey et al.   MOLECULAR CELL

Inefficient star formation in extremely metal poor galaxies

(2014) Yong Shi et al.   NATURE

Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex

(2014) S. M. Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cutting Edge: Mouse NAIP1 Detects the Type III Secretion System Needle Protein

(2013) M. Rayamajhi et al.   JOURNAL OF IMMUNOLOGY

Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responses

(2013) S. L. Lage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

(2013) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential Requirements for NAIP5 in Activation of the NLRC4 Inflammasome

(2011) Karla L. Lightfield et al.   INFECTION AND IMMUNITY

Distinct Roles for Nod2 Protein and Autocrine Interleukin-1β in Muramyl Dipeptide-induced Mitogen-activated Protein Kinase Activation and Cytokine Secretion in Human Macrophages

(2011) Matija Hedl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense againstSalmonella

(2010) Petr Broz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Pseudomonas aeruginosa activates caspase 1 through Ipaf

(2008) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA