Long-term bisphenol A exposure exacerbates diet-induced prediabetes via TLR4-dependent hypothalamic inflammation

Estrogen-dependent hypersensitivity to diabetes-evoked cardiac autonomic dysregulation: Role of hypothalamic neuroinflammation

(2020) Mohamed A. Fouda et al.   LIFE SCIENCES

Molecular Mechanisms Underlying Obesity-Induced Hypothalamic Inflammation and Insulin Resistance: Pivotal Role of Resistin/TLR4 Pathways

(2019) Yacir Benomar et al.   Frontiers in Endocrinology

Oestrogen receptor β mediates the actions of bisphenol-A on ion channel expression in mouse pancreatic beta cells

(2019) Juan Martinez-Pinna et al.   DIABETOLOGIA

Bisphenol a: A narrative review of prenatal exposure effects on adipogenesis and childhood obesity via peroxisome proliferator-activated receptor gamma

(2019) Lori A. Hoepner   ENVIRONMENTAL RESEARCH

Maternal exposure to environmentally relevant doses of bisphenol A causes reproductive dysfunction in F1 adult male rats: protective role of melatonin

(2019) Samuel Gbadebo Olukole et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Non-alcoholic Fatty Liver Disease Induced by Perinatal Exposure to Bisphenol a Is Associated With Activated mTOR and TLR4/NF-κB Signaling Pathways in Offspring Rats

(2019) Ren Lin et al.   Frontiers in Endocrinology

Exposure to Bisphenol A and Bisphenol S and Incident Type 2 Diabetes: A Case–Cohort Study in the French Cohort D.E.S.I.R.

(2019) Fanny Rancière et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Blocking of Estradiol Receptors ERα, ERβ and GPER During Development, Differentially Alters Energy Metabolism in Male and Female Rats

(2019) Beatriz Carrillo et al.   NEUROSCIENCE

Hypothalamic inflammation and malfunctioning glia in the pathophysiology of obesity and diabetes: Translational significance

(2018) Md Habibur Rahman et al.   BIOCHEMICAL PHARMACOLOGY

Epigenetic regulation of astrocyte function in neuroinflammation and neurodegeneration

(2018) Matthew Neal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bisphenol A exposure through receipt handling and its association with insulin resistance among female cashiers

(2018) Inae Lee et al.   ENVIRONMENT INTERNATIONAL

Environmentally relevant levels of bisphenol A affect uterine decidualization and embryo implantation through the estrogen receptor/serum and glucocorticoid-regulated kinase 1/epithelial sodium ion channel α-subunit pathway in a mouse model

(2018) Mu Yuan et al.   FERTILITY AND STERILITY

Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes

(2018) Souvarish Sarkar et al.   NEUROTOXICOLOGY

Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

(2018) Wenlong Sun et al.   PHYTOMEDICINE

Effects of perinatal exposure to BPA and its alternatives (BPS, BPF and BPAF) on hepatic lipid and glucose homeostasis in female mice adolescent offspring

(2018) Zhiyuan Meng et al.   CHEMOSPHERE

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity

(2018) V. Alexandra Moser et al.   Journal of Neuroinflammation

Decreased Capacity for Sperm Production Induced by Perinatal Bisphenol A Exposure Is Associated with an Increased Inflammatory Response in the Offspring of C57BL/6 Male Mice

(2018) Yuan Meng et al.   International Journal of Environmental Research and Public Health

Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice

(2017) Caroline Tao et al.   ENDOCRINOLOGY

Perinatal Exposure to Low-Dose Bisphenol-A Disrupts the Structural and Functional Development of the Hypothalamic Feeding Circuitry

(2017) Harry MacKay et al.   ENDOCRINOLOGY

Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring

(2017) Amita Bansal et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Systematic Review and Meta-Analysis of Early-Life Exposure to Bisphenol A and Obesity-Related Outcomes in Rodents

(2017) Pim Nicolaas Hubertus Wassenaar et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Effects of Low-Dose Developmental Bisphenol A Exposure on Metabolic Parameters and Gene Expression in Male and Female Fischer 344 Rat Offspring

(2017) Margareta H. Lejonklou et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Knockdown of Tlr4 in the Arcuate Nucleus Improves Obesity Related Metabolic Disorders

(2017) Yongli Zhao et al.   Scientific Reports

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Urinary bisphenol A is associated with insulin resistance and obesity in reproductive-aged women

(2016) So-hyeon Hong et al.   CLINICAL ENDOCRINOLOGY

Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation

(2016) Caroline André et al.   DIABETES

Association of early life exposure to bisphenol A with obesity and cardiometabolic traits in childhood

(2016) Marina Vafeiadi et al.   ENVIRONMENTAL RESEARCH

Long-term effects of adolescent exposure to bisphenol A on neuron and glia number in the rat prefrontal cortex: Differences between the sexes and cell type

(2016) Leslie M. Wise et al.   NEUROTOXICOLOGY

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals

(2016) Julie A. Chowen et al.   PROGRESS IN NEUROBIOLOGY

Hypothalamic Inflammation in the Control of Metabolic Function

(2015) Martin Valdearcos et al.   Annual Review of Physiology

Brain Innate Immunity Regulates Hypothalamic Arcuate Neuronal Activity and Feeding Behavior

(2015) Wagner L. Reis et al.   ENDOCRINOLOGY

Bisphenol-A Treatment During Pregnancy in Mice: A New Window of Susceptibility for the Development of Diabetes in Mothers Later in Life

(2015) Paloma Alonso-Magdalena et al.   ENDOCRINOLOGY

A Stereological Analysis of NPY, POMC, Orexin, GFAP Astrocyte, and Iba1 Microglia Cell Number and Volume in Diet-Induced Obese Male Mice

(2015) Moyra B. Lemus et al.   ENDOCRINOLOGY

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation

(2015) Jae-Min Yuk et al.   IMMUNITY

Long-term oral exposure to bisphenol A induces glucose intolerance and insulin resistance

(2015) M. K. Moon et al.   JOURNAL OF ENDOCRINOLOGY

Bisphenol-A Mediated Inhibition of Hippocampal Neurogenesis Attenuated by Curcumin via Canonical Wnt Pathway

(2015) Shashi Kant Tiwari et al.   MOLECULAR NEUROBIOLOGY

Prenatal exposure to bisphenol-A is associated with Toll-like receptor–induced cytokine suppression in neonates

(2015) Sui-Ling Liao et al.   PEDIATRIC RESEARCH

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors

(2015) Liang Yang et al.   Cell Reports

Bisphenol A environmental exposure and the detrimental effects on human metabolic health: is it necessary to revise the risk assessment in vulnerable population?

(2015) R. Valentino et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Reduction of TLR4 mRNA Stability and Protein Expressions through Inhibiting Cytoplasmic Translocation of HuR Transcription Factor by E2 and/or ERα in LPS-Treated H9c2 Cardiomyoblast Cells

(2014) Ming-Jen Fan    CHINESE JOURNAL OF PHYSIOLOGY

Bisphenol a exposure promotes the migration of NCM460 cells via estrogen receptor-mediated integrin β1/MMP-9 pathway

(2014) Tonglin Shi et al.   ENVIRONMENTAL TOXICOLOGY

Bisphenol a regulates the estrogen receptor alpha signaling in developing hippocampus of male rats through estrogen receptor

(2014) Xiao-Bin Xu et al.   HIPPOCAMPUS

Bisphenol A enhances kisspeptin neurons in anteroventral periventricular nucleus of female mice

(2014) Xiaoli Wang et al.   JOURNAL OF ENDOCRINOLOGY

Maternal Bisphenol A Diet Induces Anxiety-Like Behavior in Female Juvenile with Neuroimmune Activation

(2014) Guangying Luo et al.   TOXICOLOGICAL SCIENCES

Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats

(2014) Mona I. Churchwell et al.   TOXICOLOGICAL SCIENCES

Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

(2014) Lin Jia et al.   Nature Communications

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function

(2014) Martin Valdearcos et al.   Cell Reports

Hypothalamic PGC-1α Protects Against High-Fat Diet Exposure by Regulating ERα

(2014) Eugenia Morselli et al.   Cell Reports

Tissue-selective estrogen complexes with bazedoxifene prevent metabolic dysfunction in female mice

(2014) Jun Ho Kim et al.   Molecular Metabolism

Relationship between urinary bisphenol A levels and prediabetes among subjects free of diabetes

(2013) Charumathi Sabanayagam et al.   ACTA DIABETOLOGICA

Sex differences in the association of urinary bisphenol-A concentration with selected indices of glucose homeostasis among U.S. adults

(2013) Hind A. Beydoun et al.   ANNALS OF EPIDEMIOLOGY

Organizational Effects of Perinatal Exposure to Bisphenol-A and Diethylstilbestrol on Arcuate Nucleus Circuitry Controlling Food Intake and Energy Expenditure in Male and Female CD-1 Mice

(2013) Harry MacKay et al.   ENDOCRINOLOGY

Perinatally Administered Bisphenol A as a Potential Mammary Gland Carcinogen in Rats

(2013) Nicole Acevedo et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prenatal Bisphenol A Exposure Alters Sex-Specific Estrogen Receptor Expression in the Neonatal Rat Hypothalamus and Amygdala

(2013) Jinyan Cao et al.   TOXICOLOGICAL SCIENCES

Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity

(2013) C Liu et al.   Cell Death & Disease

Hypothalamic inflammation: a double-edged sword to nutritional diseases

(2012) Dongsheng Cai et al.   Annals of the New York Academy of Sciences

Inhibition of Hypothalamic Inflammation Reverses Diet-Induced Insulin Resistance in the Liver

(2012) M. Milanski et al.   DIABETES

Prediabetic Nephropathy as an Early Consequence of the High-Calorie/High-Fat Diet: Relation to Oxidative Stress

(2012) Hanna Shevalye et al.   ENDOCRINOLOGY

Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone through Estrogen Receptor α and β in Vitro

(2012) Yin Li et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prediabetes: a high-risk state for diabetes development

(2012) Adam G Tabák et al.   LANCET

Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways

(2012) Paloma Alonso-Magdalena et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

(2012) Juxue Li et al.   NATURE CELL BIOLOGY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Distinct Hypothalamic Neurons Mediate Estrogenic Effects on Energy Homeostasis and Reproduction

(2011) Yong Xu et al.   Cell Metabolism

Chronic Oral Exposure to Bisphenol A Results in a Nonmonotonic Dose Response in Mammary Carcinogenesis and Metastasis in MMTV-erbB2 Mice

(2011) Sarah Jenkins et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Urinary Bisphenol A (BPA) Concentration Associates with Obesity and Insulin Resistance

(2011) Tiange Wang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Remodeling of the arcuate nucleus energy-balance circuit is inhibited in obese mice

(2011) David E.G. McNay et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Bisphenol A: An endocrine disruptor with widespread exposure and multiple effects

(2011) Beverly S. Rubin   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Disruption of adult expression of sexually selected traits by developmental exposure to bisphenol A

(2011) E. Jasarevic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Twenty-Four Hour Human Urine and Serum Profiles of Bisphenol A during High-Dietary Exposure

(2011) Justin G. Teeguarden et al.   TOXICOLOGICAL SCIENCES

Bisphenol A Exposure during Pregnancy Disrupts Glucose Homeostasis in Mothers and Adult Male Offspring

(2010) Paloma Alonso-Magdalena et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Urinary, Circulating, and Tissue Biomonitoring Studies Indicate Widespread Exposure to Bisphenol A

(2010) Laura N. Vandenberg et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

High-Fat Diet-Induced Neuropathy of Prediabetes and Obesity: Effect of PMI-5011, an Ethanolic Extract ofArtemisia dracunculusL.

(2010) Pierre Watcho et al.   MEDIATORS OF INFLAMMATION

Serum bisphenol A pharmacokinetics and prostate neoplastic responses following oral and subcutaneous exposures in neonatal Sprague–Dawley rats

(2010) Gail S. Prins et al.   REPRODUCTIVE TOXICOLOGY

MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity

(2009) André Kleinridders et al.   Cell Metabolism

Organochlorine Exposure and Incidence of Diabetes in a Cohort of Great Lakes Sport Fish Consumers

(2009) Mary Turyk et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Perinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat

(2009) Emmanuel Somm et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Hypothalamic IKKβ/NF-κB and ER Stress Link Overnutrition to Energy Imbalance and Obesity

(2008) Xiaoqing Zhang et al.   CELL

Tlr-4 Deficiency Selectively Protects Against Obesity Induced by Diets High in Saturated Fat

(2008) Jeremy E. Davis et al.   Obesity

Metabolic Actions of Estrogen Receptor Beta (ERβ) are Mediated by a Negative Cross-Talk with PPARγ

(2008) Anna Foryst-Ludwig et al.   PLoS Genetics

The Integrative Role of CNS Fuel-Sensing Mechanisms in Energy Balance and Glucose Regulation

(2007) Darleen Sandoval et al.   Annual Review of Physiology