Liposomal doxorubicin targeting mitochondria: A novel formulation to enhance anti-tumor effects of Doxil® in vitro and in vivo

Preparation and characterization of stable nanoliposomal formulations of curcumin with high loading efficacy: In vitro and in vivo anti-tumor study

(2020) Maryam Karimi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Anti-Epcam Aptamer (Syl3c)-Functionalized Liposome for Targeted Delivery Of Doxorubicin: In Vitro And In Vivo Antitumor Studies in Mice Bearing C26 Colon Carcinoma

(2020) Mohammad Mashreghi et al.   Nanoscale Research Letters

Combination therapy with liposomal doxorubicin and liposomal vaccine containing E75, an HER-2/neu-derived peptide, reduces myeloid-derived suppressor cells and improved tumor therapy

(2020) Parvin Zamani et al.   LIFE SCIENCES

Mitochondrial peptides—appropriate options for therapeutic exploitation

(2019) Lucia-Doina Popov   CELL AND TISSUE RESEARCH

Caspases in Cell Death, Inflammation, and Disease

(2019) Nina Van Opdenbosch et al.   IMMUNITY

MPL nano-liposomal vaccine containing P5 HER2/neu-derived peptide pulsed PADRE as an effective vaccine in a mice TUBO model of breast cancer

(2019) Parvin Zamani et al.   JOURNAL OF CONTROLLED RELEASE

Targeting the leptin receptor: To evaluate therapeutic efficacy and anti-tumor effects of Doxil, in vitro and in vivo in mice bearing C26 colon carcinoma tumor

(2018) Shahrzad Amiri Darban et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Synergistic Protective Effects of Mitochondrial Division Inhibitor 1 and Mitochondria-Targeted Small Peptide SS31 in Alzheimer’s Disease

(2018) P. Hemachandra Reddy et al.   JOURNAL OF ALZHEIMERS DISEASE

Cardiolipin-targeted peptides rejuvenate mitochondrial function, remodel mitochondria, and promote tissue regeneration during aging

(2018) Hazel H. Szeto et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mitochondrial targeting nanodrugs self-assembled from 9-O-octadecyl substituted berberine derivative for cancer treatment by inducing mitochondrial apoptosis pathways

(2018) Jia Song et al.   JOURNAL OF CONTROLLED RELEASE

Stealth Peptides Target Cellular Powerhouses to Fight Rare and Common Age-Related Diseases

(2018) Hazel H. Szeto   PROTEIN AND PEPTIDE LETTERS

Nanoparticles and targeted drug delivery in cancer therapy

(2017) Behdokht Bahrami et al.   IMMUNOLOGY LETTERS

PNC27 anticancer peptide as targeting ligand significantly improved antitumor efficacy of Doxil in HDM2-expressing cells

(2017) Shahrzad Amiri Darban et al.   Nanomedicine

Improvement in the drug delivery and anti-tumor efficacy of PEGylated liposomal doxorubicin by targeting RNA aptamers in mice bearing breast tumor model

(2016) Seyedeh Alia Moosavian et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Targeting, bio distributive and tumor growth inhibiting characterization of anti-HER2 affibody coupling to liposomal doxorubicin using BALB/c mice bearing TUBO tumors

(2016) Javad Akhtari et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tat peptide and hexadecylphosphocholine introduction into pegylated liposomal doxorubicin: An in vitro and in vivo study on drug cellular delivery, release, biodistribution and antitumor activity

(2016) Manouchehr Teymouri et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response

(2015) Lei Jiang et al.   BIOMATERIALS

Investigation of Hexadecylphosphocholine (miltefosine) usage in Pegylated liposomal doxorubicin as a synergistic ingredient: In vitro and in vivo evaluation in mice bearing C26 colon carcinoma and B16F0 melanoma

(2015) Manouchehr Teymouri et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Targeting CD44 expressing cancer cells with anti-CD44 monoclonal antibody improves cellular uptake and antitumor efficacy of liposomal doxorubicin

(2015) Leila Arabi et al.   JOURNAL OF CONTROLLED RELEASE

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Nanomedicines Based Drug Delivery Systems for Anti-Cancer Targeting and Treatment

(2015) Vikas Jain et al.   Current Drug Delivery

Serendipity and the Discovery of Novel Compounds That Restore Mitochondrial Plasticity

(2014) H H Szeto et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The anticancer efficacy of paclitaxel liposomes modified with mitochondrial targeting conjugate in resistant lung cancer

(2013) Jia Zhou et al.   BIOMATERIALS

Peptide-Mediated Liposomal Doxorubicin Enhances Drug Delivery Efficiency and Therapeutic Efficacy in Animal Models

(2013) De-Kuan Chang et al.   PLoS One

Liposomal drug delivery systems: From concept to clinical applications

(2012) Theresa M. Allen et al.   ADVANCED DRUG DELIVERY REVIEWS

Polyethylene Glycol Prevents in Vitro Aggregation of Slightly Negatively-Charged Liposomes Induced by Heparin in the Presence of Bivalent Ions

(2012) Hiroko Shibata et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Liposomes loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE conjugate possess low toxicity, target mitochondria and demonstrate enhanced antitumor effects in vitro and in vivo

(2012) Swati Biswas et al.   JOURNAL OF CONTROLLED RELEASE

Doxil® — The first FDA-approved nano-drug: Lessons learned

(2012) Yechezkel (Chezy) Barenholz   JOURNAL OF CONTROLLED RELEASE

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

(2012) Oktay Tacar et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

The use of mitochondrial targeting resveratrol liposomes modified with a dequalinium polyethylene glycol-distearoylphosphatidyl ethanolamine conjugate to induce apoptosis in resistant lung cancer cells

(2011) Xiao-Xing Wang et al.   BIOMATERIALS

Cardiac side-effects of cancer chemotherapy

(2010) Jean-Jacques Monsuez et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Mitochondrial targeting by use of lipid nanocapsules loaded with SV30, an analogue of the small-molecule Bcl-2 inhibitor HA14-1

(2010) M. Weyland et al.   JOURNAL OF CONTROLLED RELEASE

Targeting mitochondria for cancer therapy

(2010) Simone Fulda et al.   NATURE REVIEWS DRUG DISCOVERY

Doxorubicin pathways

(2010) Caroline F. Thorn et al.   Pharmacogenetics and Genomics

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro

(2009) Partha Mukhopadhyay et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The role of topoisomerase IIα and HER-2 in predicting sensitivity to anthracyclines in breast cancer patients

(2009) Catherine Oakman et al.   CANCER TREATMENT REVIEWS

Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol

(2009) Niravkumar R. Patel et al.   JOURNAL OF LIPOSOME RESEARCH

Targeting lipophilic cations to mitochondria

(2008) Michael P. Murphy   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

A History of Cancer Chemotherapy

(2008) Vincent T. DeVita et al.   CANCER RESEARCH