Congenital heart disease risk loci identified by genome-wide association study in European patients

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Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract

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(2019) Yanxiao Zhang et al.   NATURE GENETICS

The Long Noncoding RNA RPS10P2-AS1 Is Implicated in Autism Spectrum Disorder Risk and Modulates Gene Expression in Human Neuronal Progenitor Cells

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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

(2018) James J. Lee et al.   NATURE GENETICS

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MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

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Genome-wide scan for circulating vascular adhesion protein-1 levels: MACROD2 as a potential transcriptional regulator of adipogenesis

(2018) Yi-Cheng Chang et al.   Journal of Diabetes Investigation

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(2017) Sheng Chih Jin et al.   NATURE GENETICS

DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

(2017) Stephan Nothjunge et al.   Nature Communications

G-T haplotype established by rs3785889-rs16941382 in GOSR2 gene is associated with coronary artery disease in Chinese Han population

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Whole exome sequencing in 342 congenital cardiac left sided lesion cases reveals extensive genetic heterogeneity and complex inheritance patterns

(2017) Alexander H. Li et al.   Genome Medicine

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Genome-wide rare copy number variations contribute to genetic risk for transposition of the great arteries

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Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

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Association between the European GWAS-Identified Susceptibility Locus at Chromosome 4p16 and the Risk of Atrial Septal Defect: A Case-Control Study in Southwest China and a Meta-Analysis

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Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics

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Joint Analysis of Functional Genomic Data and Genome-wide Association Studies of 18 Human Traits

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Increased Frequency of De Novo Copy Number Variants in Congenital Heart Disease by Integrative Analysis of Single Nucleotide Polymorphism Array and Exome Sequence Data

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ADP-Ribosylation: Activation, Recognition, and Removal

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(2014) Paul W Burridge et al.   NATURE METHODS

A detailed comparison of mouse and human cardiac development

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MACROD2overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers

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High-resolution analysis of copy number variants in adults with simple-to-moderate congenital heart disease

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A Haplotype of the GOSR2 Gene Is Associated with Myocardial Infarction in Japanese Men

(2013) Shuo Pan et al.   Genetic Testing and Molecular Biomarkers

Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot

(2013) H. J. Cordell et al.   HUMAN MOLECULAR GENETICS

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(2013) Samir Zaidi et al.   NATURE

A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations

(2013) Zhibin Hu et al.   NATURE GENETICS

Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16

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Five Years of GWAS Discovery

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Contribution of Global Rare Copy-Number Variants to the Risk of Sporadic Congenital Heart Disease

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Rare Copy Number Variants Contribute to Congenital Left-Sided Heart Disease

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Congenital Heart Defects in Europe

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Two-marker association tests yield new disease associations for coronary artery disease and hypertension

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Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls

(2011) Rachel Soemedi et al.   HUMAN MOLECULAR GENETICS

Using the genomic relationship matrix to predict the accuracy of genomic selection

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Birth Prevalence of Congenital Heart Disease Worldwide

(2011) Denise van der Linde et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Rare copy number variations in congenital heart disease patients identify unique genes in left-right patterning

(2011) K. A. Fakhro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GOSR2 Lys67Arg Is Associated With Hypertension in Whites

(2009) Tamra E. Meyer et al.   AMERICAN JOURNAL OF HYPERTENSION

The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer

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The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

(2009) Yongjun Lu et al.   NEURON