Investigation of alkaline effects on Protein A affinity ligands and resins using high resolution mass spectrometry

Protein A chromatography: Challenges and progress in the purification of monoclonal antibodies

(2019) Ana Mayela Ramos‐de‐la‐Peña et al.   JOURNAL OF SEPARATION SCIENCE

Removal of B. cereus cereulide toxin from monoclonal antibody bioprocess feed via two-step Protein A affinity and multimodal chromatography

(2019) Magnus Wetterhall et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Affinity Chromatography: An Enabling Technology for Large Scale Bioprocessing

(2019) Karol M. Łącki et al.   Biotechnology Journal

Evaluation of recent Protein A stationary phase innovations for capture of biotherapeutics

(2018) Timothy M. Pabst et al.   JOURNAL OF CHROMATOGRAPHY A

The role of more than 40 years of improvement in protein A chromatography in the growth of the therapeutic antibody industry

(2016) Glen R. Bolton et al.   BIOTECHNOLOGY PROGRESS

Routes to improve binding capacities of affinity resins demonstrated for Protein A chromatography

(2016) Egbert Müller et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Recent advances in mass spectrometric analysis of protein deamidation

(2016) Piliang Hao et al.   MASS SPECTROMETRY REVIEWS

Nature of foulants and fouling mechanism in the Protein A MabSelect resin cycled in a monoclonal antibody purification process

(2015) Shaojie Zhang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Protein deamidation in biopharmaceutical manufacture: understanding, control and impact

(2015) David Gervais   JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

Effect of cleaning agents and additives on Protein A ligand degradation and chromatography performance

(2015) Lihua Yang et al.   JOURNAL OF CHROMATOGRAPHY A

Improving impurities clearance by amino acids addition to buffer solutions for chromatographic purifications of monoclonal antibodies

(2015) Takashi Ishihara et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A comparison of Protein A chromatographic stationary phases: Performance characteristics for monoclonal antibody purification

(2014) Zhuo Liu et al.   BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY

Maximizing binding capacity for protein A chromatography

(2014) Sanchayita Ghose et al.   BIOTECHNOLOGY PROGRESS

Engineering of novel Staphylococcal Protein A ligands to enable milder elution pH and high dynamic binding capacity

(2014) Timothy M. Pabst et al.   JOURNAL OF CHROMATOGRAPHY A

Remarkable alkaline stability of an engineered protein A as immunoglobulin affinity ligand: C domain having only one amino acid substitution

(2013) Kazunobu Minakuchi et al.   PROTEIN SCIENCE

Local Flexibility Facilitates Oxidization of Buried Methionine Residues

(2012) Kuiran Xu et al.   PROTEIN AND PEPTIDE LETTERS

A tool for increasing the lifetime of chromatography resins

(2011) Anna Grönberg et al.   mAbs

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

(2010) Brian Kelley   mAbs

Development of a rapid sanitization solution for silica-based protein A affinity adsorbents

(2009) Marc Rogers et al.   JOURNAL OF CHROMATOGRAPHY A

A mechanistic study of Protein A chromatography resin lifetime

(2009) Canping Jiang et al.   JOURNAL OF CHROMATOGRAPHY A