Osteoblast‐specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase‐1 engenders insulin resistance in high‐fat diet fed mice

ENPP1 in the Regulation of Mineralization and Beyond

(2019) Fiona Roberts et al.   TRENDS IN BIOCHEMICAL SCIENCES

Protective role of skeletal muscle mass against progression from metabolically healthy to unhealthy phenotype

(2018) Min Jung Lee et al.   CLINICAL ENDOCRINOLOGY

Hypomorphic conditional deletion of E11/Podoplanin reveals a role in osteocyte dendrite elongation

(2017) Katherine A. Staines et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Plasma PPi Deficiency Is the Major, but Not the Exclusive, Cause of Ectopic Mineralization in an Abcc6 –/– Mouse Model of PXE

(2017) Jingyi Zhao et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase

(2017) Shira G. Ziegler et al.   Science Translational Medicine

Bone and Muscle Endocrine Functions: Unexpected Paradigms of Inter-organ Communication

(2016) Gerard Karsenty et al.   CELL

ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

(2014) Robert S. Jansen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mineralisation of collagen rich soft tissues and osteocyte lacunae in Enpp1−/− mice

(2014) Mark O.R. Hajjawi et al.   BONE

Loss of White Adipose Hyperplastic Potential Is Associated with Enhanced Susceptibility to Insulin Resistance

(2014) Soo M. Kim et al.   Cell Metabolism

Deficiency of the bone mineralization inhibitor NPP1 protects mice against obesity and diabetes

(2014) C. Huesa et al.   Disease Models & Mechanisms

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

(2014) Dongxing Zhu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Positive effects of brown adipose tissue on femoral bone structure

(2013) Miriam A. Bredella et al.   BONE

Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy

(2013) Q. Li et al.   Disease Models & Mechanisms

A protective role for FGF-23 in local defence against disrupted arterial wall integrity?

(2013) Dongxing Zhu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

(2013) R. S. Jansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Phosphatases in the Initiation of Skeletal Mineralization

(2012) José Luis Millán   CALCIFIED TISSUE INTERNATIONAL

Young Women with Cold-Activated Brown Adipose Tissue Have Higher Bone Mineral Density and Lower Pref-1 than Women without Brown Adipose Tissue: A Study in Women with Anorexia Nervosa, Women Recovered from Anorexia Nervosa, and Normal-Weight Women

(2012) Miriam A. Bredella et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The contribution of bone to whole-organism physiology

(2012) Gérard Karsenty et al.   NATURE

Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice

(2012) Sharon Lim et al.   Nature Protocols

Cold-activated brown adipose tissue is an independent predictor of higher bone mineral density in women

(2012) P. Lee et al.   OSTEOPOROSIS INTERNATIONAL

Altered Bone Development and an Increase in FGF-23 Expression in Enpp1−/− Mice

(2012) Neil Charles Wallace Mackenzie et al.   PLoS One

Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism

(2011) Yoshihiro Yoshikawa et al.   JOURNAL OF BONE AND MINERAL RESEARCH

NT5EMutations and Arterial Calcifications

(2011) Cynthia St. Hilaire et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Appearance and Modulation of Osteocyte Marker Expression during Calcification of Vascular Smooth Muscle Cells

(2011) Dongxing Zhu et al.   PLoS One

An ELISA-based method to quantify osteocalcin carboxylation in mice

(2010) Mathieu Ferron et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition

(2010) Keertik Fulzele et al.   CELL

The Changed Metabolic World with Human Brown Adipose Tissue: Therapeutic Visions

(2010) Jan Nedergaard et al.   Cell Metabolism

Hypoxia-Independent Angiogenesis in Adipose Tissues during Cold Acclimation

(2009) Yuan Xue et al.   Cell Metabolism

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

New Variants in theEnpp1andPtpn6Genes Cause Low BMD, Crystal-Related Arthropathy, and Vascular Calcification

(2009) Philip Babij et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Insulin signaling regulating genes: effect on T2DM and cardiovascular risk

(2009) Sabrina Prudente et al.   Nature Reviews Endocrinology

The Role of Membrane Glycoprotein Plasma Cell Antigen 1/Ectonucleotide Pyrophosphatase Phosphodiesterase 1 in the Pathogenesis of Insulin Resistance and Related Abnormalities

(2008) Ira D. Goldfine et al.   ENDOCRINE REVIEWS