Extracellular vesicles‐encapsulated let‐7i shed from bone mesenchymal stem cells suppress lung cancer via KDM3A/DCLK1/FXYD3 axis

Extracellular vesicles derived from human adipose-derived stem cells promote the exogenous angiogenesis of fat grafts via the let-7/AGO1/VEGF signalling pathway

(2020) Yuanzheng Zhu et al.   Scientific Reports

Identification of extracellular vesicles-transported miRNAs in Erlotinib-resistant head and neck squamous cell carcinoma

(2020) Yang Zheng et al.   Journal of Cell Communication and Signaling

Hypoxic BMSC-derived exosomal miRNAs promote metastasis of lung cancer cells via STAT3-induced EMT

(2019) Xina Zhang et al.   Molecular Cancer

Comparative expression analysis of let-7 microRNAs during ovary development in Megalobrama amblycephala

(2019) Tian Lan et al.   FISH PHYSIOLOGY AND BIOCHEMISTRY

Extracellular Vesicles in Lung Health, Disease, and Therapy: Mini-Review and Special Call for papers

(2019) Mark John McVey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Increased expression of DCLK1, a novel putative CSC maker, is associated with tumor aggressiveness and worse disease-specific survival in patients with bladder carcinomas

(2019) Somayeh Shafiei et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Let-7 inhibits the migration and invasion of extravillous trophoblast cell via targeting MDM4

(2019) Lili Zhang et al.   MOLECULAR AND CELLULAR PROBES

let-7i inhibits proliferation and migration of bladder cancer cells by targeting HMGA1

(2019) M-M Qin et al.   BMC Urology

The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice

(2019) Prasad Dandawate et al.   GASTROENTEROLOGY

Application of RNA-sequencing to identify transcriptome modification by DCLK1 in colorectal cancer cells

(2019) Lianna Li et al.   CANCER GENE THERAPY

Epigenetic regulation of lung cancer cell proliferation and migration by the chromatin remodeling protein BRG1

(2019) Zilong Li et al.   Oncogenesis

Secretome within the bone marrow microenvironment: A basis for mesenchymal stem cell treatment and role in cancer dormancy

(2018) Hussam S. Eltoukhy et al.   BIOCHIMIE

miR-539 enhances chemosensitivity to cisplatin in non-small cell lung cancer by targeting DCLK1

(2018) Huixing Deng et al.   BIOMEDICINE & PHARMACOTHERAPY

Extracellular Vesicles in Oncology: Progress and Pitfalls in the Methods of Isolation and Analysis

(2018) Donatella Lucchetti et al.   Biotechnology Journal

Knockdown of TGF-β1 expression in human umbilical cord mesenchymal stem cells reverts their exosome-mediated EMT promoting effect on lung cancer cells

(2018) Xiaoyin Zhao et al.   CANCER LETTERS

Extracellular Vesicles in Oncology: Progress and Pitfalls in the Methods of Isolation and Analysis

(2018) Donatella Lucchetti et al.   Biotechnology Journal

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

MicroRNAs from urinary extracellular vesicles are non-invasive early biomarkers of diabetic nephropathy in type 2 diabetes patients with the ‘Asian Indian phenotype’

(2018) P. Prabu et al.   DIABETES & METABOLISM

Analysis of the clinical significance of DCLK1+ colorectal cancer using novel monoclonal antibodies against DCLK1

(2018) Tianqi Dai et al.   OncoTargets and Therapy

Small non-coding RNA landscape of extracellular vesicles from human stem cells

(2018) Sippy Kaur et al.   Scientific Reports

Let-7 microRNA as a potential therapeutic target with implications for immunotherapy

(2018) Maud-Emmanuelle Gilles et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Therapeutic use of mesenchymal stem cell-derived extracellular vesicles in acute lung injury

(2018) Jae Hoon Lee et al.   TRANSFUSION

Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases

(2018) Yu Fujita et al.   Journal of Clinical Medicine

Early detection of lung cancer biomarkers through biosensor technology: A review

(2018) Amir Roointan et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

KDM3A is associated with tumor metastasis and modulates colorectal cancer cell migration and invasion

(2018) Jiaming Liu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

Impact of histone demethylase KDM3A-dependent AP-1 transactivity on hepatotumorigenesis induced by PI3K activation

(2017) T Nakatsuka et al.   ONCOGENE

Extracellular vesicles in lung cancer—From bench to bedside

(2017) Tsukasa Kadota et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

KDM3A promotes inhibitory cytokines secretion by participating in TLR4 regulation of Foxp3 transcription in lung adenocarcinoma cells

(2017) Yinan Li et al.   Oncology Letters

The histone demethylase Kdm3a is required for normal epithelial proliferation, ductal elongation and tumor growth in the mouse mammary gland

(2017) Li Qin et al.   Oncotarget

Nucleolin-targeted Extracellular Vesicles as a Versatile Platform for Biologics Delivery to Breast Cancer

(2017) Yayu Wang et al.   Theranostics

Melanoma cell–derived exosomes promote epithelial–mesenchymal transition in primary melanocytes through paracrine/autocrine signaling in the tumor microenvironment

(2016) Deyi Xiao et al.   CANCER LETTERS

Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases

(2016) Antoine Monsel et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Methylation of the DCLK1 promoter region in circulating free DNA and its prognostic value in lung cancer patients

(2015) T. Powrózek et al.   Clinical & Translational Oncology

Secretome of human bone marrow mesenchymal stem cells: an emerging player in lung cancer progression and mechanisms of translation initiation

(2015) Oshrat Attar-Schneider et al.   TUMOR BIOLOGY

Systemic Administration of Human Bone Marrow-Derived Mesenchymal Stromal Cell Extracellular Vesicles AmelioratesAspergillusHyphal Extract-Induced Allergic Airway Inflammation in Immunocompetent Mice

(2015) Fernanda F. Cruz et al.   Stem Cells Translational Medicine

Deregulation of Serum MicroRNA Expression Is Associated with Cigarette Smoking and Lung Cancer

(2014) Jinkun Huang et al.   Biomed Research International

Polyamines are oncometabolites that regulate the LIN28/let-7 pathway in colorectal cancer cells

(2013) Edwin A. Paz et al.   MOLECULAR CARCINOGENESIS

A Mathematical Model for MicroRNA in Lung Cancer

(2013) Hye-Won Kang et al.   PLoS One

Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells

(2012) Shen Hua et al.   BIOMEDICINE & PHARMACOTHERAPY

Down-Regulation of FXYD3 Expression in Human Lung Cancers

(2009) Koji Okudela et al.   AMERICAN JOURNAL OF PATHOLOGY