Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner

Lipid droplet biogenesis: A mystery “unmixing”?

(2020) Mike F. Renne et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1

(2020) Jonghwa Lee et al.   Life Science Alliance

Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis

(2019) Kamil Sołtysik et al.   Nature Communications

The assembly of lipid droplets and their roles in challenged cells

(2019) W Mike Henne et al.   EMBO JOURNAL

The biogenesis of lipid droplets: Lipids take center stage

(2019) Mingming Gao et al.   PROGRESS IN LIPID RESEARCH

Compartmentalized Synthesis of Triacylglycerol at the Inner Nuclear Membrane Regulates Nuclear Organization

(2019) Antonio D. Barbosa et al.   DEVELOPMENTAL CELL

The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets

(2018) Anete Romanauska et al.   CELL

Architecture of Lipid Droplets in Endoplasmic Reticulum Is Determined by Phospholipid Intrinsic Curvature

(2018) Vineet Choudhary et al.   CURRENT BIOLOGY

Human SEIPIN Binds Anionic Phospholipids

(2018) Renhong Yan et al.   DEVELOPMENTAL CELL

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipid sensing by mTOR complexes viade novosynthesis of phosphatidic acid

(2017) Deepak Menon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Characterization of Phosphatidic Acid Sensors and Their Localization during Frustrated Phagocytosis

(2017) Nawal Kassas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Seipin regulates ER–lipid droplet contacts and cargo delivery

(2016) Veijo T Salo et al.   EMBO JOURNAL

PML isoform II plays a critical role in nuclear lipid droplet formation

(2016) Yuki Ohsaki et al.   JOURNAL OF CELL BIOLOGY

Versatile protein tagging in cells with split fluorescent protein

(2016) Daichi Kamiyama et al.   Nature Communications

SEIPIN Regulates Lipid Droplet Expansion and Adipocyte Development by Modulating the Activity of Glycerol-3-phosphate Acyltransferase

(2016) Martin Pagac et al.   Cell Reports

Seipin is required for converting nascent to mature lipid droplets

(2016) Huajin Wang et al.   eLife

Seipin is involved in the regulation of phosphatidic acid metabolism at a subdomain of the nuclear envelope in yeast

(2015) Heimo Wolinski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Dissecting seipin function: the localized accumulation of phosphatidic acid at ER/LD junctions in the absence of seipin is suppressed by Sei1pΔNterm only in combination with Ldb16p

(2015) Sungwon Han et al.   BMC CELL BIOLOGY

The seipin complex Fld1/Ldb16 stabilizes ER–lipid droplet contact sites

(2015) Alexandra Grippa et al.   JOURNAL OF CELL BIOLOGY

Seipin performs dissectible functions in promoting lipid droplet biogenesis and regulating droplet morphology

(2015) Bethany R. Cartwright et al.   MOLECULAR BIOLOGY OF THE CELL

Acyl-CoA Metabolism and Partitioning

(2014) Trisha J. Grevengoed et al.   Annual Review of Nutrition

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Phosphorylation of Lipin 1 and Charge on the Phosphatidic Acid Head Group Control Its Phosphatidic Acid Phosphatase Activity and Membrane Association

(2013) James M. Eaton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains

(2013) Adam Kassan et al.   JOURNAL OF CELL BIOLOGY

SFRS10—A Splicing Factor Gene Reduced in Human Obesity?

(2012) Mario Brosch et al.   Cell Metabolism

The FATP1–DGAT2 complex facilitates lipid droplet expansion at the ER–lipid droplet interface

(2012) Ningyi Xu et al.   JOURNAL OF CELL BIOLOGY

mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway

(2011) Timothy R. Peterson et al.   CELL

Expression of the Splicing Factor Gene SFRS10 Is Reduced in Human Obesity and Contributes to Enhanced Lipogenesis

(2011) Jussi Pihlajamäki et al.   Cell Metabolism

The nucleoplasmic reticulum: form and function

(2011) Ashraf Malhas et al.   TRENDS IN CELL BIOLOGY

A Role for Phosphatidic Acid in the Formation of “Supersized” Lipid Droplets

(2011) Weihua Fei et al.   PLoS Genetics

Lipin proteins form homo- and hetero-oligomers

(2010) Guang-Hui Liu et al.   BIOCHEMICAL JOURNAL

Functional analysis of two isoforms of phosphatidylethanolamine N-methyltransferase

(2010) Shin-ya Morita et al.   BIOCHEMICAL JOURNAL

Characterization of the HumanLPIN1-encoded Phosphatidate Phosphatase Isoforms

(2010) Gil-Soo Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Phosphatidic Acid Binding/Nuclear Localization Motif Determines Lipin1 Function in Lipid Metabolism and Adipogenesis

(2010) Hongmei Ren et al.   MOLECULAR BIOLOGY OF THE CELL

Enzymatic measurement of phosphatidic acid in cultured cells

(2009) Shin-ya Morita et al.   JOURNAL OF LIPID RESEARCH

Fld1p, a functional homologue of human seipin, regulates the size of lipid droplets in yeast

(2008) Weihua Fei et al.   JOURNAL OF CELL BIOLOGY

Dynamics of component exchange at PML nuclear bodies

(2008) S. Weidtkamp-Peters et al.   JOURNAL OF CELL SCIENCE

Recent progress on acyl CoA: lysophospholipid acyltransferase research

(2008) Hideo Shindou et al.   JOURNAL OF LIPID RESEARCH

The level and compartmentalization of phosphatidate phosphatase-1 (lipin-1) control the assembly and secretion of hepatic VLDL

(2008) Maroun Bou Khalil et al.   JOURNAL OF LIPID RESEARCH