CILAIR-Based Secretome Analysis of Obese Visceral and Subcutaneous Adipose Tissues Reveals Distinctive ECM Remodeling and Inflammation Mediators

Inflammation and the depot-specific secretome of human preadipocytes

(2015) Yi Zhu et al.   Obesity

SILAC for biomarker discovery

(2015) Gunnar Dittmar  et al.   Proteomics Clinical Applications

MECHANISMS IN ENDOCRINOLOGY: White, brown and pink adipocytes: the extraordinary plasticity of the adipose organ

(2014) Antonio Giordano et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Characteristic Expression of Extracellular Matrix in Subcutaneous Adipose Tissue Development and Adipogenesis; Comparison with Visceral Adipose Tissue

(2014) Shinobu Mori et al.   International Journal of Biological Sciences

Crosstalk between Adipocytes and Immune Cells in Adipose Tissue Inflammation and Metabolic Dysregulation in Obesity

(2014) Jin Young Huh et al.   MOLECULES AND CELLS

Obesity: A Gateway Disease with a Rising Prevalence

(2014) Gema Frühbeck et al.   Obesity Facts

The mechanical properties of human adipose tissues and their relationships to the structure and composition of the extracellular matrix

(2013) Nadia Alkhouli et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of periostin in tissue remodeling across health and disease

(2013) Simon J. Conway et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Galectin-3 Deficiency Accelerates High-Fat Diet-Induced Obesity and Amplifies Inflammation in Adipose Tissue and Pancreatic Islets

(2013) N. N. Pejnovic et al.   DIABETES

Adipocyte Fetuin-A Contributes to Macrophage Migration into Adipose Tissue and Polarization of Macrophages

(2013) Priyajit Chatterjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Multiple Challenges of Obesity

(2013) Anthony N. DeMaria   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Adipose tissue-specific modulation of galectin expression in lean and obese mice: Evidence for regulatory function

(2013) Davina H. Rhodes et al.   Obesity

FNDC5/Irisin Is Not Only a Myokine but Also an Adipokine

(2013) Arturo Roca-Rivada et al.   PLoS One

The role of thrombospondin (TSP)-1 in obesity and diabetes

(2013) Ping Kong et al.   Adipocyte

Loss of Coiled-Coil Domain Containing 80 Negatively Modulates Glucose Homeostasis in Diet-Induced Obese Mice

(2012) Frédéric Tremblay et al.   ENDOCRINOLOGY

Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications

(2012) Mi-Jeong Lee et al.   MOLECULAR ASPECTS OF MEDICINE

Global obesity: trends, risk factors and policy implications

(2012) Vasanti S. Malik et al.   Nature Reviews Endocrinology

Functional annotation of the human fat cell secretome

(2012) Ingrid Dahlman et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Clinical Relevance of Adipokines

(2012) Matthias Blüher   Diabetes & Metabolism Journal

Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) controls adipogenesis in obesity in mice and in humans

(2011) B. Meissburger et al.   DIABETOLOGIA

Effect of weight loss on serum pigment epithelium-derived factor levels

(2011) Alexander Tschoner et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Macrophage-induced expression and release of matrix metalloproteinase 1 and 3 by human preadipocytes is mediated by IL-1β via activation of MAPK signaling

(2011) Dan Gao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Secretome analysis of rat adipose tissues shows location-specific roles for each depot type

(2011) Arturo Roca-Rivada et al.   Journal of Proteomics

Elevated circulating levels of the serum acute-phase protein YKL-40 (chitinase 3-like protein 1) are a marker of obesity and insulin resistance in prepubertal children

(2011) Ioannis Kyrgios et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Role of Thrombospondin-2 in Murine Adipose Tissue Angiogenesis and Development

(2011) Matthias Van Hul et al.   Obesity

ITIH-5 Expression in Human Adipose Tissue Is Increased in Obesity

(2011) Åsa Anveden et al.   Obesity

Novel Pathway of Adipogenesis through Cross-Talk between Adipose Tissue Macrophages, Adipose Stem Cells and Adipocytes: Evidence of Cell Plasticity

(2011) Gregorio Chazenbalk et al.   PLoS One

Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation

(2010) Michael Spencer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Intrinsic Depot-Specific Differences in the Secretome of Adipose Tissue, Preadipocytes, and Adipose Tissue-Derived Microvascular Endothelial Cells

(2010) S. L. Hocking et al.   DIABETES

Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases

(2010) Tsuyoshi Kadomatsu et al.   FEBS Journal

Pigment epithelium-derived factor (PEDF) is one of the most abundant proteins secreted by human adipocytes and induces insulin resistance and inflammatory signaling in muscle and fat cells

(2010) S Famulla et al.   INTERNATIONAL JOURNAL OF OBESITY

Increased Circulating and Visceral Adipose Tissue Expression Levels of YKL-40 in Obesity-Associated Type 2 Diabetes Are Related to Inflammation: Impact of Conventional Weight Loss and Gastric Bypass

(2010) Victoria Catalán et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A Robust Method for Quantitative High-throughput Analysis of Proteomes by18O Labeling

(2010) Elena Bonzon-Kulichenko et al.   MOLECULAR & CELLULAR PROTEOMICS

Secreted proteins from adipose tissue and skeletal muscle – adipokines, myokines and adipose/muscle cross-talk

(2010) Paul Trayhurn et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Characterization and comparison of adipose tissue-derived cells from human subcutaneous and omental adipose tissues

(2009) Mito Toyoda et al.   CELL BIOCHEMISTRY AND FUNCTION

Adipose Tissue Collagen VI in Obesity

(2009) Magdalena Pasarica et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

YKL-40 is Elevated in Morbidly Obese Patients and Declines After Weight Loss

(2009) Moritz Hempen et al.   OBESITY SURGERY

Plasma YKL-40: A BMI-Independent Marker of Type 2 Diabetes

(2008) A. R. Nielsen et al.   DIABETES

Plasma pigment epithelium-derived factor is positively associated with obesity in Caucasian subjects, in particular with the visceral fat depot

(2008) Ping Wang et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Comparison of Isotope-labeled Amino Acid Incorporation Rates (CILAIR) Provides a Quantitative Method to Study Tissue Secretomes

(2008) Han Roelofsen et al.   MOLECULAR & CELLULAR PROTEOMICS

Different Transcriptional Control of Metabolism and Extracellular Matrix in Visceral and Subcutaneous Fat of Obese and Rimonabant Treated Mice

(2008) Carine Poussin et al.   PLoS One

Transcriptome-based systematic identification of extracellular matrix proteins

(2008) R.-i. Manabe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA