Alzheimer’s Disease, Neural Plasticity, and Functional Recovery

Evidence of Synaptic and Neurochemical Remodeling in the Retina of Aging Degus

(2020) Lily Y.-L. Chang et al.   Frontiers in Neuroscience

Amygdala stimulation ameliorates memory impairments and promotes c‐Fos activity in fimbria‐fornix‐lesioned rats

(2020) Daymara Mercerón‐Martínez et al.   SYNAPSE

Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degus

(2020) Nibaldo C. Inestrosa et al.   Frontiers in Cell and Developmental Biology

Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration

(2020) B. Mahalakshmi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases

(2019) Yan Liu et al.   LABORATORY INVESTIGATION

After-effects of repetitive anodal transcranial direct current stimulation on learning and memory in a rat model of Alzheimer’s disease

(2019) Wen-Juan Yang et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Transcranial Magnetic and Electrical Stimulation in Alzheimer's disease a Mild Cognitive Impairment: A Review of Randomized Controlled Trials

(2019) Tarek K. Rajji   CLINICAL PHARMACOLOGY & THERAPEUTICS

High-frequency repetitive transcranial magnetic stimulation combined with cognitive training improves cognitive function and cortical metabolic ratios in Alzheimer’s disease

(2019) Fengxia Zhang et al.   JOURNAL OF NEURAL TRANSMISSION

Transcranial direct current stimulation does not improve memory deficits or alter pathological hallmarks in a rodent model of Alzheimer's disease

(2019) Elise Gondard et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Targeting the Synapse in Alzheimer’s Disease

(2019) Johanna Jackson et al.   Frontiers in Neuroscience

Repetitive transcranial magnetic stimulation for cognitive impairment in Alzheimer's disease: a meta-analysis of randomized controlled trials

(2019) Xin Wang et al.   JOURNAL OF NEUROLOGY

Effect of BDNF Val66Met on disease markers in dominantly inherited AD

(2018) Yen Ying Lim et al.   ANNALS OF NEUROLOGY

Amygdala stimulation promotes recovery of behavioral performance in a spatial memory task and increases GAP-43 and MAP-2 in the hippocampus and prefrontal cortex of male rats

(2018) D. Mercerón-Martínez et al.   BRAIN RESEARCH BULLETIN

β-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals

(2018) Hsin-Yi Wu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanisms of neurotrophin trafficking via Trk receptors

(2018) Emily Scott-Solomon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Functional organization of postsynaptic glutamate receptors

(2018) Nicky Scheefhals et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Environmental enrichment and exercise are better than social enrichment to reduce memory deficits in amyloid beta neurotoxicity

(2018) Mariza G. Prado Lima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Plasticity in the Brain of Insects and Rodents

(2018) Wojciech Krzeptowski et al.   Frontiers in Neural Circuits

Exercise Intervention Associated with Cognitive Improvement in Alzheimer’s Disease

(2018) Meng Ying Cui et al.   NEURAL PLASTICITY

Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease

(2018) Eleanor K. Pickett et al.   ACTA NEUROPATHOLOGICA

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

(2018) Se Hoon Choi et al.   SCIENCE

Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer's disease mice

(2017) Jennifer N. Perusini et al.   HIPPOCAMPUS

Effects of Physical Exercise on Alzheimer’s Disease Biomarkers: A Systematic Review of Intervention Studies

(2017) Kristian Steen Frederiksen et al.   JOURNAL OF ALZHEIMERS DISEASE

Effects of aging on functional and structural brain connectivity

(2017) Jessica S. Damoiseaux   NEUROIMAGE

Emotional Modulation of Learning and Memory: Pharmacological Implications

(2017) Ryan T. LaLumiere et al.   PHARMACOLOGICAL REVIEWS

Direct electrical stimulation of the amygdala enhances declarative memory in humans

(2017) Cory S. Inman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CSF tau is associated with impaired cortical plasticity, cognitive decline and astrocyte survival only in APOE4-positive Alzheimer’s disease

(2017) Giacomo Koch et al.   Scientific Reports

AGE-DEPENDENT HIPPOCAMPAL CHANGES IN OCTODON DEGUS

(2016) Peter A. Angeli et al.   Alzheimers & Dementia

BDNFVal66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer’s disease

(2016) Yen Ying Lim et al.   BRAIN

Amygdala electrical stimulation inducing spatial memory recovery produces an increase of hippocampal bdnf and arc gene expression

(2016) D. Mercerón-Martínez et al.   BRAIN RESEARCH BULLETIN

Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor

(2016) Andres Gonzalez et al.   Cytoskeleton

Treatment of Alzheimer's Disease with Repetitive Transcranial Magnetic Stimulation Combined with Cognitive Training: A Prospective, Randomized, Double-Blind, Placebo-Controlled Study

(2016) Juyoun Lee et al.   Journal of Clinical Neurology

Repetitive transcranial magnetic stimulation (rTMS) combined with cognitive training is a safe and effective modality for the treatment of Alzheimer’s disease: clinical experience

(2016) Jose Martin Rabey et al.   JOURNAL OF NEURAL TRANSMISSION

Neural plasticity and behavior - sixty years of conceptual advances

(2016) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY

Altered Proteins in the Aging Brain

(2016) Adila Elobeid et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

(2016) Dheeraj S. Roy et al.   NATURE

Ageing, neurodegeneration and brain rejuvenation

(2016) Tony Wyss-Coray   NATURE

Fear Memory

(2016) Ivan Izquierdo et al.   PHYSIOLOGICAL REVIEWS

Repetitive transcranial magnetic stimulation improves cognitive function of Alzheimer’s disease patients

(2016) Junwu Zhao et al.   Oncotarget

Transcranial direct current stimulation as a memory enhancer in patients with Alzheimer’s disease: a randomized, placebo-controlled trial

(2016) Martin Bystad et al.   Alzheimers Research & Therapy

Changes in cerebral glucose metabolism after 3 weeks of noninvasive electrical stimulation of mild cognitive impairment patients

(2016) Kyongsik Yun et al.   Alzheimers Research & Therapy

Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer’s disease

(2016) S-S Jiao et al.   Translational Psychiatry

The importance of burrowing, climbing and standing upright for laboratory rats

(2016) I. Joanna Makowska et al.   Royal Society Open Science

Age Progression of Neuropathological Markers in the Brain of the Chilean RodentOctodon degus, a Natural Model of Alzheimer's Disease

(2015) Nibaldo C. Inestrosa et al.   BRAIN PATHOLOGY

Natural AD-Like Neuropathology in Octodon degus: Impaired Burrowing and Neuroinflammation

(2015) Robert Deacon et al.   Current Alzheimer Research

Protective Effects of Physical Exercise in Alzheimer's Disease and Parkinson's Disease: A Narrative Review

(2015) Thierry Paillard et al.   Journal of Clinical Neurology

Comparison of the Effect of Exercise on Late-Phase LTP of the Dentate Gyrus and CA1 of Alzheimer’s Disease Model

(2015) An T. Dao et al.   MOLECULAR NEUROBIOLOGY

Evidence cerebral blood-flow regulation mediates exercise–cognition links in healthy young adults.

(2015) Hayley Guiney et al.   NEUROPSYCHOLOGY

Treadmill exercise enhances synaptic plasticity, but does not alter β-amyloid deposition in hippocampi of aged APP/PS1 transgenic mice

(2015) G. Zhao et al.   NEUROSCIENCE

Intraperitoneal Administration of a Novel TAT-BDNF Peptide Ameliorates Cognitive Impairments via Modulating Multiple Pathways in Two Alzheimer’s Rodent Models

(2015) Yuanyuan Wu et al.   Scientific Reports

Brain-Derived Neurotrophic Factor Ameliorates Learning Deficits in a Rat Model of Alzheimer's Disease Induced by Aβ1-42

(2015) Lu Zhang et al.   PLoS One

Alzheimer’s Disease-Related Protein Expression in the Retina of Octodon degus

(2015) Lucia Y. Du et al.   PLoS One

Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits

(2014) Eric C. Miller et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The learning of fear extinction

(2014) Cristiane Furini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Treadmill Exercise Prevents Learning and Memory Impairment in Alzheimer’s Disease-Like Pathology

(2013) An T. Dao et al.   Current Alzheimer Research

Early BDNF Treatment Ameliorates Cell Loss in the Entorhinal Cortex of APP Transgenic Mice

(2013) A. H. Nagahara et al.   JOURNAL OF NEUROSCIENCE

BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases

(2013) Bai Lu et al.   NATURE REVIEWS NEUROSCIENCE

Biochemistry and Cell Biology of Tau Protein in Neurofibrillary Degeneration

(2013) E.-M. Mandelkow et al.   Cold Spring Harbor Perspectives in Medicine

Expression of NMDA receptor-dependent LTP in the hippocampus: bridging the divide

(2013) Tim VP Bliss et al.   Molecular Brain

The Secreted Wnt Antagonist Dickkopf-1 Is Required for Amyloid  -Mediated Synaptic Loss

(2012) S. A. Purro et al.   JOURNAL OF NEUROSCIENCE

Neurotrophin regulation of neural circuit development and function

(2012) Hyungju Park et al.   NATURE REVIEWS NEUROSCIENCE

Postsynaptic dysfunction is associated with spatial and object recognition memory loss in a natural model of Alzheimer's disease

(2012) A. O. Ardiles et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Burrow limitations and group living in the communally rearing rodent,Octodon degus

(2011) Luis A. Ebensperger et al.   JOURNAL OF MAMMALOGY

Recent rodent models for Alzheimer’s disease: clinical implications and basic research

(2011) Nady Braidy et al.   JOURNAL OF NEURAL TRANSMISSION

Effects of low versus high frequencies of repetitive transcranial magnetic stimulation on cognitive function and cortical excitability in Alzheimer’s dementia

(2011) Mohamed A. Ahmed et al.   JOURNAL OF NEUROLOGY

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

(2011) Berislav V. Zlokovic   NATURE REVIEWS NEUROSCIENCE

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology

(2011) Karim Belarbi et al.   NEUROBIOLOGY OF DISEASE

Treadmill exercise prevents decline in spatial learning and memory in APP/PS1 transgenic mice through improvement of hippocampal long-term potentiation

(2010) Hui-li Liu et al.   BEHAVIOURAL BRAIN RESEARCH

Improved language performance in Alzheimer disease following brain stimulation

(2010) M. Cotelli et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Burrowing: A sensitive behavioural assay, tested in five species of laboratory rodents

(2009) R.M.J. Deacon   BEHAVIOURAL BRAIN RESEARCH

Brain-Derived Neurotrophic Factor Reduces Amyloidogenic Processing through Control of SORLA Gene Expression

(2009) M. Rohe et al.   JOURNAL OF NEUROSCIENCE

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

(2009) Clifford R Jack et al.   LANCET NEUROLOGY

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

(2009) Alan H Nagahara et al.   NATURE MEDICINE

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-Localization of Amyloid Beta and Tau Pathology in Alzheimer's Disease Synaptosomes

(2008) Jeffrey A. Fein et al.   AMERICAN JOURNAL OF PATHOLOGY

Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats

(2008) S. Arancibia et al.   NEUROBIOLOGY OF DISEASE

NGF and BDNF signaling control amyloidogenic route and A  production in hippocampal neurons

(2008) C. Matrone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA