A Community-Based Study Identifying Metabolic Biomarkers of Mild Cognitive Impairment and Alzheimer’s Disease Using Artificial Intelligence and Machine Learning

Diagnosis of Alzheimer's disease using universum support vector machine based recursive feature elimination (USVM-RFE)

(2020) B. Richhariya et al.   Biomedical Signal Processing and Control

Three plasma metabolites in elderly patients differentiate mild cognitive impairment and Alzheimer’s disease: a pilot study

(2019) Alana C. Costa et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Artificial intelligence and the analysis of multi-platform metabolomics data for the detection of intrauterine growth restriction

(2019) Ray Oliver Bahado-Singh et al.   PLoS One

Systemic and central nervous system metabolic alterations in Alzheimer’s disease

(2019) Vera van der Velpen et al.   Alzheimers Research & Therapy

The Differences of Serum Metabolites Between Patients With Early-Stage Alzheimer's Disease and Mild Cognitive Impairment

(2019) Wei-Chieh Weng et al.   Frontiers in Neurology

NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease

(2018) Clifford R. Jack et al.   Alzheimers & Dementia

Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson’s Disease Reveals Distinct Metabolic Profiles

(2018) Stewart F. Graham et al.   JOURNAL OF PROTEOME RESEARCH

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

(2018) Jasmine Chong et al.   NUCLEIC ACIDS RESEARCH

Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study

(2018) Vijay R. Varma et al.   PLOS MEDICINE

A Multi-Center Study of ACE and the Risk of Late-Onset Alzheimer's Disease

(2018) Olivia Belbin et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma and Brain Fatty Acid Profiles in Mild Cognitive Impairment and Alzheimer's Disease

(2018) Stephen C. Cunnane et al.   JOURNAL OF ALZHEIMERS DISEASE

NS-kNN: a modified k-nearest neighbors approach for imputing metabolomics data

(2018) Justin Y. Lee et al.   Metabolomics

Advances in developing novel therapeutic strategies for Alzheimer’s disease

(2018) Jiqing Cao et al.   Molecular Neurodegeneration

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

(2018) Harald Hampel et al.   Nature Reviews Neurology

Diagnostic Biomarkers of Alzheimer’s Disease as Identified in Saliva using 1H NMR-Based Metabolomics

(2017) Ali Yilmaz et al.   JOURNAL OF ALZHEIMERS DISEASE

Targeted Metabolic Profiling of Post-Mortem Brain from Infants Who Died from Sudden Infant Death Syndrome

(2017) Stewart F. Graham et al.   JOURNAL OF PROTEOME RESEARCH

Dementia prevention, intervention, and care

(2017) Gill Livingston et al.   LANCET

What success can teach us about failure: the plasma metabolome of older adults with superior memory and lessons for Alzheimer's disease

(2017) Mark Mapstone et al.   NEUROBIOLOGY OF AGING

Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration

(2017) Peter Schönfeld et al.   NEUROCHEMISTRY INTERNATIONAL

Integrated Proteomic and Metabolomic prediction of Term Preeclampsia

(2017) Ray Bahado-Singh et al.   Scientific Reports

Metabolic signatures of Huntington's disease (HD): 1 H NMR analysis of the polar metabolome in post-mortem human brain

(2016) Stewart F. Graham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Alzheimer's disease–like pathology has transient effects on the brain and blood metabolome

(2016) Xiaobei Pan et al.   NEUROBIOLOGY OF AGING

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Plasma 24-metabolite Panel Predicts Preclinical Transition to Clinical Stages of Alzheimer’s Disease

(2015) Massimo S. Fiandaca et al.   Frontiers in Neurology

Untargeted Metabolomic Analysis of Human Plasma Indicates Differentially Affected Polyamine and L-Arginine Metabolism in Mild Cognitive Impairment Subjects Converting to Alzheimer’s Disease

(2015) Stewart F. Graham et al.   PLoS One

Accurate, Fully-Automated NMR Spectral Profiling for Metabolomics

(2015) Siamak Ravanbakhsh et al.   PLoS One

The critical need for defining preclinical biomarkers in Alzheimer's disease

(2014) Massimo S. Fiandaca et al.   Alzheimers & Dementia

Mild cognitive impairment: a concept in evolution

(2014) R. C. Petersen et al.   JOURNAL OF INTERNAL MEDICINE

Plasma phospholipids identify antecedent memory impairment in older adults

(2014) Mark Mapstone et al.   NATURE MEDICINE

Amyloid β, Glutamate, Excitotoxicity in Alzheimer's Disease: Are We on the Right Track?

(2013) Zaira Esposito et al.   CNS Neuroscience & Therapeutics

A way forward for research on biomarkers for psychiatric disorders

(2013) Patricia Boksa   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Alterations in metabolic pathways and networks in Alzheimer’s disease

(2013) R Kaddurah-Daouk et al.   Translational Psychiatry

Comparing metabolomic and pathologic biomarkers alone and in combination for discriminating Alzheimer’s disease from normal cognitive aging

(2013) Alison A Motsinger-Reif et al.   Acta Neuropathologica Communications

Toward a Predictive Model of Alzheimer’s Disease Progression Using Capillary Electrophoresis–Mass Spectrometry Metabolomics

(2012) Clara Ibáñez et al.   ANALYTICAL CHEMISTRY

A support vector machine-recursive feature elimination feature selection method based on artificial contrast variables and mutual information

(2012) Xiaohui Lin et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

(2012) J. Xia et al.   NUCLEIC ACIDS RESEARCH

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Marilyn S. Albert et al.   Alzheimers & Dementia

Towards automatic metabolomic profiling of high-resolution one-dimensional proton NMR spectra

(2011) Pascal Mercier et al.   JOURNAL OF BIOMOLECULAR NMR

The Human Serum Metabolome

(2011) Nikolaos Psychogios et al.   PLoS One

Metabolomics in Early Alzheimer's Disease: Identification of Altered Plasma Sphingolipidome Using Shotgun Lipidomics

(2011) Xianlin Han et al.   PLoS One

Advances in metabolite identification

(2011) David S Wishart   Bioanalysis

Metabolomic changes in autopsy-confirmed Alzheimer's disease

(2010) Rima Kaddurah-Daouk et al.   Alzheimers & Dementia

Decision tree supported substructure prediction of metabolites from GC-MS profiles

(2010) Jan Hummel et al.   Metabolomics

Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies

(2009) A. J. Mitchell et al.   ACTA PSYCHIATRICA SCANDINAVICA

Detecting Dementia With the Mini-Mental State Examination in Highly Educated Individuals

(2008) Sid E. O’Bryant et al.   ARCHIVES OF NEUROLOGY

Metabolomics-based methods for early disease diagnostics

(2008) GA Nagana Gowda et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS