Yeast Translation Elongation Factor eIF5A Expression Is Regulated by Nutrient Availability through Different Signalling Pathways

The inhibition of eIF5A hypusination by GC7, a preconditioning protocol to prevent brain death‐induced renal injuries in a preclinical porcine kidney transplantation model

(2020) Sebastien Giraud et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Inhibition of eIF5A hypusination pathway as a new pharmacological target for stroke therapy

(2020) Miled Bourourou et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Eukaryotic translation initiation factor 5A in the pathogenesis of cancers (Review)

(2020) Liang Ning et al.   Oncology Letters

Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission

(2020) Dong Ma et al.   PLOS BIOLOGY

Iron Regulatory Mechanisms in Saccharomyces cerevisiae

(2020) Lucía Ramos-Alonso et al.   Frontiers in Microbiology

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

(2019) Daniel J. Puleston et al.   Cell Metabolism

Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast

(2019) Joseph Kunkel et al.   Nature Communications

Translation Elongation and Recoding in Eukaryotes

(2018) Thomas E. Dever et al.   Cold Spring Harbor Perspectives in Biology

Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency

(2018) Lucía Ramos-Alonso et al.   PLoS Genetics

Hypusine, a polyamine-derived amino acid critical for eukaryotic translation

(2018) Myung Hee Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A constitutive active allele of the transcription factor Msn2 mimicking low PKA activity dictates metabolic remodeling in yeast

(2018) Vera Pfanzagl et al.   MOLECULAR BIOLOGY OF THE CELL

Increased heme synthesis in yeast induces a metabolic switch from fermentation to respiration even under conditions of glucose repression

(2017) Tiantian Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

eIF5A Functions Globally in Translation Elongation and Termination

(2017) Anthony P. Schuller et al.   MOLECULAR CELL

eIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequences

(2017) Vicent Pelechano et al.   NUCLEIC ACIDS RESEARCH

Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins

(2017) Verónica Muñoz-Soriano et al.   Scientific Reports

Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer

(2016) Shima Nakanishi et al.   AMINO ACIDS

Eukaryotic translation initiation factor 5A2 promotes metabolic reprogramming in hepatocellular carcinoma cells

(2016) Ting-Ting Cao et al.   CARCINOGENESIS

Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect

(2016) Iñigo San-Millán et al.   CARCINOGENESIS

Alternative Start Codon Connects eIF5A to Mitochondria

(2016) Karina Danielle Pereira et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting eIF5A Hypusination Prevents Anoxic Cell Death through Mitochondrial Silencing and Improves Kidney Transplant Outcome

(2016) Nicolas Melis et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Msb2 is a Ste11 membrane concentrator required for full activation of the HOG pathway

(2015) Aurora Zuzuarregui et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The translation factor eIF5A and human cancer

(2015) Michael B. Mathews et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A

(2015) T. Miyake et al.   CLINICAL CANCER RESEARCH

The cytotoxic T cell proteome and its shaping by the kinase mTOR

(2015) Jens L Hukelmann et al.   NATURE IMMUNOLOGY

Snf1/AMPK promotes the formation of Kog1/Raptor-bodies to increase the activation threshold of TORC1 in budding yeast

(2015) James E Hughes Hallett et al.   eLife

Fertility and Polarized Cell Growth Depends on eIF5A for Translation of Polyproline-Rich Formins in Saccharomyces cerevisiae

(2014) Tianlu Li et al.   GENETICS

Targeting and plasticity of mitochondrial proteins revealed by proximity-specific ribosome profiling

(2014) C. C. Williams et al.   SCIENCE

eIF5A Promotes Translation of Polyproline Motifs

(2013) Erik Gutierrez et al.   MOLECULAR CELL

Nonsense-Mediated mRNA Decay Controls the Changes in Yeast Ribosomal Protein Pre-mRNAs Levels upon Osmotic Stress

(2013) Elena Garre et al.   PLoS One

Mitochondrial proteomics of nasopharyngeal carcinoma metastasis

(2012) Jianping Liu et al.   BMC Medical Genomics

Translational control of eIF5A in various diseases

(2011) Annette Kaiser   AMINO ACIDS

Doxorubicin Induces Apoptosis in H9c2 Cardiomyocytes: Role of Overexpressed Eukaryotic Translation Initiation Factor 5A

(2010) Xiao Tan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates

(2010) Sarah-Maria Fendt et al.   BMC Systems Biology

Apoptosis induction by eIF5A1 involves activation of the intrinsic mitochondrial pathway

(2010) Zhong Sun et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transcriptional Regulation in Yeast during Diauxic Shift and Stationary Phase

(2010) Luciano Galdieri et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Iron Regulation through the Back Door: Iron-Dependent Metabolite Levels Contribute to Transcriptional Adaptation to Iron Deprivation in Saccharomyces cerevisiae

(2009) Jessica Ihrig et al.   EUKARYOTIC CELL

Transcriptional regulation of nonfermentable carbon utilization in budding yeast

(2009) Bernard Turcotte et al.   FEMS YEAST RESEARCH

Glucose regulates transcription in yeast through a network of signaling pathways

(2009) Shadia Zaman et al.   Molecular Systems Biology

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

Cooperation of Two mRNA-Binding Proteins Drives Metabolic Adaptation to Iron Deficiency

(2008) Sergi Puig et al.   Cell Metabolism

Increased Respiration in thesch9ΔMutant Is Required for Increasing Chronological Life Span but Not Replicative Life Span

(2008) Hugo Lavoie et al.   EUKARYOTIC CELL

SNF1/AMPK pathways in yeast

(2007) Kristina Hedbacker   Frontiers in Bioscience-Landmark