Impact of Digestive Inflammatory Environment and Genipin Crosslinking on Immunomodulatory Capacity of Injectable Musculoskeletal Tissue Scaffold

Investigating the potential to deliver and maintain plasma and brain levels of a novel practically insoluble methuosis inducing anticancer agent 5-methoxy MOMIPP through an injectable in situ forming thermoresponsive hydrogel formulation

(2020) Frank Oppong et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Interleukin‐4‐loaded hydrogel scaffold regulates macrophages polarization to promote bone mesenchymal stem cells osteogenic differentiation via TGF‐β1/Smad pathway for repair of bone defect

(2020) Jiankang Zhang et al.   CELL PROLIFERATION

Genipin enhances the therapeutic effects of oxaliplatin by upregulating BIM in colorectal cancer

(2019) Bo Ram Kim et al.   MOLECULAR CANCER THERAPEUTICS

Sustained Local Delivery of Diclofenac from Three-Dimensional Ultrafine Fibrous Protein Scaffolds with Ultrahigh Drug Loading Capacity

(2019) S. M. Kamrul Hasan et al.   Nanomaterials

Programmed Release of Multimodal, Cross-Linked Vascular Endothelial Growth Factor and Heparin Layers on Electrospun Polycaprolactone Vascular Grafts

(2019) Dongfang Wang et al.   ACS Applied Materials & Interfaces

Genipin crosslinked bioactive collagen/chitosan/hyaluronic acid injectable hydrogels structurally amended via covalent attachment of surface-modified silica particles

(2019) Joanna Lewandowska-Łańcucka et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Dual Crosslinked Collagen/Chitosan Film for Potential Biomedical Applications

(2019) Rushita Shah et al.   Polymers

Biomimetic sponges for regeneration of skeletal muscle following trauma

(2018) Gabriel J. Haas et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Incorporation of the Amniotic Membrane as an Immunomodulatory Design Element in Collagen Scaffolds for Tendon Repair

(2018) Rebecca A. Hortensius et al.   ACS Biomaterials-Science & Engineering

Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells

(2017) Lidia Bosurgi et al.   SCIENCE

CD163 as a marker of M2 macrophage, contribute to predict aggressiveness and prognosis of Kazakh esophageal squamous cell carcinoma

(2017) Jian Ming Hu et al.   Oncotarget

Design and Validation of Equiaxial Mechanical Strain Platform, EQUicycler, for 3D Tissue Engineered Constructs

(2017) Mostafa Elsaadany et al.   Biomed Research International

Effect of Uniaxial Tensile Cyclic Loading Regimes on Matrix Organization and Tenogenic Differentiation of Adipose-Derived Stem Cells Encapsulated within 3D Collagen Scaffolds

(2017) Gayathri Subramanian et al.   Stem Cells International

Thermo-responsive cell culture carrier: Effects on macrophage functionality and detachment efficiency

(2017) Knut Rennert et al.   Journal of Tissue Engineering

Equiaxial Strain Modulates Adipose-derived Stem Cell Differentiation within 3D Biphasic Scaffolds towards Annulus Fibrosus

(2017) Mostafa Elsaadany et al.   Scientific Reports

Immuno-Informed 3D Silk Biomaterials for Tailoring Biological Responses

(2016) Manishekhar Kumar et al.   ACS Applied Materials & Interfaces

IL-4 Release from a Biomimetic Scaffold for the Temporally Controlled Modulation of Macrophage Response

(2016) Silvia Minardi et al.   ANNALS OF BIOMEDICAL ENGINEERING

Influence of collagen concentration and glutaraldehyde on collagen-based scaffold properties

(2016) V. Perez-Puyana et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma

(2016) Hor-Yue Tan et al.   Oncotarget

Identification of Differentially Expressed Long Non-coding RNAs in Polarized Macrophages

(2016) Zikun Huang et al.   Scientific Reports

Biomimetic collagenous scaffold to tune inflammation by targeting macrophages

(2016) Francesca Taraballi et al.   Journal of Tissue Engineering

Effects of cranberry extracts on gene expression in THP-1 cells

(2016) Daniel B. Hannon et al.   Food Science & Nutrition

Phenotypic, Functional, and Plasticity Features of Classical and Alternatively Activated Human Macrophages

(2015) Abdullah A. Tarique et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Optimization of the transfection of human THP-1 macrophages by application of Nunc UpCell technology

(2015) Marten B. Maeß et al.   ANALYTICAL BIOCHEMISTRY

Controlled release of cytokines using silk-biomaterials for macrophage polarization

(2015) Andrew R.D. Reeves et al.   BIOMATERIALS

Sequential delivery of immunomodulatory cytokines to facilitate the M1-to-M2 transition of macrophages and enhance vascularization of bone scaffolds

(2015) Kara L. Spiller et al.   BIOMATERIALS

Genipin suppresses NLRP3 inflammasome activation through uncoupling protein-2

(2015) Venugopal Rajanbabu et al.   CELLULAR IMMUNOLOGY

Formulation and Stability of Cytokine Therapeutics

(2015) Tiina Lipiäinen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Nanofibrous yet injectable polycaprolactone-collagen bone tissue scaffold with osteoprogenitor cells and controlled release of bone morphogenetic protein-2

(2015) Gayathri Subramanian et al.   Materials Science & Engineering C-Materials for Biological Applications

Matrix remodeling by MMPs during wound repair

(2015) Maryam G. Rohani et al.   MATRIX BIOLOGY

Diffusion–reaction models of genipin incorporation into fibrin networks

(2015) Chi Ninh et al.   Journal of Materials Chemistry B

Metalloproteinases and Wound Healing

(2015) Matthew P. Caley et al.   Advances in Wound Care

The Recognition of Collagen and Triple-helical Toolkit Peptides by MMP-13

(2014) Joanna-Marie Howes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In situ osteoblast mineralization mediates post-injection mechanical properties of osteoconductive material

(2014) Callan Bialorucki et al.   Journal of the Mechanical Behavior of Biomedical Materials

Structural and Biochemical Modification of a Collagen Scaffold to Selectively Enhance MSC Tenogenic, Chondrogenic, and Osteogenic Differentiation

(2014) Steven R. Caliari et al.   Advanced Healthcare Materials

Effects of crosslinking on the mechanical properties, drug release and cytocompatibility of protein polymers

(2013) Adam W. Martinez et al.   Acta Biomaterialia

Polycaprolactone nanofiber interspersed collagen type-I scaffold for bone regeneration: a unique injectable osteogenic scaffold

(2013) Nuray Baylan et al.   Biomedical Materials

Tendons – time to revisit inflammation

(2013) Jonathan D Rees et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T

(2013) Ulrich Eckhard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interleukin (IL)-4 induces production of cytokine-induced neutrophil chemoattractants (CINCs) and intercellular adhesion molecule (ICAM)-1 in lungs of asthmatic rats

(2013) Ya-li Guo et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Scleraxis-Overexpressed Human Embryonic Stem Cell–Derived Mesenchymal Stem Cells for Tendon Tissue Engineering with Knitted Silk-Collagen Scaffold

(2013) Xiao Chen et al.   TISSUE ENGINEERING PART A

Enhanced physicochemical properties of collagen by using EDC/NHS-crosslinking

(2012) CHUNRONG YANG   BULLETIN OF MATERIALS SCIENCE

Autophagy in Premature Senescent Cells Is Activated via AMPK Pathway

(2012) Liujing Guo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Serum Albumin Prevents Protein Aggregation and Amyloid Formation and Retains Chaperone-like Activity in the Presence of Physiological Ligands

(2012) Thomas E. Finn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genipin crosslinking elevates the strength of electrochemically aligned collagen to the level of tendons

(2012) Jorge Alfredo Uquillas et al.   Journal of the Mechanical Behavior of Biomedical Materials

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(2012) Tae-Hoon Kim et al.   MOLECULAR MEDICINE

Anticalcification effects of decellularization, solvent, and detoxification treatment for genipin and glutaraldehyde fixation of bovine pericardium

(2011) H.-G. Lim et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

The chemokine CCL18 causes maturation of cultured monocytes to macrophages in the M2 spectrum

(2011) Ingrid U. Schraufstatter et al.   IMMUNOLOGY

Genipin-Cross-linked Electrospun Collagen Fibers

(2011) Mina Mekhail et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Enhanced Cellular Functions on Polycaprolactone Tissue Scaffolds by O2 Plasma Surface Modification

(2011) Eda D. Yildirim et al.   Plasma Processes and Polymers

The requirement of zinc and calcium ions for functional MMP activity in demineralized dentin matrices

(2010) Arzu Tezvergil-Mutluay et al.   DENTAL MATERIALS

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Slow and sustained release of active cytokines from self-assembling peptide scaffolds

(2010) Fabrizio Gelain et al.   JOURNAL OF CONTROLLED RELEASE

Neuroprotective Action of Genipin on Tunicamycin-Induced Cytotoxicity in Neuro2a Cells

(2009) Masayuki Tanaka et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Effects of the Constituents of Gardenia Fructus on Prostaglandin and NO Production

(2009) Hyun Lim et al.   Biomolecules & Therapeutics

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

The antioxidant properties of serum albumin

(2008) Marjolaine Roche et al.   FEBS LETTERS

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE

Inhibitory Potencies of Several Iridoids on Cyclooxygenase-1, Cyclooxygnase-2 Enzymes Activities, Tumor Necrosis Factor-α and Nitric Oxide ProductionIn Vitro

(2007) Kyoung Sik Park et al.   Evidence-based Complementary and Alternative Medicine