Single Administration of the T-Type Calcium Channel Enhancer SAK3 Reduces Oxidative Stress and Improves Cognition in Olfactory Bulbectomized Mice

Oral glutathione administration inhibits the oxidative stress and the inflammatory responses in AppNL−G-F/NL−G-F knock-in mice

(2020) Hisanao Izumi et al.   NEUROPHARMACOLOGY

Neuroprotective effects of protein tyrosine phosphatase 1B inhibitor on cerebral ischemia/reperfusion in mice

(2018) Meiling Sun et al.   BRAIN RESEARCH

T-type calcium channel enhancer SAK3 produces anti-depressant-like effects by promoting adult hippocampal neurogenesis in olfactory bulbectomized mice

(2018) Jing Xu et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The Disease-modifying Drug Candidate, SAK3 Improves Cognitive Impairment and Inhibits Amyloid beta Deposition in App Knock-in Mice

(2018) Hisanao Izumi et al.   NEUROSCIENCE

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Alzheimer’s disease hypothesis and related therapies

(2018) Xiaoguang Du et al.   Translational Neurodegeneration

The Diverse Roles of Microglia in the Neurodegenerative Aspects of Central Nervous System (CNS) Autoimmunity

(2017) Kaitlyn Thompson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The T-type calcium channel enhancer SAK3 inhibits neuronal death following transient brain ischemia via nicotinic acetylcholine receptor stimulation

(2017) Yasushi Yabuki et al.   NEUROCHEMISTRY INTERNATIONAL

Pharmacological properties of SAK3, a novel T-type voltage-gated Ca 2+ channel enhancer

(2017) Yasushi Yabuki et al.   NEUROPHARMACOLOGY

Regulatory factor X1 depresses ApoE-dependent Aβ uptake by miRNA-124 in microglial response to oxidative stress

(2017) Chen-Zhuo Feng et al.   NEUROSCIENCE

Silymarin ameliorates experimentally induced depressive like behavior in rats: Involvement of hippocampal BDNF signaling, inflammatory cytokines and oxidative stress response

(2017) Vishnu N. Thakare et al.   PHYSIOLOGY & BEHAVIOR

Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts

(2016) Alessandra Pecorelli et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Immunization Against Specific Fragments of Neurotrophin p75 Receptor Protects Forebrain Cholinergic Neurons in the Olfactory Bulbectomized Mice

(2016) Natalia Bobkova et al.   JOURNAL OF ALZHEIMERS DISEASE

Live Imaging of Immune Responses in Experimental Models of Multiple Sclerosis

(2016) Barbara Rossi et al.   Frontiers in Immunology

Targeting of CaV3.2 T-type calcium channels in peripheral sensory neurons for the treatment of painful diabetic neuropathy

(2014) Slobodan M. Todorovic et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

T-type calcium channels blockers as new tools in cancer therapies

(2014) Barbara Dziegielewska et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Chronic Neuroinflammation in Alzheimer’s Disease: New Perspectives on Animal Models and Promising Candidate Drugs

(2014) Christopher Millington et al.   Biomed Research International

Forward Suppression in the Auditory Cortex Is Caused by the Cav3.1 Calcium Channel-Mediated Switch from Bursting to Tonic Firing at Thalamocortical Projections

(2013) I. T. Bayazitov et al.   JOURNAL OF NEUROSCIENCE

The Novel Cognitive Enhancer ST101 Enhances Acetylcholine Release in Mouse Dorsal Hippocampus Through T-type Voltage-Gated Calcium Channel Stimulation

(2013) Yui Yamamoto et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Oral administration of glutathione improves memory deficits following transient brain ischemia by reducing brain oxidative stress

(2013) Y. Yabuki et al.   NEUROSCIENCE

The Role of Microglia in the Healthy Brain

(2011) M.-E. Tremblay et al.   JOURNAL OF NEUROSCIENCE

Effect of 17β-estradiol on olfactory bulbectomy-induced oxidative stress and behavioral changes in rats

(2011) Isaac Tunez   Neuropsychiatric Disease and Treatment

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Donepezil-induced Neuroprotection of Acetylcholinergic Neurons in Olfactory Bulbectomized Mice

(2010) Yui YAMAMOTO et al.   YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN

Mitochondrial ATP-Synthase in the Entorhinal Cortex Is a Target of Oxidative Stress at Stages I/II of Alzheimer's Disease Pathology

(2009) Beatrice Terni et al.   BRAIN PATHOLOGY

Protective effect of nicotine on oxidative and cell damage in rats with depression induced by olfactory bulbectomy

(2009) Isaac Túnez et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Review: A review of the use of zonisamide in Parkinson’s disease

(2009) Pedro Emilio Bermejo et al.   Therapeutic Advances in Neurological Disorders

Reviews: Current Concepts in Alzheimer's Disease: A Multidisciplinary Review

(2008) Ludovico Minati et al.   American Journal of Alzheimers Disease and Other Dementias

Activation of nicotinic acetylcholine receptor prevents the production of reactive oxygen species in fibrillar β amyloid peptide (1-42)-stimulated microglia

(2008) Ju Hyun Moon et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Neurodegeneration in multiple sclerosis: The role of oxidative stress and excitotoxicity

(2008) R.E. Gonsette   JOURNAL OF THE NEUROLOGICAL SCIENCES