Gangliosides in Podocyte Biology and Disease

Targeting glycosphingolipid metabolism as a potential therapeutic approach for treating disease in female MRL/lpr lupus mice

(2020) Tamara K. Nowling et al.   PLoS One

Podocytopathy and Nephrotic Syndrome in Mice with Podocyte-Specific Deletion of the Asah1 Gene

(2020) Guangbi Li et al.   AMERICAN JOURNAL OF PATHOLOGY

APOL1 polymorphism modulates sphingolipid profile of human podocytes

(2020) Manuela Valsecchi et al.   GLYCOCONJUGATE JOURNAL

Metabolism of Glycosphingolipids and Their Role in the Pathophysiology of Lysosomal Storage Disorders

(2020) Alex E. Ryckman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Kidney Lipidomics by Mass Spectrometry Imaging: A Focus on the Glomerulus

(2019) Imane Abbas et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

CMIP is a negative regulator of T cell signaling

(2019) Julie Oniszczuk et al.   Cellular & Molecular Immunology

Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy

(2018) Sun Ryoung Choi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications

(2017) Andreas R. Janecke et al.   HUMAN MUTATION

Sphingosine-1-phosphate lyase mutations cause primary adrenal insufficiency and steroid-resistant nephrotic syndrome

(2017) Rathi Prasad et al.   JOURNAL OF CLINICAL INVESTIGATION

Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency

(2017) Svjetlana Lovric et al.   JOURNAL OF CLINICAL INVESTIGATION

Electrospray Ionization Ion Mobility Mass Spectrometry of Human Brain Gangliosides

(2016) Mirela Sarbu et al.   ANALYTICAL CHEMISTRY

Distinct selectivity of gangliosides required for CD4 + T and CD8 + T cell activation

(2015) Jin-ichi Inokuchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Lipidomics: An Evolving Discipline in Molecular Sciences

(2015) Giuseppe Astarita et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Monitoring Diabetic Nephropathy by Circulating Gangliosides

(2015) Corina Daniela Ene et al.   JOURNAL OF IMMUNOASSAY & IMMUNOCHEMISTRY

The Missing Link - Likely Pathogenetic Role of GM3 and Other Gangliosides in the Development of Diabetic Nephropathy

(2015) Igor Vukovic et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation

(2015) Jens Schümann et al.   TOXICOLOGIC PATHOLOGY

Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages

(2014) A. Tomin et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Histochemical and immunoelectron microscopic analysis of ganglioside GM3 in human kidney

(2014) Tetsuya Kaneko et al.   Clinical and Experimental Nephrology

GM3 and diabetes

(2014) Jin-ichi Inokuchi   GLYCOCONJUGATE JOURNAL

Diabetic nephropathy induces alterations in the glomerular and tubule lipid profiles

(2014) Kerri J. Grove et al.   JOURNAL OF LIPID RESEARCH

Renal Glycosphingolipid Metabolism Is Dysfunctional in Lupus Nephritis

(2014) T. K. Nowling et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sphingomyelinase-Like Phosphodiesterase 3b Expression Levels Determine Podocyte Injury Phenotypes in Glomerular Disease

(2014) T.-H. Yoo et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Lipid biology of the podocyte—new perspectives offer new opportunities

(2014) Alessia Fornoni et al.   Nature Reviews Nephrology

Immunopathogenesis of idiopathic nephrotic syndrome with relapse

(2014) Djillali Sahali et al.   Seminars in Immunopathology

Podocyte Pathology and Nephropathy – Sphingolipids in Glomerular Diseases

(2014) Sandra Merscher et al.   Frontiers in Endocrinology

NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex

(2013) Eun Young Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Renal distribution of ganglioside GM3 in rat models of types 1 and 2 diabetes

(2013) Anela Novak et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

How Do Gangliosides Regulate RTKs Signaling?

(2013) Sylvain Julien et al.   Cells

Soluble FLT1 Binds Lipid Microdomains in Podocytes to Control Cell Morphology and Glomerular Barrier Function

(2012) Jing Jin et al.   CELL

Heterogeneity of gangliosides among T cell subsets

(2012) Jin-ichi Inokuchi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease

(2012) Thomas A. Natoli et al.   HUMAN MOLECULAR GENETICS

Anti-ganglioside antibodies in patients with systemic lupus erythematosus and neurological manifestations

(2012) M Labrador-Horrillo et al.   LUPUS

Invariant Natural Killer T Cell Agonist Modulates Experimental Focal and Segmental Glomerulosclerosis

(2012) Rafael L. Pereira et al.   PLoS One

Acid Sphingomyelinase Gene Knockout Ameliorates Hyperhomocysteinemic Glomerular Injury in Mice Lacking Cystathionine-β-Synthase

(2012) Krishna M. Boini et al.   PLoS One

CD4 and CD8 T cells require different membrane gangliosides for activation

(2012) M. Nagafuku et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

(2011) A. Fornoni et al.   Science Translational Medicine

Gangliosides' analysis by MALDI-ion mobility MS

(2010) Shelley N. Jackson et al.   ANALYST

Increased Expression of Ganglioside GM1 in Peripheral CD4+ T Cells Correlates Soluble Form of CD30 in Systemic Lupus Erythematosus Patients

(2010) Lingli Dong et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Progressive podocyte injury and globotriaosylceramide (GL-3) accumulation in young patients with Fabry disease

(2010) Behzad Najafian et al.   KIDNEY INTERNATIONAL

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

c-mip Impairs Podocyte Proximal Signaling and Induces Heavy Proteinuria

(2010) S. y. Zhang et al.   Science Signaling

Lipid-Protein Interactions along the Slit Diaphragm of Podocytes

(2009) B. Schermer et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mice lacking ganglioside GM3 synthase exhibit complete hearing loss due to selective degeneration of the organ of Corti

(2009) M. Yoshikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thin layer chromatography of gangliosides

(2008) Federica Scandroglio et al.   GLYCOCONJUGATE JOURNAL

Renal gangliosides are involved in lead intoxication

(2007) Rossana Pérez Aguilar et al.   JOURNAL OF APPLIED TOXICOLOGY