A Role for Caveolin-3 in the Pathogenesis of Muscular Dystrophies

The role of the dystrophin glycoprotein complex on the neuromuscular system

(2020) Dina C Belhasan et al.   NEUROSCIENCE LETTERS

Characterization of Zika Virus Endocytic Pathways in Human Glioblastoma Cells

(2020) Mei Li et al.   Frontiers in Microbiology

Caveolin‐3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function

(2020) Dinesh S. Shah et al.   Journal of Cachexia Sarcopenia and Muscle

A novel missense mutation in CAV3 gene in an Italian family with persistent hyperCKemia, myalgia and hypercholesterolemia: Double-trouble

(2020) Giorgia Bruno et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Arhgef5 Binds α-Dystrobrevin 1 and Regulates Neuromuscular Junction Integrity

(2020) Krzysztof M. Bernadzki et al.   Frontiers in Molecular Neuroscience

Dystrophy-associated caveolin-3 mutations reveal that caveolae couple IL6/STAT3 signaling with mechanosensing in human muscle cells

(2019) Melissa Dewulf et al.   Nature Communications

mTORC1 and PKB/Akt control the muscle response to denervation by regulating autophagy and HDAC4

(2019) Perrine Castets et al.   Nature Communications

Caveolin 3-dependent loss of t-tubular I Ca during hypertrophy and heart failure in mice

(2018) Simon M. Bryant et al.   EXPERIMENTAL PHYSIOLOGY

creat229 th ENMC international workshop: Limb girdle muscular dystrophies – nomenclature and reformed classification, 17-19 March 2017, Naarden, The Netherlands

(2018) Volker Straub et al.   NEUROMUSCULAR DISORDERS

Propofol Provides Cardiac Protection by Suppressing the Proteasome Degradation of Caveolin-3 in Ischemic/Reperfused Rat Hearts

(2017) Afang Zhu et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Caveolin 3 deficiency myopathy associated with dyslipidemia: Treatment challenges and possible pathophysiological association

(2017) Daiana Ibarretxe et al.   Journal of Clinical Lipidology

Liprin-α-1 is a novel component of the murine neuromuscular junction and is involved in the organization of the postsynaptic machinery

(2017) Krzysztof M. Bernadzki et al.   Scientific Reports

Caveolin-3 promotes glycometabolism, growth and proliferation in muscle cells

(2017) Lina Shang et al.   PLoS One

Caveolin-3 plays a critical role in autophagy after ischemia-reperfusion

(2016) Adam Kassan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction

(2016) Jacinthe Gingras et al.   JOURNAL OF CELL SCIENCE

CAV3 mutation in a patient with transient hyperCKemia and myalgia

(2016) Anna Macias et al.   Neurologia i Neurochirurgia Polska

Mutation in the caveolin-3 gene causes asymmetrical distal myopathy

(2016) Juanjuan Chen et al.   NEUROPATHOLOGY

Absence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy

(2016) David G. Allen et al.   PHYSIOLOGICAL REVIEWS

Caveolae: One Function or Many?

(2016) Jade P.X. Cheng et al.   TRENDS IN CELL BIOLOGY

Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice

(2016) Aleix Sala-Vila et al.   Scientific Reports

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

(2015) Jade P.X. Cheng et al.   JOURNAL OF CELL BIOLOGY

The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle

(2015) Harriet P. Lo et al.   JOURNAL OF CELL BIOLOGY

Prevention of cardiomyopathy in Duchenne muscular dystrophy

(2015) Corrado Angelini   LANCET NEUROLOGY

High-density lipoproteins as modulators of endothelial cell functions: alterations in patients with coronary artery disease

(2014) A. Kratzer et al.   CARDIOVASCULAR RESEARCH

High-Density Lipoprotein and Atherosclerosis Regression

(2014) Jonathan E. Feig et al.   CIRCULATION RESEARCH

Dependence of Cardiac Transverse Tubules on the BAR Domain Protein Amphiphysin II (BIN-1)

(2014) Jessica L. Caldwell et al.   CIRCULATION RESEARCH

Regulation of intracellular signaling and function by caveolin

(2014) Heidi N. Fridolfsson et al.   FASEB JOURNAL

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae

(2014) Yoshimitsu Kanai et al.   JOURNAL OF CELL BIOLOGY

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

(2014) TingTing Hong et al.   NATURE MEDICINE

MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by  1-adrenergic receptors

(2014) T. Ogata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Description of a utrophin associated protein complex in lipid raft domains of human artery smooth muscle cells

(2013) Carlos Palma-Flores et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Caveolin-3 regulates compartmentation of cardiomyocyte beta2-adrenergic receptor-mediated cAMP signaling

(2013) Peter T. Wright et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cholesterol Levels and Risk of Hemorrhagic Stroke

(2013) Xiang Wang et al.   STROKE

Caveolae internalization repairs wounded cells and muscle fibers

(2013) Matthias Corrotte et al.   eLife

Cavin-3 dictates the balance between ERK and Akt signaling

(2013) Victor J Hernandez et al.   eLife

Where the endoplasmic reticulum and the mitochondrion tie the knot: The mitochondria-associated membrane (MAM)

(2012) Arun Raturi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure-Based Reassessment of the Caveolin Signaling Model: Do Caveolae Regulate Signaling through Caveolin-Protein Interactions?

(2012) Brett M. Collins et al.   DEVELOPMENTAL CELL

Intestinal Microbiota Determine Severity of Myocardial Infarction in Rats

(2012) Kieran McCafferty et al.   FASEB JOURNAL

Mitochondria-localized caveolin in adaptation to cellular stress and injury

(2012) Heidi N. Fridolfsson et al.   FASEB JOURNAL

Characterization of the Molecular Architecture of Human Caveolin-3 and Interaction with the Skeletal Muscle Ryanodine Receptor

(2012) Gareth Whiteley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction of α-Catulin with Dystrobrevin Contributes to Integrity of Dystrophin Complex in Muscle

(2012) Hyun J. Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rippling muscle disease and facioscapulohumeral dystrophy-like phenotype in a patient carrying a heterozygous CAV3 T78M mutation and a D4Z4 partial deletion: Further evidence for “double trouble” overlapping syndromes

(2012) Giulia Ricci et al.   NEUROMUSCULAR DISORDERS

Structural Characterization of the Caveolin Scaffolding Domain in Association with Cholesterol-Rich Membranes

(2011) Cody L. Hoop et al.   BIOCHEMISTRY

Agrin triggers the clustering of raft-associated acetylcholine receptors through actin cytoskeleton reorganization

(2011) Annie Cartaud et al.   BIOLOGY OF THE CELL

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

PKCθ signaling is required for myoblast fusion by regulating the expression of caveolin-3 and β1D integrin upstream focal adhesion kinase

(2011) Luca Madaro et al.   MOLECULAR BIOLOGY OF THE CELL

Mosaic caveolin-3 expression in acquired rippling muscle disease without evidence of myasthenia gravis or acetylcholine receptor autoantibodies

(2011) Harriet P. Lo et al.   NEUROMUSCULAR DISORDERS

Role of Caveolae in Cardiac Protection

(2011) David M. Roth et al.   PEDIATRIC CARDIOLOGY

The Importance of Size

(2011) Christian H. Riedel et al.   STROKE

T-tubule biogenesis and triad formation in skeletal muscle and implication in human diseases

(2011) Lama Al-Qusairi et al.   Skeletal Muscle

Molecular mechanisms in evolutionary cardiology failure

(2010) Bernard Swynghedauw et al.   Annals of the New York Academy of Sciences

Functional role of TASK-1 in the heart: studies in TASK-1-deficient mice show prolonged cardiac repolarization and reduced heart rate variability

(2010) Birgit C. Donner et al.   BASIC RESEARCH IN CARDIOLOGY

Reversal of Cancer Cachexia and Muscle Wasting by ActRIIB Antagonism Leads to Prolonged Survival

(2010) Xiaolan Zhou et al.   CELL

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Targeted Deletion of the Extracellular Signal-Regulated Protein Kinase 5 Attenuates Hypertrophic Response and Promotes Pressure Overload–Induced Apoptosis in the Heart

(2010) Tomomi E. Kimura et al.   CIRCULATION RESEARCH

Partition profile of the nicotinic acetylcholine receptor in lipid domains upon reconstitution

(2010) Vicente Bermúdez et al.   JOURNAL OF LIPID RESEARCH

Membrane Fatty Acid Transporters as Regulators of Lipid Metabolism: Implications for Metabolic Disease

(2010) Jan F. C. Glatz et al.   PHYSIOLOGICAL REVIEWS

Lipid Rafts As a Membrane-Organizing Principle

(2010) D. Lingwood et al.   SCIENCE

Muscular dystrophy begins early in embryonic development deriving from stem cell loss and disrupted skeletal muscle formation

(2009) D. Merrick et al.   Disease Models & Mechanisms

SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function

(2009) Kerrie-Ann McMahon et al.   EMBO JOURNAL

Membrane Repair Defects in Muscular Dystrophy Are Linked to Altered Interaction between MG53, Caveolin-3, and Dysferlin

(2009) Chuanxi Cai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

(2009) Michele Bastiani et al.   JOURNAL OF CELL BIOLOGY

Focal Adhesion Kinase Signaling Regulates the Expression of Caveolin 3 and β1 Integrin, Genes Essential for Normal Myoblast Fusion

(2009) Navaline L. Quach et al.   MOLECULAR BIOLOGY OF THE CELL

Caveolin-3 Promotes Nicotinic Acetylcholine Receptor Clustering and Regulates Neuromuscular Junction Activity

(2009) Michael Hezel et al.   MOLECULAR BIOLOGY OF THE CELL

The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse

(2009) Gonneke S. K. Pilgram et al.   MOLECULAR NEUROBIOLOGY

SDPR induces membrane curvature and functions in the formation of caveolae

(2009) Carsten G. Hansen et al.   NATURE CELL BIOLOGY

Rippling muscle disease and cardiomyopathy associated with a mutation in the CAV3 gene

(2009) Michela Catteruccia et al.   NEUROMUSCULAR DISORDERS

A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique

(2009) A. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caveolae, ion channels and cardiac arrhythmias

(2009) Ravi C. Balijepalli et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Hydrophobic and Basic Domains Target Proteins to Lipid Droplets

(2009) Mercedes Ingelmo-Torres et al.   TRAFFIC

Cardiac-Specific Overexpression of Caveolin-3 Induces Endogenous Cardiac Protection by Mimicking Ischemic Preconditioning

(2008) Yasuo M. Tsutsumi et al.   CIRCULATION

Evolutionary analysis and molecular dissection of caveola biogenesis

(2008) M. Kirkham et al.   JOURNAL OF CELL SCIENCE

Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy

(2008) C. A. Kim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Caveolin-3 T78M and T78K missense mutations lead to different phenotypes in vivo and in vitro

(2008) Monica Traverso et al.   LABORATORY INVESTIGATION

MG53 nucleates assembly of cell membrane repair machinery

(2008) Chuanxi Cai et al.   NATURE CELL BIOLOGY

The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

(2008) Sven G. Meuth et al.   NEUROBIOLOGY OF DISEASE

Molecular pathology and enzyme processing in various phenotypes of acid maltase deficiency

(2008) A. C. Nascimbeni et al.   NEUROLOGY

High-Resolution 3D Quantitative Analysis of Caveolar Ultrastructure and Caveola–Cytoskeleton Interactions

(2008) Tobias Richter et al.   TRAFFIC