Citrullination-Resistant LL-37 Is a Potent Antimicrobial Agent in the Inflammatory Environment High in Arginine Deiminase Activity

Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties

(2020) Salma Al-Adwani et al.   Scientific Reports

Triggering NETosis via protease-activated receptor (PAR)-2 signaling as a mechanism of hijacking neutrophils function for pathogen benefits

(2019) Danuta Bryzek et al.   PLoS Pathogens

Homoarginine Supplementation Prevents Left Ventricular Dilatation and Preserves Systolic Function in a Model of Coronary Artery Disease

(2019) Roman N. Rodionov et al.   Journal of the American Heart Association

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA

(2018) Alicia Wong et al.   JOURNAL OF IMMUNOLOGY

Sharpening Host Defenses during Infection: Proteases Cut to the Chase

(2017) Natalie C. Marshall et al.   MOLECULAR & CELLULAR PROTEOMICS

Carbamylated LL-37 as a modulator of the immune response

(2016) Catalin Koro et al.   Innate Immunity

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

(2015) Huw D Lewis et al.   Nature Chemical Biology

The Host Defence Peptide LL-37 is Susceptible to Proteolytic Degradation by Wound Fluid Isolated from Foot Ulcers of Diabetic Patients

(2014) Maelíosa T. C. McCrudden et al.   International Journal of Peptide Research and Therapeutics

Citrullination Alters Immunomodulatory Function of LL-37 Essential for Prevention of Endotoxin-Induced Sepsis

(2014) J. Koziel et al.   JOURNAL OF IMMUNOLOGY

Solid-phase N-terminal peptide enrichment study by optimizing trypsin proteolysis on homoarginine-modified proteins by mass spectrometry

(2014) Saiful M. Chowdhury et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized, placebo-controlled clinical trial

(2014) Alvar Grönberg et al.   WOUND REPAIR AND REGENERATION

Neutrophil extracellular traps as a new paradigm in innate immunity: friend or foe?

(2013) Paul R. Cooper et al.   PERIODONTOLOGY 2000

Activation of PAD4 in NET formation

(2012) Amanda S. Rohrbach et al.   Frontiers in Immunology

Peptidylarginine Deiminases Present in the Airways during Tobacco Smoking and Inflammation Can Citrullinate the Host Defense Peptide LL-37, Resulting in Altered Activities

(2011) Ola Kilsgård et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation

(2009) Yanming Wang et al.   JOURNAL OF CELL BIOLOGY

Phagocytosis of Staphylococcus aureus by Macrophages Exerts Cytoprotective Effects Manifested by the Upregulation of Antiapoptotic Factors

(2009) Joanna Koziel et al.   PLoS One