Enhancing the catalytic activity of a GH5 processive endoglucanase from Bacillus subtilis BS-5 by site-directed mutagenesis

Structural changes induced by substitution of amino acid 129 in the coat protein of Cucumber mosaic virus

(2020) Vijay Kumar Bhardwaj et al.   GENOMICS

A new insight into protein-protein interactions and the effect of conformational alterations in PCNA

(2020) Vijay Kumar Bhardwaj et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Structural based study to identify new potential inhibitors for dual specificity tyrosine-phosphorylation- regulated kinase

(2020) Vijay Kumar Bhardwaj et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Discovery and in silico evaluation of aminoarylbenzosuberene molecules as novel checkpoint kinase 1 inhibitor determinants

(2020) Rahul Singh et al.   GENOMICS

Biotransformation of lignocellulosic biomass into industrially relevant products with the aid of fungi-derived lignocellulolytic enzymes

(2020) Sara Saldarriaga-Hernández et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Improving the thermostability of a thermostable endoglucanase from Chaetomium thermophilum by engineering the conserved noncatalytic residue and N-glycosylation site

(2020) Chao Han et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Computational investigation on effect of mutations in PCNA resulting in structural perturbations and inhibition of mismatch repair pathway

(2019) Vijay Bhardwaj et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Aromatic residues surrounding the active site tunnel of TfCel48A influence activity, processivity, and synergistic interactions with other cellulases

(2019) Kathleen L. Hefferon et al.   BIOTECHNOLOGY AND BIOENGINEERING

The dissociation mechanism of processive cellulases

(2019) Josh V. Vermaas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate binding in the processive cellulase Cel7A: Transition state of complexation and roles of conserved tryptophan residues

(2019) Nanna Røjel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural analogues inhibiting selective cyclin-dependent kinase protein isoforms: a computational perspective

(2019) Rahul Singh et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Elimination of bitter-off taste of stevioside through structure modification and computational interventions

(2019) Vijay Bhardwaj et al.   JOURNAL OF THEORETICAL BIOLOGY

Processive Degradation of Crystalline Cellulose by a Multimodular Endoglucanase via a Wirewalking Mode

(2018) Kun-Di Zhang et al.   BIOMACROMOLECULES

Truncation of the processive Cel5A of Thermotoga maritima results in soluble expression and several fold increase in activity

(2018) Abdul Basit et al.   BIOTECHNOLOGY AND BIOENGINEERING

Enhancing the catalytic activity of a novel GH5 cellulase GtCel5 from Gloeophyllum trabeum CBS 900.73 by site-directed mutagenesis on loop 6

(2018) Fei Zheng et al.   Biotechnology for Biofuels

Processivity and enzymatic mechanism of a multifunctional family 5 endoglucanase from Bacillus subtilis BS-5 with potential applications in the saccharification of cellulosic substrates

(2018) Bin Wu et al.   Biotechnology for Biofuels

Enhancement of catalytic activity and thermostability of a thermostable cellobiohydrolase from Chaetomium thermophilum by site-directed mutagenesis

(2018) Chao Han et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Engineering enhanced cellobiohydrolase activity

(2018) Larry E. Taylor et al.   Nature Communications

Rational engineering of Cel5E from Clostridium thermocellum to improve its thermal stability and catalytic activity

(2018) Ibrahim Torktaz et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Disulfide bonds elimination of endoglucanase II from Trichoderma reesei by site-directed mutagenesis to improve enzyme activity and thermal stability: An experimental and theoretical approach

(2018) Ali Akbarzadeh et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Altering the linker in processive GH5 endoglucanase 1 modulates lignin binding and catalytic properties

(2018) Zhen Wang et al.   Biotechnology for Biofuels

Purification and characterisation of processive-type endoglucanase and β-glucosidase from Aspergillus ochraceus MTCC 1810 through saccharification of delignified coir pith to glucose

(2016) P. Asha et al.   BIORESOURCE TECHNOLOGY

Loop variants of the thermophileRasamsonia emersoniiCel7A with improved activity against cellulose

(2016) Trine Holst Sørensen et al.   BIOTECHNOLOGY AND BIOENGINEERING

Single-molecule Imaging Analysis of Binding, Processive Movement, and Dissociation of CellobiohydrolaseTrichoderma reeseiCel6A and Its Domains on Crystalline Cellulose

(2016) Akihiko Nakamura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inter-domain Synergism Is Required for Efficient Feeding of Cellulose Chain into Active Site of Cellobiohydrolase Cel7A

(2016) Riin Kont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of a multi-function processive endoglucanase CHU_2103 from Cytophaga hutchinsonii

(2014) Cong Zhang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Cel48A fromThermobifida fusca: Structure and site directed mutagenesis of key residues

(2013) Maxim Kostylev et al.   BIOTECHNOLOGY AND BIOENGINEERING

Glycoside Hydrolase Processivity Is Directly Related to Oligosaccharide Binding Free Energy

(2013) Christina M. Payne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Processivity and Enzymatic Mode of a Glycoside Hydrolase Family 5 Endoglucanase from Volvariella volvacea

(2012) Fei Zheng et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Processive and nonprocessive cellulases for biofuel production—lessons from bacterial genomes and structural analysis

(2011) David B. Wilson   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dissecting structure–function–stability relationships of a thermostable GH5-CBM3 cellulase fromBacillus subtilis168

(2011) Camila R. Santos et al.   BIOCHEMICAL JOURNAL

Glycoside hydrolase family 9 processive endoglucanase from Clostridium phytofermentans: Heterologous expression, characterization, and synergy with family 48 cellobiohydrolase

(2010) Xiao-Zhou Zhang et al.   BIORESOURCE TECHNOLOGY

Cellulase activities in biomass conversion: measurement methods and comparison

(2010) Mehdi Dashtban et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Glycosidic-Bond Hydrolysis Mechanism Catalyzed by Cellulase Cel7A from Trichoderma reesei: A Comprehensive Theoretical Study by Performing MD, QM, and QM/MM Calculations

(2010) Jinghua Li et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Processive Endoglucanases Mediate Degradation of Cellulose by Saccharophagus degradans

(2009) B. J. Watson et al.   JOURNAL OF BACTERIOLOGY