miR-129-5p alleviates LPS-induced acute kidney injury via targeting HMGB1/TLRs/NF-kappaB pathway

MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1//TLR4/NF-κB pathway

(2020) Guang Wan et al.   BIOSCIENCE REPORTS

LncRNA NEAT1 affects inflammatory response by targeting miR-129-5p and regulating Notch signaling pathway in epilepsy

(2020) Yi Wan et al.   CELL CYCLE

β2-microglobulin is an independent indicator of acute kidney injury and outcomes in patients with intracerebral hemorrhage

(2020) Rui Wang et al.   MEDICINE

Psoriasis-Like Inflammation Induced Renal Dysfunction through the TLR/NF-κB Signal Pathway

(2020) Fang Ren et al.   Biomed Research International

Overexpression of miR-129-5p Mitigates Sepsis-Induced Acute Lung Injury by Targeting High Mobility Group Box 1

(2020) Peng Yang et al.   JOURNAL OF SURGICAL RESEARCH

Inhibition of HMGB1 attenuates podocyte apoptosis and epithelial-to-mesenchymal transition (EMT) by regulating autophagy flux

(2019) Juan Jin et al.   Journal of Diabetes

Honokiol alleviates sepsis-induced acute kidney injury in mice by targeting the miR-218-5p/heme oxygenase-1 signaling pathway

(2019) Tao Zhang et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

miR-129-5p Alleviates Neuropathic Pain Through Regulating HMGB1 Expression in CCI Rat Models

(2019) Jun Tian et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Upregulation of Mitochondrial Transcription Factor A Promotes the Repairment of Renal Tubular Epithelial Cells in Sepsis by Inhibiting Reactive Oxygen Species-Mediated Toll-Like Receptor 4/p38MAPK Signaling

(2019) Xin-Gui Dai et al.   PATHOBIOLOGY

miR-129-5p improves cardiac function in rats with chronic heart failure through targeting HMGB1

(2019) Na Xiao et al.   MAMMALIAN GENOME

Long non-coding RNA NEAT1 plays an important role in sepsis-induced acute kidney injury by targeting miR-204 and modulating the NF-κB pathway

(2018) Yi Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

LncRNA MALAT1 induces colon cancer development by regulating miR-129-5p/HMGB1 axis

(2018) Qiong Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

MiR-146b protect against sepsis induced mice myocardial injury through inhibition of Notch1

(2018) Xinhua Wang et al.   JOURNAL OF MOLECULAR HISTOLOGY

The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

(2018) Lu Meng et al.   MOLECULAR IMMUNOLOGY

Blockade of HMGB1 Attenuates Diabetic Nephropathy in Mice

(2018) Xiaochen Chen et al.   Scientific Reports

Value of urinary KIM-1 and NGAL combined with serum Cys C for predicting acute kidney injury secondary to decompensated cirrhosis

(2018) Lei Lei et al.   Scientific Reports

The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

(2018) Meihong Deng et al.   IMMUNITY

MiR-590-3p Attenuates Acute Kidney Injury by Inhibiting Tumor Necrosis Factor Receptor-Associated Factor 6 in Septic Mice

(2018) Jing Ma et al.   INFLAMMATION

MiR-155 Alleviates Septic Lung Injury by Inducing Autophagy Via Inhibition of Transforming Growth Factor-β-Activated Binding Protein 2

(2017) Fen Liu et al.   SHOCK

Sepsis-induced acute kidney injury

(2016) Hernando Gómez et al.   Current Opinion in Critical Care

MicroRNA-125b Prevents Cardiac Dysfunction in Polymicrobial Sepsis by Targeting TRAF6-Mediated Nuclear Factor κB Activation and p53-Mediated Apoptotic Signaling

(2016) He Ma et al.   JOURNAL OF INFECTIOUS DISEASES

Autophagy in acute kidney injury

(2016) Gur P. Kaushal et al.   KIDNEY INTERNATIONAL

Exogenous Carbon Monoxide Decreases Sepsis-Induced Acute Kidney Injury and Inhibits NLRP3 Inflammasome Activation in Rats

(2015) Peng Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MD-2 is required for disulfide HMGB1–dependent TLR4 signaling

(2015) Huan Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-129-5p modulates epithelial-to-mesenchymal transition by targeting SIP1 and SOX4 during peritoneal dialysis

(2015) Li Xiao et al.   LABORATORY INVESTIGATION

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(2015) Huan Yang et al.   MOLECULAR MEDICINE

miR-27a is up regulated and promotes inflammatory response in sepsis

(2014) Zhongchuan Wang et al.   CELLULAR IMMUNOLOGY

The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

(2013) Huan Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human macrophage and dendritic cell-specific silencing of high-mobility group protein B1 ameliorates sepsis in a humanized mouse model

(2012) C. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Renal Cell Apoptosis and New Treatment Options in Sepsis-Induced Acute Kidney Injury

(2012) Ayşe Koçkara et al.   RENAL FAILURE

LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile

(2012) Tarak Srivastava et al.   Journal of Cell Communication and Signaling

Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1

(2011) Asada Leelahavanichkul et al.   KIDNEY INTERNATIONAL

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

(2009) Ping Gao et al.   NATURE