Competition for Active TGFβ Cytokine Allows for Selective Retention of Antigen-Specific Tissue- Resident Memory T Cells in the Epidermal Niche

Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity

(2020) Chang Liu et al.   NATURE IMMUNOLOGY

Inhibitory checkpoint receptors control CD8+ resident memory T cells to prevent skin allergy

(2019) Pia Gamradt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Lymph node conduits transport virions for rapid T cell activation

(2019) Glennys V. Reynoso et al.   NATURE IMMUNOLOGY

Tissue-Resident T Cells and Other Resident Leukocytes

(2019) David Masopust et al.   Annual Review of Immunology

Keratinocyte-Mediated Activation of the Cytokine TGF-β Maintains Skin Recirculating Memory CD8+ T Cells

(2019) Toshiro Hirai et al.   IMMUNITY

Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis

(2019) Yi Yang et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Migratory DCs activate TGF-β to precondition naïve CD8+ T cells for tissue-resident memory fate

(2019) Vinidhra Mani et al.   SCIENCE

Migration and Function of Memory CD8+ T Cells in Skin

(2019) Toshiro Hirai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Charting the cis-regulome of activated B cells by coupling structural and functional genomics

(2019) Virendra K. Chaudhri et al.   NATURE IMMUNOLOGY

Targeted Expansion of Tissue-Resident CD8+ T Cells to Boost Cellular Immunity in the Skin

(2019) Samuel J. Hobbs et al.   Cell Reports

A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System

(2018) Yan Qin et al.   CELL

Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma

(2018) Sean R. McMaster et al.   Mucosal Immunology

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

(2018) Simone L. Park et al.   NATURE IMMUNOLOGY

Antibody blockade of IL-15 signaling has the potential to durably reverse vitiligo

(2018) Jillian M. Richmond et al.   Science Translational Medicine

Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

(2017) Youdong Pan et al.   NATURE

Local antigen in nonlymphoid tissue promotes resident memory CD8+T cell formation during viral infection

(2016) Tahsin N. Khan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen-dependent competition shapes the local repertoire of tissue-resident memory CD8 + T cells

(2016) Andreas Muschaweckh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

(2016) Javed Mohammed et al.   NATURE IMMUNOLOGY

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation

(2016) Nicholas Collins et al.   Nature Communications

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate

(2015) Laura K. Mackay et al.   IMMUNITY

Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection

(2015) L M Wakim et al.   Mucosal Immunology

Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma

(2015) Takeya Adachi et al.   NATURE MEDICINE

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Persistence of skin-resident memory T cells within an epidermal niche

(2014) A. Zaid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues

(2012) K. A. Casey et al.   JOURNAL OF IMMUNOLOGY

Skin infection generates non-migratory memory CD8+ TRM cells providing global skin immunity

(2012) Xiaodong Jiang et al.   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Autocrine/paracrine TGF- 1 inhibits Langerhans cell migration

(2012) A. Bobr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation

(2012) L. K. Mackay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental and Antigen Receptor-Derived Signals Support Sustained Surveillance of the Lungs by Pathogen-Specific Cytotoxic T Lymphocytes

(2011) Y.-T. Lee et al.   JOURNAL OF VIROLOGY

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

A rapid strategy to detect the recombined allele in LSL-TβRICA transgenic mice

(2010) David F. Vincent et al.   GENESIS

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

(2010) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

TGFβ: a sleeping giant awoken by integrins

(2010) John J. Worthington et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mice that lack activity of  v 6- and  v 8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

(2009) P. Aluwihare et al.   JOURNAL OF CELL SCIENCE

CD8 T Cells Producing IL-17 and IFN-γ Initiate the Innate Immune Response Required for Responses to Antigen Skin Challenge

(2009) Danielle D. Kish et al.   JOURNAL OF IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

GARP (LRRC32) is essential for the surface expression of latent TGF-  on platelets and activated FOXP3+ regulatory T cells

(2009) D. Q. Tran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of mice with conditionally activated transforming growth factor beta signaling through the TβRI/ALK5 receptor

(2008) Laurent Bartholin et al.   GENESIS

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE