Lymph node conduits transport virions for rapid T cell activation

First-in-Human Randomized, Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector

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The emergence of Zika virus and its new clinical syndromes

(2018) Theodore C. Pierson et al.   NATURE

The conduit system exports locally secreted IgM from lymph nodes

(2018) Guilhem R. Thierry et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD8 + T Cells Orchestrate pDC-XCR1 + Dendritic Cell Spatial and Functional Cooperativity to Optimize Priming

(2017) Anna Brewitz et al.   IMMUNITY

Dendritic cell and antigen dispersal landscapes regulate T cell immunity

(2017) Michael Y. Gerner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MVA vaccine encoding CMV antigens safely induces durable expansion of CMV-specific T cells in healthy adults

(2016) Corinna La Rosa et al.   BLOOD

The 3.8 A resolution cryo-EM structure of Zika virus

(2016) D. Sirohi et al.   SCIENCE

CXCR3 Chemokine Receptor Enables Local CD8+ T Cell Migration for the Destruction of Virus-Infected Cells

(2015) Heather D. Hickman et al.   IMMUNITY

Strategically Localized Dendritic Cells Promote Rapid T Cell Responses to Lymph-Borne Particulate Antigens

(2015) Michael Y. Gerner et al.   IMMUNITY

The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes

(2015) Pia Rantakari et al.   NATURE IMMUNOLOGY

In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity

(2015) Pervinder Sagoo et al.   NATURE MEDICINE

Inflammation-induced disruption of SCS macrophages impairs B cell responses to secondary infection

(2015) M. Gaya et al.   SCIENCE

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine

(2014) Matthew C. Woodruff et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

(2014) Sophie E. Acton et al.   NATURE

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

(2014) Viviana Cremasco et al.   NATURE IMMUNOLOGY

Fibroblastic reticular cells of the lymph node are required for retention of resting but not activated CD8+ T cells

(2014) A. E. Denton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anatomically Restricted Synergistic Antiviral Activities of Innate and Adaptive Immune Cells in the Skin

(2013) Heather D. Hickman et al.   Cell Host & Microbe

Peripheral Prepositioning and Local CXCL9 Chemokine-Mediated Guidance Orchestrate Rapid Memory CD8+ T Cell Responses in the Lymph Node

(2013) Wolfgang Kastenmüller et al.   IMMUNITY

Pathobiology of HIV/SIV-associated changes in secondary lymphoid tissues

(2013) Jacob D. Estes   IMMUNOLOGICAL REVIEWS

Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes

(2013) C.-Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokine Guidance of Central Memory T Cells Is Critical for Antiviral Recall Responses in Lymph Nodes

(2012) Jung Hwan Sung et al.   CELL

A Spatially-Organized Multicellular Innate Immune Response in Lymph Nodes Limits Systemic Pathogen Spread

(2012) Wolfgang Kastenmüller et al.   CELL

The Diaphragms of Fenestrated Endothelia: Gatekeepers of Vascular Permeability and Blood Composition

(2012) Radu V. Stan et al.   DEVELOPMENTAL CELL

Histo-Cytometry: A Method for Highly Multiplex Quantitative Tissue Imaging Analysis Applied to Dendritic Cell Subset Microanatomy in Lymph Nodes

(2012) Michael Y. Gerner et al.   IMMUNITY

Immortalized clones of fibroblastic reticular cells activate virus-specific T cells during virus infection

(2012) C. T. Ng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathology of Experimental Aerosol Zaire Ebolavirus Infection in Rhesus Macaques

(2012) N. A. Twenhafel et al.   VETERINARY PATHOLOGY

Chemokines control naive CD8+T cell selection of optimal lymph node antigen presenting cells

(2011) Heather D. Hickman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus

(2010) Matteo Iannacone et al.   NATURE

B-cell follicle development remodels the conduit system and allows soluble antigen delivery to follicular dendritic cells

(2009) M. Bajenoff et al.   BLOOD

Fibroblastic reticular cells and their role in viral hemorrhagic fevers

(2009) Keith E Steele et al.   Expert Review of Anti-Infective Therapy

Fibroblastic reticular cell infection by hemorrhagic fever viruses

(2009) Keith E Steele et al.   Immunotherapy

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone

(2008) Elke Scandella et al.   NATURE IMMUNOLOGY

Direct priming of antiviral CD8+ T cells in the peripheral interfollicular region of lymph nodes

(2008) Heather D Hickman et al.   NATURE IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE