Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction

Tissue-specific up-regulation of arginase I and II induced by p38 MAPK mediates endothelial dysfunction in type 1 diabetes mellitus

(2015) J Pernow et al.   BRITISH JOURNAL OF PHARMACOLOGY

Arginase: an old enzyme with new tricks

(2015) Ruth B. Caldwell et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Selective endothelin ETA and dual ETA/ETB receptor blockade improve endothelium-dependent vasodilatation in patients with type 2 diabetes and coronary artery disease

(2014) Arnar Rafnsson et al.   LIFE SCIENCES

Effect of Arginase Inhibition on Ischemia-Reperfusion Injury in Patients with Coronary Artery Disease with and without Diabetes Mellitus

(2014) Oskar Kövamees et al.   PLoS One

Arginase as a potential target in the treatment of cardiovascular disease: reversal of arginine steal?

(2013) John Pernow et al.   CARDIOVASCULAR RESEARCH

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

(2013) Francesco Paneni et al.   EUROPEAN HEART JOURNAL

Prevention of diabetes-induced arginase activation and vascular dysfunction by Rho kinase (ROCK) knockout

(2012) Lin Yao et al.   CARDIOVASCULAR RESEARCH

Arginase Inhibition Improves Endothelial Function in Patients With Coronary Artery Disease and Type 2 Diabetes Mellitus

(2012) Alexey Shemyakin et al.   CIRCULATION

Arginine bioavailability ratios are associated with cardiovascular mortality in patients referred to coronary angiography

(2011) Harald Sourij et al.   ATHEROSCLEROSIS

Diminished Global Arginine Bioavailability and Increased Arginine Catabolism as Metabolic Profile of Increased Cardiovascular Risk

(2009) W.H. Wilson Tang et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Endothelial Arginase II

(2008) Sungwoo Ryoo et al.   CIRCULATION RESEARCH

Diabetes-induced Coronary Vascular Dysfunction Involves Increased Arginase Activity

(2007) Maritza J. Romero et al.   CIRCULATION RESEARCH