Role of endoplasmic reticulum stress signalling in diabetic endothelial dysfunction and atherosclerosis

ER stress: Autophagy induction, inhibition and selection

(2015) Harun-Or Rashid et al.   Autophagy

Endoplasmic Reticulum Stress Aggravates Viral Myocarditis by Raising Inflammation Through the IRE1-Associated NF-κB Pathway

(2015) Xi Zha et al.   CANADIAN JOURNAL OF CARDIOLOGY

Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

(2015) Dipak P. Ramji et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Interleukin-1α deficiency attenuates endoplasmic reticulum stress-induced liver damage and CHOP expression in mice

(2015) Michal Kandel-Kfir et al.   JOURNAL OF HEPATOLOGY

CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis

(2015) Jeffrey A. Willy et al.   MOLECULAR BIOLOGY OF THE CELL

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

(2015) Daniela Senft et al.   TRENDS IN BIOCHEMICAL SCIENCES

Cellular Mechanisms of Endoplasmic Reticulum Stress Signaling in Health and Disease. 2. Protein misfolding and ER stress

(2014) Joseph E. Chambers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity

(2014) Madeleen Bosma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

(2014) Maria Galán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

TNF- -mediated caspase-8 activation induces ROS production and TRPM2 activation in adult ventricular myocytes

(2014) S. Roberge et al.   CARDIOVASCULAR RESEARCH

Hyperhomocysteinemia and Hyperglycemia Induce and Potentiate Endothelial Dysfunction via μ-Calpain Activation

(2014) Zhongjian Cheng et al.   DIABETES

Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1  in Response to TLR4 Stimulation through a Caspase-8- and TRIF-Dependent Pathway

(2014) K. Shenderov et al.   JOURNAL OF IMMUNOLOGY

JNK interaction with Sab mediates ER stress induced inhibition of mitochondrial respiration and cell death

(2014) S Win et al.   Cell Death & Disease

Role of Endoplasmic Reticulum Stress in Atherosclerosis and Diabetic Macrovascular Complications

(2014) Dmitry A. Chistiakov et al.   Biomed Research International

Endothelium and Its Alterations in Cardiovascular Diseases: Life Style Intervention

(2014) Gaia Favero et al.   Biomed Research International

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload

(2014) Robert A. Egnatchik et al.   Molecular Metabolism

Aberrant Endoplasmic Reticulum Stress in Vascular Smooth Muscle Increases Vascular Contractility and Blood Pressure in Mice Deficient of AMP-Activated Protein Kinase-α2 In Vivo

(2013) Bin Liang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells

(2013) Christos Adamopoulos et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue

(2013) G. Boden et al.   DIABETES

Involvement of advanced glycation end product-induced asymmetric dimethylarginine generation in endothelial dysfunction

(2013) Ryotaro Ando et al.   Diabetes & Vascular Disease Research

Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism

(2013) L. Salvadó et al.   DIABETOLOGIA

Targeting endoplasmic reticulum stress in metabolic disease

(2013) Stewart Siyan Cao et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation

(2013) W. Zhang et al.   GENES & DEVELOPMENT

Mitochondrial dysfunction and the inflammatory response

(2013) María J. López-Armada et al.   MITOCHONDRION

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Mechanisms of Diabetic Complications

(2013) Josephine M. Forbes et al.   PHYSIOLOGICAL REVIEWS

Free Fatty Acid Induces Endoplasmic Reticulum Stress and Apoptosis of β-cells by Ca2+/Calpain-2 Pathways

(2013) Wei Cui et al.   PLoS One

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

(2013) R. Volmer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of insulin resistance in endothelial dysfunction

(2013) Ranganath Muniyappa et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Endoplasmic Reticulum Stress Is Involved in Cardiac Damage and Vascular Endothelial Dysfunction in Hypertensive Mice

(2012) Modar Kassan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adverse Alterations in Mitochondrial Function Contribute to Type 2 Diabetes Mellitus–Related Endothelial Dysfunction in Humans

(2012) Tinoy J. Kizhakekuttu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial dysfunction : the early predictor of atherosclerosis

(2012) Mashudu Mudau et al.   Cardiovascular Journal of Africa

Hyperuricemia induces endothelial dysfunction via mitochondrial Na+/Ca2+ exchanger-mediated mitochondrial calcium overload

(2012) Quan Hong et al.   CELL CALCIUM

Inflammation, Endoplasmic Reticulum Stress, Autophagy, and the Monocyte Chemoattractant Protein-1/CCR2 Pathway

(2012) Pappachan E. Kolattukudy et al.   CIRCULATION RESEARCH

BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER

(2012) Nico Schäuble et al.   EMBO JOURNAL

The Delicate Balance Between Secreted Protein Folding and Endoplasmic Reticulum-Associated Degradation in Human Physiology

(2012) Christopher J. Guerriero et al.   PHYSIOLOGICAL REVIEWS

Molecular mechanisms and the role of saturated fatty acids in the progression of non-alcoholic fatty liver disease

(2012) Alexandra K. Leamy et al.   PROGRESS IN LIPID RESEARCH

ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

(2012) P Menu et al.   Cell Death & Disease

Mechanisms of ER Stress-Induced Apoptosis in Atherosclerosis

(2011) Christopher M. Scull et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Recent Advances on the Role of Cytokines in Atherosclerosis

(2011) Hafid Ait-Oufella et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Altered Mitochondrial Dynamics Contributes to Endothelial Dysfunction in Diabetes Mellitus

(2011) Sherene M. Shenouda et al.   CIRCULATION

Endoplasmic reticulum: ER stress regulates mitochondrial bioenergetics

(2011) Roberto Bravo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

(2011) R. Bravo et al.   JOURNAL OF CELL SCIENCE

ER Stress Inhibits mTORC2 and Akt Signaling Through GSK-3 -Mediated Phosphorylation of Rictor

(2011) C.-H. Chen et al.   Science Signaling

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

TNF-α-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-XL

(2010) J J Kim et al.   CELL DEATH AND DIFFERENTIATION

Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo

(2010) Yunzhou Dong et al.   CIRCULATION

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

The Role of Endoplasmic Reticulum Stress in the Progression of Atherosclerosis

(2010) Ira Tabas   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo

(2010) Y. Dong et al.   DIABETES

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

(2010) M. R. Dasu et al.   DIABETES CARE

Free fatty acids induce endothelial dysfunction and activate protein kinase C and nuclear factor-κB pathway in rat aorta

(2010) Hua Li et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

HLA-B35 Upregulates Endothelin-1 and Downregulates Endothelial Nitric Oxide Synthase via Endoplasmic Reticulum Stress Response in Endothelial Cells

(2010) S. Lenna et al.   JOURNAL OF IMMUNOLOGY

Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes

(2010) Chun-Lin Gao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Endoplasmic reticulum stress and atherosclerosis

(2010) Gökhan S Hotamisligil   NATURE MEDICINE

Mechanism of ER Stress-Induced Brain Damage by IP3 Receptor

(2010) Takayasu Higo et al.   NEURON

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Reduced Apoptosis and Plaque Necrosis in Advanced Atherosclerotic Lesions of Apoe−/− and Ldlr−/− Mice Lacking CHOP

(2009) Edward Thorp et al.   Cell Metabolism

Molecular Insights and Therapeutic Targets for Diabetic Endothelial Dysfunction

(2009) Jian Xu et al.   CIRCULATION

Chronic Endoplasmic Reticulum Stress Activates Unfolded Protein Response in Arterial Endothelium in Regions of Susceptibility to Atherosclerosis

(2009) Mete Civelek et al.   CIRCULATION RESEARCH

Endothelial Dysfunction as a Target for Prevention of Cardiovascular Disease

(2009) D. Versari et al.   DIABETES CARE

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

(2009) Ebru Erbay et al.   NATURE MEDICINE

The role of inflammatory cytokines in endothelial dysfunction

(2008) Cuihua Zhang   BASIC RESEARCH IN CARDIOLOGY

Cytokines and atherosclerosis: a comprehensive review of studies in mice

(2008) R. Kleemann et al.   CARDIOVASCULAR RESEARCH

Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition

(2008) H. Y. Fu et al.   CARDIOVASCULAR RESEARCH

Endothelial Dysfunction in Patients with Chronic Kidney Disease Results from Advanced Glycation End Products (AGE)-Mediated Inhibition of Endothelial Nitric Oxide Synthase through RAGE Activation

(2008) E. Linden et al.   Clinical Journal of the American Society of Nephrology

Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and  -Cell Death

(2008) D. S. Luciani et al.   DIABETES

Cytokine-Induced  -Cell Death Is Independent of Endoplasmic Reticulum Stress Signaling

(2008) M. C. Akerfeldt et al.   DIABETES

Effect of Endothelium-Specific Insulin Resistance on Endothelial Function In Vivo

(2008) E. R. Duncan et al.   DIABETES

Activation of protease calpain by oxidized and glycated LDL increases the degradation of endothelial nitric oxide synthase

(2008) Yunzhou Dong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

From endoplasmic-reticulum stress to the inflammatory response

(2008) Kezhong Zhang et al.   NATURE

Cytochrome c: functions beyond respiration

(2008) Yong-Ling P. Ow et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY