Transglutaminase 2 Inhibitor LDN 27219 Age-Dependently Lowers Blood Pressure and Improves Endothelium-Dependent Vasodilation in Resistance Arteries

The vicious cycle between transglutaminase 2 and reactive oxygen species in hyperglycemic memory–induced endothelial dysfunction

(2019) Jee-Yeon Lee et al.   FASEB JOURNAL

Pharmacologic inhibition of the enzymatic effects of tissue transglutaminase reduces cardiac fibrosis and attenuates cardiomyocyte hypertrophy following pressure overload

(2018) Arti V. Shinde et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor

(2018) Zhuo Wang et al.   Cell Death & Disease

Tissue Transglutaminase Modulates Vascular Stiffness and Function Through Crosslinking‐Dependent and Crosslinking‐Independent Functions

(2017) Jochen Steppan et al.   Journal of the American Heart Association

Role of tissue transglutaminase in age-associated ventricular stiffness

(2016) Young Jun Oh et al.   AMINO ACIDS

Involvement of transglutaminase 2 and voltage-gated potassium channels in cystamine vasodilatation in rat mesenteric small arteries

(2016) Morten Engholm et al.   BRITISH JOURNAL OF PHARMACOLOGY

Simultaneous analysis of enzyme structure and activity by kinetic capillary electrophoresis–MS

(2016) Gleb G Mironov et al.   Nature Chemical Biology

Inhibitors of tissue transglutaminase

(2015) Jeffrey W. Keillor et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Transglutaminase Regulation of Cell Function

(2014) Richard L. Eckert et al.   PHYSIOLOGICAL REVIEWS

Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice

(2013) Sung Mee Jung et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Vena cava and aortic smooth muscle cells express transglutaminases 1 and 4 in addition to transglutaminase 2

(2012) Kyle B. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Nitric oxide regulates tissue transglutaminase localization and function in the vasculature

(2011) Simran K. Jandu et al.   AMINO ACIDS

Decreased S -Nitrosylation of Tissue Transglutaminase Contributes to Age-Related Increases in Vascular Stiffness

(2010) Lakshmi Santhanam et al.   CIRCULATION RESEARCH

Crystal structure of human transglutaminase 2 in complex with adenosine triphosphate

(2010) Byeong-Gu Han et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES