Simultaneous analysis of enzyme structure and activity by kinetic capillary electrophoresis–MS

The Design of Covalent Allosteric Drugs

(2015) Ruth Nussinov et al.   Annual Review of Pharmacology and Toxicology

Real-time NMR monitoring of biological activities in complex physiological environments

(2015) Matthew J Smith et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Accurate small and wide angle x-ray scattering profiles from atomic models of proteins and nucleic acids

(2014) Hung T. Nguyen et al.   JOURNAL OF CHEMICAL PHYSICS

Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR

(2014) Daniel A. Keedy et al.   STRUCTURE

Allostery in Disease and in Drug Discovery

(2013) Ruth Nussinov et al.   CELL

Bioanalysis for Biocatalysis: Multiplexed Capillary Electrophoresis–Mass Spectrometry Assay for Aminotransferase Substrate Discovery and Specificity Profiling

(2013) Gleb G. Mironov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Real-Time Monitoring of Protein Conformational Dynamics in Solution Using Kinetic Capillary Electrophoresis

(2012) Christopher M. Clouthier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Native ion mobility-mass spectrometry and related methods in structural biology

(2012) A. Konijnenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Conformation Types of Ubiquitin [M+8H]8+ Ions from Water:Methanol Solutions: Evidence for the N and A States in Aqueous Solution

(2012) Huilin Shi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Protein activity regulation by conformational entropy

(2012) Shiou-Ru Tzeng et al.   NATURE

Using FLIM-FRET to Measure Conformational Changes of Transglutaminase Type 2 in Live Cells

(2012) Nicholas S. Caron et al.   PLoS One

Proteasome allostery as a population shift between interchanging conformers

(2012) A. M. Ruschak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and kinetic characterisation of human tissue transglutaminase

(2012) Isabelle Roy et al.   PROTEIN EXPRESSION AND PURIFICATION

Accessing protein conformational ensembles using room-temperature X-ray crystallography

(2011) J. S. Fraser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase

(2010) Ewa Jurneczko et al.   ANALYST

Ion Mobility and Collision-Induced Dissociation Analysis of Carbonic Anhydrase 2

(2010) Yoshiaki Nabuchi et al.   ANALYTICAL CHEMISTRY

Allostery and population shift in drug discovery

(2010) Gozde Kar et al.   CURRENT OPINION IN PHARMACOLOGY

Large conformational changes in proteins: signaling and other functions

(2010) Barry J Grant et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Coupling of receptor conformation and ligand orientation determine graded activity

(2010) John B Bruning et al.   Nature Chemical Biology

Fluorometric assay for tissue transglutaminase-mediated transamidation activity

(2009) Claudio Gnaccarini et al.   BIOORGANIC & MEDICINAL CHEMISTRY

NMR spectroscopy brings invisible protein states into focus

(2009) Andrew J Baldwin et al.   Nature Chemical Biology

Probing Invisible, Low-Populated States of Protein Molecules by Relaxation Dispersion NMR Spectroscopy: An Application to Protein Folding

(2008) Dmitry M. Korzhnev et al.   ACCOUNTS OF CHEMICAL RESEARCH

The bioorganic chemistry of transglutaminase — from mechanism to inhibition and engineering

(2008) Jeffrey W Keillor et al.   CANADIAN JOURNAL OF CHEMISTRY

Allosteric regulation and catalysis emerge via a common route

(2008) Nina M Goodey et al.   Nature Chemical Biology