Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
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Title
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice
Authors
Keywords
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Journal
GENES & DEVELOPMENT
Volume 35, Issue 1-2, Pages 117-132
Publisher
Cold Spring Harbor Laboratory
Online
2021-01-05
DOI
10.1101/gad.341875.120
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Note: Only part of the references are listed.- Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
- (2020) Helge M. Magnussen et al. Nature Communications
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- (2019) Timothy J Humpton et al. Cancer Discovery
- Pancreas regeneration
- (2018) Qiao Zhou et al. NATURE
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- (2017) Koji Nomura et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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- (2017) Sydney M. Moyer et al. Journal of Molecular Cell Biology
- Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity
- (2017) Koji Nomura et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Exploiting the p53 Pathway for Therapy
- (2017) Chit Fang Cheok et al. Cold Spring Harbor Perspectives in Medicine
- The Roles of MDM2 and MDMX in Cancer
- (2016) Orit Karni-Schmidt et al. Annual Review of Pathology-Mechanisms of Disease
- Attenuating the p53 Pathway in Human Cancers: Many Means to the Same End
- (2016) Amanda R. Wasylishen et al. Cold Spring Harbor Perspectives in Medicine
- Tamoxifen induces the development of hernia in mice by activating MMP-2 and MMP-13 expression
- (2015) Xingzhe Ma et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Results of the Phase I Trial of RG7112, a Small-Molecule MDM2 Antagonist in Leukemia
- (2015) M. Andreeff et al. CLINICAL CANCER RESEARCH
- Inflammation in acute and chronic pancreatitis
- (2015) Aida Habtezion CURRENT OPINION IN GASTROENTEROLOGY
- p53- and p73-independent activation of TIGAR expression in vivo
- (2015) P Lee et al. Cell Death & Disease
- Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis
- (2015) Jing Xue et al. Nature Communications
- Regulation of p53 by Mdm2 E3 Ligase Function Is Dispensable in Embryogenesis and Development, but Essential in Response to DNA Damage
- (2014) Laura A. Tollini et al. CANCER CELL
- Tissue-specific and age-dependent effects of global Mdm2 loss
- (2014) Yun Zhang et al. JOURNAL OF PATHOLOGY
- The p53-Mdm2 feedback loop protects against DNA damage by inhibiting p53 activity but is dispensable for p53 stability, development, and longevity
- (2013) V. Pant et al. GENES & DEVELOPMENT
- Mdm2 and MdmX partner to regulate p53
- (2012) Xinjiang Wang et al. FEBS LETTERS
- Acute Gastrointestinal Syndrome in High-Dose Irradiated Mice
- (2012) Catherine Booth et al. HEALTH PHYSICS
- BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer
- (2012) Hao Dou et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Validation of MdmX as a therapeutic target for reactivating p53 in tumors
- (2011) D. Garcia et al. GENES & DEVELOPMENT
- Heterodimerization of Mdm2 and Mdm4 is critical for regulating p53 activity during embryogenesis but dispensable for p53 and Mdm2 stability
- (2011) V. Pant et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) L. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Turning the RING Domain Protein MdmX into an Active Ubiquitin-Protein Ligase
- (2010) Saravanakumar Iyappan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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