Endoplasmic reticulum stress and autophagy contributed to cadmium nephrotoxicity in HK-2 cells and Sprague-Dawley rats

Autophagy Function and Regulation in Kidney Disease

(2020) Gur P. Kaushal et al.   Biomolecules

Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway

(2019) Chao Niu et al.   Autophagy

Oral exposure to cadmium and mercury alone and in combination causes damage to the lung tissue of Sprague-Dawley rats

(2019) Sirasha Venketsamy Koopsamy Naidoo et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Sirtuin-1 ameliorates cadmium-induced endoplasmic reticulum stress and pyroptosis through XBP-1s deacetylation in human renal tubular epithelial cells

(2019) Xin Chou et al.   ARCHIVES OF TOXICOLOGY

The association between lead and cadmium co-exposure and renal dysfunction

(2019) Xiao Chen et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Rosmarinic Acid Attenuates Cadmium-Induced Nephrotoxicity via Inhibition of Oxidative Stress, Apoptosis, Inflammation and Fibrosis

(2019) Swarnalata Joardar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cadmium overload modulates piroxicam-regulated oxidative damage and apoptotic pathways

(2019) Ahmed Abdeen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Induction of endoplasmic reticulum stress might be responsible for defective autophagy in cadmium-induced prostate carcinogenesis

(2019) Venkatesh Kolluru et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of sub-chronic, low-dose cadmium exposure on kidney damage and potential mechanisms

(2019) Qiling Liu et al.   Annals of Translational Medicine

Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells

(2019) Lingmin Zhang et al.   TOXICOLOGY LETTERS

The FoxO–Autophagy Axis in Health and Disease

(2019) Zhiyong Cheng   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle

(2019) Andreas Buch Møller et al.   Frontiers in Physiology

Calcimimetic compound NPS R-467 protects against chronic cadmium-induced mouse kidney injury by restoring autophagy process

(2019) Jie Gu et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Epidemiological study of kidney health in an area with high levels of soil cadmium and selenium: Does selenium protect against cadmium-induced kidney injury?

(2019) Juan Chen et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Sesamin induces ER stress-mediated apoptosis and activates autophagy in cervical cancer cells

(2018) Haowen Dou et al.   LIFE SCIENCES

The critical role of autophagy in cadmium-induced immunosuppression regulated by endoplasmic reticulum stress-mediated calpain activation in RAW264.7 mouse monocytes

(2018) Keum-Young So et al.   TOXICOLOGY

ERK1/2 MAPK promotes autophagy to suppress ER stress-mediated apoptosis induced by cadmium in rat proximal tubular cells

(2018) Tongwang Luo et al.   TOXICOLOGY IN VITRO

eIF2α kinases PERK and GCN2 act on FOXO to potentiate FOXO activity

(2018) Shiqiu You et al.   GENES TO CELLS

Betulinic acid protects mice from cadmium chloride-induced toxicity by inhibiting cadmium-induced apoptosis in kidney and liver

(2018) Rong Fan et al.   TOXICOLOGY LETTERS

On the Oxidative Damage by Cadmium on Kidney Mitochondrial Functions

(2018) Natalia Pavon et al.   Biochemistry and Cell Biology

Cadmium-mediated miR-30a-GRP78 leads to JNK-dependent autophagy in chicken kidney

(2018) Qunxiang Shi et al.   CHEMOSPHERE

Prevalence of exposure of heavy metals and their impact on health consequences

(2017) Kanwal Rehman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cadmium Exposure Impairs Cognition and Olfactory Memory in Male C57BL/6 Mice

(2017) Hao Wang et al.   TOXICOLOGICAL SCIENCES

Toxicity of cadmium and its health risks from leafy vegetable consumption

(2017) Yingying Huang et al.   Food & Function

Activation of PERK branch of ER stress mediates homocysteine-induced BKCa channel dysfunction in coronary artery via FoxO3a-dependent regulation of atrogin-1

(2017) Wen-Tao Sun et al.   Oncotarget

Epigallocatechin-3-gallate attenuates cadmium-induced chronic renal injury and fibrosis

(2016) Jinglou Chen et al.   FOOD AND CHEMICAL TOXICOLOGY

Hypoxia suppresses myocardial survival pathway through HIF-1α-IGFBP-3-dependent signaling and enhances cardiomyocyte autophagic and apoptotic effects mainly via FoxO3a-induced BNIP3 expression

(2016) Chih-Chung Feng et al.   GROWTH FACTORS

Autophagy and Tubular Cell Death in the Kidney

(2016) Andrea Havasi et al.   SEMINARS IN NEPHROLOGY

Quercetin inhibited cadmium-induced autophagy in the mouse kidney via inhibition of oxidative stress

(2016) Yuan Yuan et al.   Journal of Toxicologic Pathology

Endoplasmic reticulum stress eIF2α–ATF4 pathway-mediated cyclooxygenase-2 induction regulates cadmium-induced autophagy in kidney

(2016) B Luo et al.   Cell Death & Disease

Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation

(2016) Madhulika Tripathi et al.   Cell Death & Disease

Involvement of Endoplasmic Reticulum Stress, Autophagy and Apoptosis in Advanced Glycation End Products-Induced Glomerular Mesangial Cell Injury

(2016) Chih-Kang Chiang et al.   Scientific Reports

The ER stress regulator Bip mediates cadmium-induced autophagy and neuronal senescence

(2016) Tao Wang et al.   Scientific Reports

ER stress: Autophagy induction, inhibition and selection

(2015) Harun-Or Rashid et al.   Autophagy

Autophagy contributes to gefitinib-induced glioma cell growth inhibition

(2014) Cheng-Yi Chang et al.   EXPERIMENTAL CELL RESEARCH

Autophagy and the kidney: health and disease

(2014) Y. Takabatake et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Ligustrazine attenuates elevated levels of indoxyl sulfate, kidney injury molecule-1 and clusterin in rats exposed to cadmium

(2013) Zhou Lan et al.   FOOD AND CHEMICAL TOXICOLOGY

ER stress potentiates insulin resistance through PERK-mediated FOXO phosphorylation

(2013) W. Zhang et al.   GENES & DEVELOPMENT

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome

(2013) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

FOXO3 induces FOXO1-dependent autophagy by activating the AKT1 signaling pathway

(2012) Jingyi Zhou et al.   Autophagy

ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP

(2012) Wing-Kee Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cadmium-Induced Autophagy in Rat Kidney: An Early Biomarker of Subtoxic Exposure

(2011) Abderrahman Chargui et al.   TOXICOLOGICAL SCIENCES

Low level exposure to cadmium increases the risk of chronic kidney disease: analysis of the NHANES 1999-2006

(2010) Pietro Manuel Ferraro et al.   BMC PUBLIC HEALTH