Cardiolipin deficiency in Barth syndrome is not associated with increased superoxide/H 2 O 2 production in heart and skeletal muscle mitochondria

A critical appraisal of the tafazzin knockdown mouse model of Barth syndrome: what have we learned about pathogenesis and potential treatments?

(2019) Mindong Ren et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The use of site-specific suppressors to measure the relative contributions of different mitochondrial sites to skeletal muscle superoxide and hydrogen peroxide production

(2019) Renata L.S. Goncalves et al.   Redox Biology

Loss of tafazzin results in decreased myoblast differentiation in C2C12 cells: A myoblast model of Barth syndrome and cardiolipin deficiency

(2018) Wenjia Lou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome

(2018) Jordan M. Johnson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity

(2018) Alexander Bartelt et al.   NATURE MEDICINE

Mitochondrial and cytosolic sources of hydrogen peroxide in resting C2C12 myoblasts

(2018) Hoi-Shan Wong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cardiac mitochondrial structure and function in tafazzin-knockdown mice

(2018) Junhwan Kim et al.   MITOCHONDRION

Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia

(2018) Arpita Chowdhury et al.   Cell Reports

Defective STIM-mediated store operated Ca2+ entry in hepatocytes leads to metabolic dysfunction in obesity

(2017) Ana Paula Arruda et al.   eLife

Acquired deficiency of tafazzin in the adult heart: Impact on mitochondrial function and response to cardiac injury

(2016) Karol Szczepanek et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Suppressors of Superoxide-H 2 O 2 Production at Site I Q of Mitochondrial Complex I Protect against Stem Cell Hyperplasia and Ischemia-Reperfusion Injury

(2016) Martin D. Brand et al.   Cell Metabolism

Impaired Cardiolipin Biosynthesis Prevents Hepatic Steatosis and Diet-Induced Obesity

(2016) Laura K. Cole et al.   DIABETES

Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays

(2016) Satomi Miwa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Production of superoxide/hydrogen peroxide by the mitochondrial 2-oxoadipate dehydrogenase complex

(2016) Renata L.S. Goncalves et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial generation of superoxide and hydrogen peroxide as the source of mitochondrial redox signaling

(2016) Martin D. Brand   FREE RADICAL BIOLOGY AND MEDICINE

Defining functional classes of Barth syndrome mutation in humans

(2016) Ya-Wen Lu et al.   HUMAN MOLECULAR GENETICS

Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

(2016) Aaron L. Sverdlov et al.   Journal of the American Heart Association

Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies

(2016) Ana Saric et al.   Frontiers in Genetics

Cardiac-specific succinate dehydrogenase deficiency in Barth syndrome

(2015) J. Dudek et al.   EMBO Molecular Medicine

Endurance training ameliorates complex 3 deficiency in a mouse model of Barth syndrome

(2015) Meghan S. Soustek et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Suppressors of superoxide production from mitochondrial complex III

(2015) Adam L Orr et al.   Nature Chemical Biology

Cardiac Metabolic Pathways Affected in the Mouse Model of Barth Syndrome

(2015) Yan Huang et al.   PLoS One

Production of superoxide/H2O2 by dihydroorotate dehydrogenase in rat skeletal muscle mitochondria

(2014) Martin Hey-Mogensen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sites of Superoxide and Hydrogen Peroxide Production by Muscle Mitochondria Assessedex Vivounder Conditions Mimicking Rest and Exercise

(2014) Renata L. S. Goncalves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The 2-Oxoacid Dehydrogenase Complexes in Mitochondria Can Produce Superoxide/Hydrogen Peroxide at Much Higher Rates Than Complex I

(2014) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies

(2014) Gang Wang et al.   NATURE MEDICINE

Mitochondria-Targeted Antioxidant Prevents Cardiac Dysfunction Induced by Tafazzin Gene Knockdown in Cardiac Myocytes

(2014) Quan He et al.   Oxidative Medicine and Cellular Longevity

Tafazzin knockdown interrupts cell cycle progression in cultured neonatal ventricular fibroblasts

(2013) Quan He et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Neutrophil-mediated oxidation of erythrocyte peroxiredoxin 2 as a potential marker of oxidative stress in inflammation

(2013) Simone B. Bayer et al.   FASEB JOURNAL

Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria

(2013) Irina V. Perevoshchikova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dysfunctional cardiac mitochondrial bioenergetic, lipidomic, and signaling in a murine model of Barth syndrome

(2013) Michael A. Kiebish et al.   JOURNAL OF LIPID RESEARCH

Lipids of mitochondria

(2013) Susanne E. Horvath et al.   PROGRESS IN LIPID RESEARCH

Unexpected effects of voluntary exercise training on natriuretic peptide and receptor mRNA expression in the ob/ob mouse heart

(2013) Tom L. Broderick et al.   REGULATORY PEPTIDES

Cardiolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome

(2013) Jan Dudek et al.   Stem Cell Research

Diminished Exercise Capacity and Mitochondrial bc1 Complex Deficiency in Tafazzin-Knockdown Mice

(2013) Corey Powers et al.   Frontiers in Physiology

Sites of reactive oxygen species generation by mitochondria oxidizing different substrates

(2013) Casey L. Quinlan et al.   Redox Biology

Native rates of superoxide production from multiple sites in isolated mitochondria measured using endogenous reporters

(2012) Casey L. Quinlan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of Cardiolipin Leads to Perturbation of Mitochondrial and Cellular Iron Homeostasis

(2012) Vinay A. Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Refined Analysis of Superoxide Production by Mitochondrialsn-Glycerol 3-Phosphate Dehydrogenase

(2012) Adam L. Orr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle

(2011) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signal Transduction by Mitochondrial Oxidants

(2011) Toren Finkel   JOURNAL OF BIOLOGICAL CHEMISTRY

A guide to analysis of mouse energy metabolism

(2011) Matthias H Tschöp et al.   NATURE METHODS

Characterization of a Transgenic Short Hairpin RNA-Induced Murine Model of Tafazzin Deficiency

(2010) Meghan S. Soustek et al.   HUMAN GENE THERAPY

Cardiac and Skeletal Muscle Defects in a Mouse Model of Human Barth Syndrome

(2010) Devrim Acehan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Analysis of Cellular Glycerophospholipids Enabled by Multiplexed Solvent Dependent Analyte−Matrix Interactions

(2008) Gang Sun et al.   ANALYTICAL CHEMISTRY

Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

(2008) Steven M. Claypool et al.   JOURNAL OF CELL BIOLOGY

Loss of tafazzin in yeast leads to increased oxidative stress during respiratory growth

(2008) Shuliang Chen et al.   MOLECULAR MICROBIOLOGY