Multicomponent reactions (MCR) in medicinal chemistry: a patent review (2010-2020)

ClpP Protease, a Promising Antimicrobial Target

(2019) Carlos Moreno-Cinos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Groebke-Blackburn-Bienaymé Reaction

(2019) André Boltjes et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Photoinduced Multicomponent Reactions

(2016) Silvia Garbarino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent reactions: A simple and efficient route to heterocyclic phosphonates

(2016) Mohammad Haji   Beilstein Journal of Organic Chemistry

Synthesis of epimer of Taniaphos ligand

(2016) Ambroz Almássy et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Ugi and Passerini Reactions of Biocatalytically Derived Chiral Aldehydes: Application to the Synthesis of Bicyclic Pyrrolidines and of Antiviral Agent Telaprevir

(2015) Lisa Moni et al.   JOURNAL OF ORGANIC CHEMISTRY

Groebke–Blackburn–Bienaymé multicomponent reaction: emerging chemistry for drug discovery

(2015) Saad Shaaban et al.   MOLECULAR DIVERSITY

Multicomponent reactions: advanced tools for sustainable organic synthesis

(2014) Răzvan C. Cioc et al.   GREEN CHEMISTRY

What do we know about multicomponent reactions? Mechanisms and trends for the Biginelli, Hantzsch, Mannich, Passerini and Ugi MCRs

(2014) Haline G. O. Alvim et al.   RSC Advances

Modern multicomponent reactions for better drug syntheses

(2014) Tryfon Zarganes-Tzitzikas et al.   Organic Chemistry Frontiers

Supported protic acid-catalyzed synthesis of 2,3-disubstituted thiazolidin-4-ones: enhancement of the catalytic potential of protic acid by adsorption on solid supports

(2013) Dinesh Kumar et al.   GREEN CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Efficient Synthesis of Functionalized Dihydro-1H-indol-4(5H)-ones via One-Pot Three-Component Reaction under Catalyst-Free Conditions

(2013) Hui-Yan Wang et al.   ACS Combinatorial Science

Chemistry and Biology Of Multicomponent Reactions

(2012) Alexander Dömling et al.   CHEMICAL REVIEWS

Catalytic procedures for multicomponent synthesis of imidazoles: selectivity control during the competitive formation of tri- and tetrasubstituted imidazoles

(2012) Dinesh Kumar et al.   GREEN CHEMISTRY

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Application of Ionic Liquids: [bmim][MeSO4] as a Recyclable Organocatalyst in the Multicomponent Reaction for the Preparation of Dihydropyrimidinones and -thiones

(2011) Asit Chakraborti et al.   SYNTHESIS-STUTTGART

A highly efficient synthesis of telaprevir by strategic use of biocatalysis and multicomponent reactions

(2010) Anass Znabet et al.   CHEMICAL COMMUNICATIONS

Multicomponent reactions for the synthesis of pyrroles

(2010) Verónica Estévez et al.   CHEMICAL SOCIETY REVIEWS

Efficient Multicomponent Reaction Synthesis of the Schistosomiasis Drug Praziquantel

(2010) Haiping Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Highly Convergent Synthesis of Tricyclic N-Heterocycles Coupling an Ugi Reaction with a Tandem SN2′-Heck Double Cyclization

(2010) Renata Riva et al.   JOURNAL OF ORGANIC CHEMISTRY

One-Pot Synthesis of Photochromic 6′-Amino-Substituted Spirooxazines from 1-Nitroso-2-naphthol Zinc Chelate and Indoline Base

(2010) Mei-Li Pang et al.   SYNTHESIS-STUTTGART

Iodine catalyzed one-pot five-component reactions for direct synthesis of densely functionalized piperidines

(2010) Abu T. Khan et al.   TETRAHEDRON

Cyanoacetamide MCR (III): Three-Component Gewald Reactions Revisited

(2009) Kan Wang et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Synthesis of Prostaglandin and Phytoprostane B1Via Regioselective Intermolecular Pauson−Khand Reactions†

(2009) Ana Vázquez-Romero et al.   ORGANIC LETTERS

Multicomponent reactions in fungicide research: The discovery of mandipropamid

(2007) Clemens Lamberth et al.   BIOORGANIC & MEDICINAL CHEMISTRY