Size-shrinkable and protein kinase Cα-recognizable nanoparticles for deep tumor penetration and cellular internalization

Enhanced lysosome escape mediated by 1,2-dicarboxylic-cyclohexene anhydride-modified poly-L-lysine dendrimer as a gene delivery system

(2020) Jianmin Shen et al.   Asian Journal of Pharmaceutical Sciences

Polymeric Engineering of Nanoparticles for Highly Efficient Multifunctional Drug Delivery Systems

(2019) Beatrice Fortuni et al.   Scientific Reports

pH-responsive controlled release of mesoporous silica nanoparticles capped with Schiff base copolymer gatekeepers: Experiment and molecular dynamics simulation

(2019) Shiyuan Peng et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Targeted pharmacokinetics of polymeric micelles modified with glycyrrhetinic acid and hydrazone bond in H22 tumor-bearing mice

(2019) Yan Zheng et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Dendrigraft of Poly-l-lysine as a Promising Candidate To Reverse Heparin-based Anticoagulants in Clinical Settings

(2019) Benjamin Ourri et al.   ACS Medicinal Chemistry Letters

ROS-responsive nanoparticles based on amphiphilic hyperbranched polyphosphoester for drug delivery: Light-triggered size-reducing and enhanced tumor penetration

(2019) Hua Jin et al.   BIOMATERIALS

Modulating the site-specific oral delivery of sorafenib using sugar-grafted nanoparticles for hepatocellular carcinoma treatment

(2019) Lakshmi Tunki et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

PEGylated lipid bilayer coated mesoporous silica nanoparticles co-delivery of paclitaxel and curcumin leads to increased tumor site drug accumulation and reduced tumor burden

(2019) Jiafeng Gao et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Enzyme-triggered size shrink and laser-enhanced NO release nanoparticles for deep tumor penetration and combination therapy

(2018) Chuan Hu et al.   BIOMATERIALS

pH-Sensitive nanoparticles as smart carriers for selective intracellular drug delivery to tumor

(2018) Xin-Xin Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Size shrinkable drug delivery nanosystems and priming the tumor microenvironment for deep intratumoral penetration of nanoparticles

(2018) Yimin Niu et al.   JOURNAL OF CONTROLLED RELEASE

Theranostic size-reducible and no donor conjugated gold nanocluster fabricated hyaluronic acid nanoparticle with optimal size for combinational treatment of breast cancer and lung metastasis

(2018) Rui Liu et al.   JOURNAL OF CONTROLLED RELEASE

Stimuli-responsive gel-micelles with flexible modulationof drug release for maximized antitumor efficacy

(2018) Djamila Aouameur et al.   Nano Research

A size switchable nanoplatform for targeting the tumor microenvironment and deep tumor penetration

(2018) Xingli Cun et al.   Nanoscale

A size-shrinkable nanoparticle-based combined anti-tumor and anti-inflammatory strategy for enhanced cancer therapy

(2018) Zhengze Lu et al.   Nanoscale

Cellular uptake mechanism and clearance kinetics of fluorescence-labeled glycyrrhetinic acid and glycyrrhetinic acid–modified liposome in hepatocellular carcinoma cells

(2017) Yuqi Sun et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Glycyrrhetinic acid-functionalized mesoporous silica nanoparticles as hepatocellular carcinoma-targeted drug carrier

(2017) Yongjiu Lv et al.   International Journal of Nanomedicine

Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery

(2016) Kang Chen et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Tumor microenvironment and intracellular signal-activated nanomaterials for anticancer drug delivery

(2016) Ran Mo et al.   Materials Today

The Role of Micelle Size in Tumor Accumulation, Penetration, and Treatment

(2015) Jinqiang Wang et al.   ACS Nano

Integrin-mediated active tumor targeting and tumor microenvironment response dendrimer-gelatin nanoparticles for drug delivery and tumor treatment

(2015) Guanlian Hu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Doxorubicin-Loaded Glycyrrhetinic Acid Modified Recombinant Human Serum Albumin Nanoparticles for Targeting Liver Tumor Chemotherapy

(2015) Wen-Wen Qi et al.   MOLECULAR PHARMACEUTICS

Enzyme responsive mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo

(2015) Junjie Liu et al.   Nanoscale

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Integration of Nanoassembly Functions for an Effective Delivery Cascade for Cancer Drugs

(2014) Qihang Sun et al.   ADVANCED MATERIALS

Distribution and accumulation of Cy5.5-labeled thermally cross-linked superparamagnetic iron oxide nanoparticles in the tissues of ICR mice

(2014) Jin Joo Hue et al.   Journal of Veterinary Science

Surface Charge-Switchable Polymeric Magnetic Nanoparticles for the Controlled Release of Anticancer Drug

(2013) Jian-Min Shen et al.   ACS Applied Materials & Interfaces

Study and evaluation of mechanisms of dual targeting drug delivery system with tumor microenvironment assays compared with normal assays

(2013) Huile Gao et al.   Acta Biomaterialia

Doxorubicin delivery to 3D multicellular spheroids and tumors based on boronic acid-rich chitosan nanoparticles

(2013) Xin Wang et al.   BIOMATERIALS

Tumor targeting and microenvironment-responsive nanoparticles for gene delivery

(2013) Shixian Huang et al.   BIOMATERIALS

Strategies on the nuclear-targeted delivery of genes

(2013) Jing Yao et al.   JOURNAL OF DRUG TARGETING

cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy

(2013) Jian-Min Shen et al.   PHARMACOLOGICAL RESEARCH

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport

(2013) Alexandre Albanese et al.   Nature Communications

Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo

(2012) Keyang Huang et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Apoptosis in human hepatoma HepG2 cells induced by corn peptides and its anti-tumor efficacy in H22 tumor bearing mice

(2012) Jiang-Tao Li et al.   FOOD AND CHEMICAL TOXICOLOGY

Self-assembly and liver targeting of sulfated chitosan nanoparticles functionalized with glycyrrhetinic acid

(2011) Qin Tian et al.   Nanomedicine-Nanotechnology Biology and Medicine

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

(2011) H. Cabral et al.   Nature Nanotechnology

Polycationic Nanodrug Covered with Hyaluronic Acid for Treatment of P-Glycoprotein Overexpressing Cancer Cells

(2010) Hyeona Yim et al.   BIOMACROMOLECULES

Development of glycyrrhetinic acid-modified stealth cationic liposomes for gene delivery

(2010) Zhi Yao He et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Cancer stem cells in solid tumors

(2010) Patrick C. Hermann et al.   SEMINARS IN CANCER BIOLOGY

Target specific and long-acting delivery of protein, peptide, and nucleotide therapeutics using hyaluronic acid derivatives

(2009) Eun Ju Oh et al.   JOURNAL OF CONTROLLED RELEASE

Mediating Tumor Targeting Efficiency of Nanoparticles Through Design

(2009) Steven D. Perrault et al.   NANO LETTERS

Design considerations for tumour-targeted nanoparticles

(2009) Hak Soo Choi et al.   Nature Nanotechnology

3-D Tissue Culture Systems for the Evaluation and Optimization of Nanoparticle-Based Drug Carriers

(2008) Thomas Tyrel Goodman et al.   BIOCONJUGATE CHEMISTRY

Factors Affecting the Clearance and Biodistribution of Polymeric Nanoparticles

(2008) Frank Alexis et al.   MOLECULAR PHARMACEUTICS