Article
Chemistry, Multidisciplinary
Xue Wang, Shiyi Sun, Boxin Zhang, Jie Han
Summary: Current disinfection methods for shared public transportation in densely populated cities have limitations due to the risk of viral transmission, and there is a need for alternative strategies that are adapted to actual usage situations.
ENVIRONMENTAL CHEMISTRY LETTERS
(2021)
Article
Multidisciplinary Sciences
Salmaan Sharif, Aamer Ikram, Adnan Khurshid, Muhammad Salman, Nayab Mehmood, Yasir Arshad, Jamal Ahmed, Rana Muhammad Safdar, Lubna Rehman, Ghulam Mujtaba, Jaffar Hussain, Johar Ali, Mehar Angez, Muhammad Masroor Alam, Ribqa Akthar, Muhammad Wasif Malik, Mirza Zeeshan Iqbal Baig, Muhammad Suleman Rana, Muhammad Usman, Muhammad Qaisar Ali, Abdul Ahad, Nazish Badar, Massab Umair, Sana Tamim, Asiya Ashraf, Faheem Tahir, Nida Ali
Summary: The study found 27% of wastewater samples tested positive for SARs-CoV-2, indicating the potential for monitoring viral spread through wastewater surveillance. Additionally, the detection of virus sequence data in wastewater highlights the importance of surveillance for early warning signs.
Article
Biology
Leire Egia-Mendikute, Alexandre Bosch, Endika Prieto-Fernandez, So Young Lee, Borja Jimenez-Lasheras, Ana Garcia del Rio, Asier Antonana-Vildosola, Chiara Bruzzone, Maider Bizkarguenaga, Nieves Embade, Ruben Gil-Redondo, Maria Luz Martinez-Chantar, Marcos Lopez-Hoyos, Nicola G. A. Abrescia, Jose M. Mato, Oscar Millet, Asis Palazon
Summary: Egia-Mendikute et al. have developed a multiplexed flow cytometric bead array to detect antibodies reactive to three immunogenic SARS-CoV-2 proteins simultaneously. This assay is more sensitive than ELISA and has superior potential to detect low antibody titers, even in COVID-19-negative individuals.
COMMUNICATIONS BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Viviane Fongaro Botosso, Soraia Attie Calil Jorge, Renato Mancini Astray, Ana Marcia de Sa Guimaraes, Monica Beatriz Mathor, Patricia dos Santos de Carneiro, Edison Luiz Durigon, Dimas Covas, Danielle Bruna Leal de Oliveira, Ricardo das Neves Oliveira, Durvanei Augusto Maria, Silas Fernandes Eto, Neuza Maria Frazatti Gallina, Giselle Pidde, Carla Cristina Squaiella-Baptistao, Dilza Trevisan Silva, Isadora Maria Villas-Boas, Dayanne Carla Fernandes, Aline Vivian Vatti Auada, Alexandre Campos Banari, Antonio Francisco de Souza Filho, Camila Bianconi, Carla Lilian de Agostini Utescher, Denise Cristina Andre Oliveira, Douglas Oscar Ceolin Mariano, Flavia Ferreira Barbosa, Giuliana Rondon, Josana Kapronezai, Juliana Galvao da Silva, Mauricio Barbugiani Goldfeder, Priscila Comone, Regis Edgar Castilho Junior, Taiana Taina Silva Pereira, Fan Hui Wen, Denise Tambourgi, Ana Marisa Chudzinski-Tavassi
Summary: The new outbreak of COVID-19 has caused millions of deaths worldwide. Efforts are being made to find effective treatments, such as using immunoglobulin from immunized animals or plasma from convalescent patients. Clinical trials using anti-SARS-CoV-2 immunoglobulins from horses immunized with spike protein are underway. Researchers have developed an anti-SARS-CoV-2 equine F(ab ')(2) immunoglobulin that successfully neutralizes the virus, is safe in animal models, and reduces the severity of the disease in a hamster model of SARS-CoV-2 infection.
SCIENTIFIC REPORTS
(2022)
Review
Immunology
Anish Pillai, Anuja Nayak, Deepika Tiwari, Pratichi Kadam Pillai, Aakash Pandita, Sachin Sakharkar, Haribalakrishna Balasubramanian, Nandkishor Kabra
Summary: Since the COVID-19 pandemic began in early 2020, there has been increased understanding of its pathogenesis and improved surveillance and prevention measures. While the incidence of COVID-19 among children and neonates has risen, the proportion of severe disease in young children has not increased. Key protective mechanisms in young children include placental barrier, differential expression of ACE-2 receptors, immature immune response, and passive transfer of antibodies. Vaccinating young children presents a complex risk-benefit balance, considering their lower risk of severe illness and limited evidence on long-term vaccine safety. This review outlines current evidence, guidelines, controversies, knowledge gaps, and ethical issues related to COVID-19 vaccination in young children, emphasizing the need for individual and community considerations in regional immunization policies.
Article
Environmental Sciences
Manish Srivastava, Neha Srivastava, P. K. Mishra, Bansi D. Malhotra
Summary: This study provides an overview of the COVID-19 pandemic and nanomaterials-enabled biosensing approaches for the diagnosis of SARS-CoV-2. Despite limited research on nanomaterials-enabled biosensing techniques, the review summarizes nanomaterials-mediated improved biosensing strategies and possible mechanisms for diagnosing COVID-19.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Environmental Sciences
Oskar Wisniewski, Wieslaw Kozak, Maciej Wisniewski
Summary: COVID-19, caused by the novel viral agent SARS-CoV-2, has been declared a pandemic by the WHO, with over 70,000 cases and over 2000 deaths recorded in Poland as of September 10, 2020. Weather factors, including ground-level ozone concentration, have been found to inversely correlate with the daily number of COVID-19 cases in Warsaw, Poland.
AIR QUALITY ATMOSPHERE AND HEALTH
(2021)
Review
Biochemistry & Molecular Biology
Ridhima Kaul, Pradipta Paul, Sanjay Kumar, Dietrich Buesselberg, Vivek Dhar Dwivedi, Ali Chaari
Summary: This review summarizes the activities and structure-activity relationships of flavonoids in combating SARS-CoV-2 from in vitro studies to clinical research. The study found that flavonoids such as quercetin and myricetin derivatives, baicalein, baicalin, EGCG, and tannic acid show promising activities against SARS-CoV-2.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Mathematics, Applied
Songbai Guo, Yuling Xue, Rong Yuan, Maoxing Liu
Summary: Considering the transmission characteristics of COVID-19, this study develops a model that takes into account time delays and exposed infections. The global dynamics of the model are investigated, showing that the COVID-19-free equilibrium is globally asymptotically stable if the control reproduction number is 1, while it is unstable and the COVID-19 equilibrium is stable if the reproduction number is above 1. Numerical simulations reveal that strengthening quarantine measures helps control the epidemic in India. Additionally, the time delay affects the variables, with shorter delays leading to smaller final epidemic sizes.
Review
Medicine, General & Internal
Yasameen E. Muzahim, David C. Parish, Hemant Goyal
Summary: Acute pancreatitis associated with SARS-CoV-2 infection can cause symptoms such as abdominal pain, nausea, and vomiting, possibly related to the upregulation of cell receptors or inflammatory cytokines, but there is currently insufficient data to confirm the causality.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Immunology
Nandan Gautam, Shyam Madathil, Natascia Tahani, Shaun Bolton, Dhruv Parekh, James Stockley, Shraddha Goyal, Hannah Qureshi, Sadhika Yasmin, Brendan G. Cooper, Jennifer Short, Tarekegn Geberhiwot
Summary: A study found that a significant proportion of severely ill COVID-19 patients still experience symptoms such as breathlessness, fatigue, pain, reduced mobility, depression, and decreased quality of life 4-7 months after disease onset, with symptomatic patients having more residual chest radiographic and LFT abnormalities.
CLINICAL INFECTIOUS DISEASES
(2022)
Review
Pharmacology & Pharmacy
Majambu Mbikay, Michel Chretien
Summary: Isoquercetin and quercetin are secondary metabolites with antioxidant, anti-inflammatory, immune-regulatory, and anticoagulant activities. Isoquercetin is more easily absorbed in vivo, providing favorable pharmacokinetics compared to quercetin. They exhibit broad-spectrum antiviral activities and may be useful in preventing or treating Covid-19.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Medicine, Research & Experimental
William R. Morgenlander, Stephanie N. Henson, Daniel R. Monaco, Athena Chen, Kirsten Littlefield, Evan M. Bloch, Eric Fujimura, Ingo Ruczinski, Andrew R. Crowley, Harini Natarajan, Savannah E. Butler, Joshua A. Weiner, Mamie Z. Li, Tania S. Bonny, Sarah E. Benner, Ashwin Balagopal, David Sullivan, Shmuel Shoham, Thomas C. Quinn, Susan H. Eshleman, Arturo Casadevall, Andrew D. Redd, Oliver Laeyendecker, Margaret E. Ackerman, Andrew Pekosz, Stephen J. Elledge, Matthew Robinson, Aaron A. R. Tobian, H. Benjamin Larman
Summary: This study found strong correlation between the functionality of COVID-19 convalescent plasma and polyclonal antibody targeting of specific peptides in the SARS-CoV-2 spike protein. Antibody responses to specific coronaviruses correlated with the development of highly neutralizing antibodies against CoV-2. Plasma donations reactive to the CoV-2 spike receptor binding domain had higher neutralizing titers.
JOURNAL OF CLINICAL INVESTIGATION
(2021)
Review
Immunology
Yuxin Yan, Yoongxin Pang, Zhuoyi Lyu, Ruiqi Wang, Xinyun Wu, Chong You, Haitao Zhao, Sivakumar Manickam, Edward Lester, Tao Wu, Cheng Heng Pang
Summary: Developing COVID-19 vaccines is crucial for the world to return to pre-pandemic normalcy. Thirteen vaccines have been approved, with over 90 candidates in clinical trials. Despite being in its infancy, current progress in vaccine development is promising.
Article
Surgery
Martin D. Haug, Garyfalia Lekakis, Mario Bussi, Nazim Cerkes, Jay Calvert, Charles East, Olivier Gerbault, Wolfgang Gubisch, Werner Heppt, Haldun Kamburoglu, Sam Most, Carlo M. Oranges, Josef Vavrina, Rod J. Rohrich, Enrico Robotti
Summary: International leading experts in rhinosurgery conducted discussions and developed consensus recommendations on how to safely perform rhinoplasty, improving surgical safety and minimizing infection risks.
PLASTIC AND RECONSTRUCTIVE SURGERY
(2021)
Article
Chemistry, Multidisciplinary
Jose Luis Sanchez-Salvador, Ana Balea, Carlos Negro, Maria Concepcion Monte, Angeles Blanco
Summary: This study proposes a method based on gel point to calculate the dispersion degree and aspect ratio of cellulose micro and nanofibrils in water suspensions. The results show that higher stirring speeds decrease the dispersion capability and cause network collapse, while intermediate stirring speeds result in better dispersion behavior and network structure. Higher dispersion of cellulose before adding to the pulp leads to higher mechanical properties.
Article
Materials Science, Paper & Wood
Hongyu Xu, Jose Luis Sanchez-Salvador, Ana Balea, Angeles Blanco, Carlos Negro
Summary: This study optimized TEMPO-mediated oxidation reactions to reduce costs while achieving efficient and sustainable production of CNFs. Through adjusting reaction conditions, the carboxyl groups were increased while reducing catalyst doses, resulting in highly fibrillated CNFs with lower environmental impact.
Article
Environmental Sciences
Laura B. Torres-Mata, Omar Garcia-Perez, Francisco Rodriguez-Esparragon, Angeles Blanco, Jesus Villar, Fernando Ruiz-Apodaca, Jose L. Martin-Barrasa, Jesus M. Gonzalez-Martin, Pedro Serrano-Aguilar, Jose E. Pinero, Elizabeth Cordoba-Lanus, Jacob Lorenzo-Morales, Bernardino Clavo
Summary: This study assessed the optimal conditions of ozone treatment for eliminating heat-inactivated SARS-CoV-2 from office supplies and clinical equipment. Results showed that ozone could effectively eliminate the virus RNA, providing an additional tool to control the spread of the COVID-19 pandemic.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Polymer Science
Francisco de Borja Ojembarrena, Jose Luis Sanchez-Salvador, Sergio Mateo, Ana Balea, Angeles Blanco, Noemi Merayo, Carlos Negro
Summary: Cellulose nanofibers (CNF) are sustainable nanomaterials that can be used as adsorbents for hexavalent chromium removal. Hydrophobization of CNF improves their adsorption capacity. The optimal conditions for hexavalent chromium removal are pH 3 and an adsorbent dosage above 500 mg/L.
Article
Environmental Sciences
Bernardino Clavo, Angeles Canovas-Molina, Yolanda Ramallo-Farina, Mario Federico, Delvys Rodriguez-Abreu, Saray Galvan, Ivone Ribeiro, Susana C. Marques da Silva, Minerva Navarro, Damian Gonzalez-Beltran, Juan A. Diaz-Garrido, Sara Cazorla-Rivero, Francisco Rodriguez-Esparragon, Pedro Serrano-Aguilar
Summary: The aim of this study was to evaluate the effect of ozone treatment on the health-related quality of life (HRQOL) and grade of toxicity in cancer survivors with chronic side effects. The results showed that ozone treatment significantly improved HRQOL and decreased toxicity grade. These findings highlight the potential benefits of ozone treatment in cancer survivors.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2023)
Article
Chemistry, Multidisciplinary
Francisco de Borja Ojembarrena, Hassan Sammaraie, Cristina Campano, Angeles Blanco, Noemi Merayo, Carlos Negro
Summary: This study investigated the adsorption removal of hexavalent chromium (Cr(VI)) from industrial wastewaters using cationic cellulose nanocrystals (CCNC). The results showed that CCNC is capable of rapidly removing Cr(VI) and converting it into less-toxic trivalent species.
Article
Chemistry, Multidisciplinary
Jose Luis Sanchez-Salvador, Mariana P. Marques, Margarida S. C. A. Brito, Carlos Negro, Maria Concepcion Monte, Yaidelin A. Manrique, Ricardo J. Santos, Angeles Blanco
Summary: The world's vegetable supply is more than double its intake, resulting in significant waste. This study investigates the production of lignocellulose micro- and nanofibrils (LCMNF) from greengrocery waste without cellulose extraction. The researchers achieved highly concentrated suspensions without the use of chemicals, offering a novel method to utilize vegetable waste for high-value applications.
Article
Biotechnology & Applied Microbiology
Itziar A. A. Escanciano, Miguel Ladero, Victoria E. E. Santos, Angeles Blanco
Summary: This study focuses on the production of succinic acid (SA) by Actinobacillus succinogenes DSM 22257 from glucose. A simple kinetic model is developed to study the evolution of the process over time. Experimental data shows that operational variables such as initial biomass concentration, yeast extract concentration, agitation speed, and carbon dioxide flow rate significantly affect SA production. The kinetic model is able to accurately fit the experimental data and shed light on the effect of different operational conditions on SA production.
FERMENTATION-BASEL
(2023)
Article
Polymer Science
Francisco de Borja Ojembarrena, Sergio Garcia, Noemi Merayo, Angeles Blanco, Carlos Negro
Summary: This study focuses on the synthesis and characterization of BC membranes, and their application to remove Ni(II) and Pb(II) from wastewater. It was found that BC membranes have excellent adsorption properties for both metals, with Ni(II) removal mechanism involving crystallization and Pb(II) removal being driven by the adsorption process.
Article
Chemistry, Multidisciplinary
Carlos Negro, Gunilla Pettersson, Amanda Mattsson, Staffan Nystroem, Jose Luis Sanchez-Salvador, Angeles Blanco, Per Engstrand
Summary: This study aims to assess the synergic effects of nanocellulose as a bulk additive and hot-pressing technology on the strength and barrier properties of high-yield pulps in packaging. The combination of nanocellulose and hot-pressing improves dry strength by 118%, with individual improvements of 31% by nanocellulose and 92% by hot-pressing. Hot-pressing and fibrillated cellulose also greatly decrease air permeability and increase the paper's ability to withstand compressive forces.
Article
Biochemistry & Molecular Biology
Francisco Rodriguez-Esparragon, Laura B. Torres-Mata, Sara E. Cazorla-Rivero, Jaime A. Serna Gomez, Jesus M. Gonzalez Martin, Angeles Canovas-Molina, Jose A. Medina-Suarez, Ayose N. Gonzalez-Hernandez, Lidia Estupinan-Quintana, Maria C. Bartolome-Duran, Jose C. Rodriguez-Perez, Bernardino Clavo Varas
Summary: ANRIL, a long non-coding RNA, regulates genes associated with atherosclerosis development. Its expression is associated with coronary artery disease, cardiovascular risk factors, and mortality risk.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Jose Medina-Suarez, Francisco Rodriguez-Esparragon, Coralia Sosa-Perez, Sara Cazorla-Rivero, Laura B. Torres-Mata, Aruma Jimenez-O'Shanahan, Bernardino Clavo, Jesus Morera-Molina
Summary: This review discusses the main genetic single nucleotide polymorphisms (SNPs) associated with delayed cerebral ischemia (DCI) and vasospasm, two complications of subarachnoid hemorrhages (SAHs). SNPs of eNOS, asymmetric dimetilarginine, high-mobility group box 1, haptoglobin, endothelin-1 receptor, and angiotensin-converting enzyme have been found to have a relationship with DCI and/or vasospasm.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)