Identification of a regulatory domain controlling theNppa-Nppbgene cluster during heart development and stress

Investigating the Transcriptional Control of Cardiovascular Development

(2015) I. S. Kathiriya et al.   CIRCULATION RESEARCH

CTCF Binding Polarity Determines Chromatin Looping

(2015) Elzo de Wit et al.   MOLECULAR CELL

EMERGE: a flexible modelling framework to predict genomic regulatory elements from genomic signatures

(2015) Karel van Duijvenboden et al.   NUCLEIC ACIDS RESEARCH

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

Noninvasive and quantitative live imaging reveals a potential stress-responsive enhancer in the failing heart

(2014) Ken Matsuoka et al.   FASEB JOURNAL

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Regulation of expression of atrial and brain natriuretic peptide, biomarkers for heart development and disease

(2013) Irina A. Sergeeva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and disease

(2013) Irina A. Sergeeva et al.   CARDIOVASCULAR RESEARCH

Transcriptional repressors: multifaceted regulators of gene expression

(2013) N. Reynolds et al.   DEVELOPMENT

Shadow enhancers flanking the HoxB cluster direct dynamic Hox expression in early heart and endoderm development

(2013) Christof Nolte et al.   DEVELOPMENTAL BIOLOGY

Natriuretic peptide-guided heart failure management

(2013) R. Troughton et al.   EUROPEAN HEART JOURNAL

Identifying multiple causative genes at a single GWAS locus

(2013) M. J. Flister et al.   GENOME RESEARCH

HDAC4 controls histone methylation in response to elevated cardiac load

(2013) Mathias Hohl et al.   JOURNAL OF CLINICAL INVESTIGATION

BET acetyl-lysine binding proteins control pathological cardiac hypertrophy

(2013) Jessica I. Spiltoir et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Epigenetics and Chromatin Remodeling in Adult Cardiomyopathy

(2013) Salma Awad Mahmoud et al.   JOURNAL OF PATHOLOGY

Topology of mammalian developmental enhancers and their regulatory landscapes

(2013) Wouter de Laat et al.   NATURE

Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data

(2013) Job Dekker et al.   NATURE REVIEWS GENETICS

Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy

(2013) R. Papait et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide Studies of CCCTC-binding Factor (CTCF) and Cohesin Provide Insight into Chromatin Structure and Regulation: FIGURE 1.

(2012) Bum-Kyu Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional Regulation Patterns Revealed by High Resolution Chromatin Immunoprecipitation during Cardiac Hypertrophy

(2012) Danish Sayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The long-range interaction landscape of gene promoters

(2012) Amartya Sanyal et al.   NATURE

Topological domains in mammalian genomes identified by analysis of chromatin interactions

(2012) Jesse R. Dixon et al.   NATURE

Robust 4C-seq data analysis to screen for regulatory DNA interactions

(2012) Harmen J G van de Werken et al.   NATURE METHODS

An encyclopedia of mouse DNA elements (Mouse ENCODE)

(2012) et al.   GENOME BIOLOGY

Atrial natriuretic factor in the developing heart: a signpost for cardiac morphogenesis

(2011) Benoit G. Bruneau   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster

(2011) F. Del Greco M. et al.   HUMAN MOLECULAR GENETICS

Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis

(2011) Elza D. van Deel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential Role of Nkx2-5 in Activation of the Atrial Natriuretic Factor Gene in the Developing versus Failing Heart

(2011) S. A. Warren et al.   MOLECULAR AND CELLULAR BIOLOGY

An evolutionarily conserved three-dimensional structure in the vertebrate Irx clusters facilitates enhancer sharing and coregulation

(2011) Juan J. Tena et al.   Nature Communications

Ginseng Inhibits Cardiomyocyte Hypertrophy and Heart Failure via NHE-1 Inhibition and Attenuation of Calcineurin Activation

(2010) Juan Guo et al.   Circulation-Heart Failure

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology

(2009) Marieke Simonis et al.   NATURE METHODS

Distinct Regulation of Developmental and Heart Disease–Induced Atrial Natriuretic Factor Expression by Two Separate Distal Sequences

(2008) Thomas Horsthuis et al.   CIRCULATION RESEARCH