Circadian clock effects on cellular proliferation: Insights from theory and experiments

Amplitude Effects Allow Short Jet Lags and Large Seasonal Phase Shifts in Minimal Clock Models

(2020) Bharath Ananthasubramaniam et al.   JOURNAL OF MOLECULAR BIOLOGY

Development of the Circadian Core Machinery in Mammals

(2020) Yasuhiro Umemura et al.   JOURNAL OF MOLECULAR BIOLOGY

Circadian Regulation in Tissue Regeneration

(2019) Ellen Paatela et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment

(2019) Yool Lee et al.   PLOS BIOLOGY

BMAL1-Driven Tissue Clocks Respond Independently to Light to Maintain Homeostasis

(2019) Patrick-Simon Welz et al.   CELL

Defining the Independence of the Liver Circadian Clock

(2019) Kevin B. Koronowski et al.   CELL

Robust synchronization of the cell cycle and the circadian clock through bidirectional coupling

(2019) Jie Yan et al.   Journal of the Royal Society Interface

Low-dimensional dynamics of two coupled biological oscillators

(2019) Colas Droin et al.   Nature Physics

Dosing time matters

(2019) Marc D. Ruben et al.   SCIENCE

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock

(2019) Zhen Dong et al.   Cancer Discovery

Core Concept: Emerging science of chronotherapy offers big opportunities to optimize drug delivery

(2019) David Adam   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcription-based circadian mechanism controls the duration of molecular clock states in response to signaling inputs

(2019) Sofia Almeida et al.   JOURNAL OF THEORETICAL BIOLOGY

Circadian Clock Synchronization of the Cell Cycle in Zebrafish Occurs through a Gating Mechanism Rather Than a Period-phase Locking Process

(2018) Ricardo Laranjeiro et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA

(2018) David G. Welkie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Cogs: Interplay between Circadian Clock and Cell Cycle

(2018) Jonathan Gaucher et al.   TRENDS IN CELL BIOLOGY

The choroid plexus is an important circadian clock component

(2018) Jihwan Myung et al.   Nature Communications

High-accuracy determination of internal circadian time from a single blood sample

(2018) Nicole Wittenbrink et al.   JOURNAL OF CLINICAL INVESTIGATION

Deciphering the Dynamics of Interlocked Feedback Loops in a Model of the Mammalian Circadian Clock

(2018) Dorjsuren Battogtokh et al.   BIOPHYSICAL JOURNAL

The positive circadian regulators CLOCK and BMAL1 control G2/M cell cycle transition through Cyclin B1

(2018) Elham Farshadi et al.   CELL CYCLE

Cell size control driven by the circadian clock and environment in cyanobacteria

(2018) Bruno M. C. Martins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

(2018) Shaon Chakrabarti et al.   Nature Communications

Circadian Clock, Cell Division, and Cancer: From Molecules to Organism

(2017) Anton Shostak   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Measuring Relative Coupling Strength in Circadian Systems

(2017) Christoph Schmal et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Systems Chronotherapeutics

(2017) Annabelle Ballesta et al.   PHARMACOLOGICAL REVIEWS

Rapid resetting of human peripheral clocks by phototherapy during simulated night shift work

(2017) Marc Cuesta et al.   Scientific Reports

Blood transcriptome based biomarkers for human circadian phase

(2017) Emma E Laing et al.   eLife

What time is it? Deep learning approaches for circadian rhythms

(2016) Forest Agostinelli et al.   BIOINFORMATICS

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation

(2016) Xuan Zhao et al.   CELL

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

(2016) Rishi V. Puram et al.   CELL

Introduction to the Analysis of Survival Data in the Presence of Competing Risks

(2016) Peter C. Austin et al.   CIRCULATION

Intercellular Coupling of the Cell Cycle and Circadian Clock in Adult Stem Cell Culture

(2016) Toru Matsu-ura et al.   MOLECULAR CELL

Transcriptional architecture of the mammalian circadian clock

(2016) Joseph S. Takahashi   NATURE REVIEWS GENETICS

ZeitZeiger: supervised learning for high-dimensional data from an oscillatory system

(2016) Jacob J. Hughey et al.   NUCLEIC ACIDS RESEARCH

Circadian time signatures of fitness and disease

(2016) Joseph Bass et al.   SCIENCE

MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation

(2016) Anton Shostak et al.   Nature Communications

MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells

(2015) Brian J. Altman et al.   Cell Metabolism

Lineage correlations of single cell division time as a probe of cell-cycle dynamics

(2015) Oded Sandler et al.   NATURE

Metabolic and Nontranscriptional Circadian Clocks: Eukaryotes

(2014) Akhilesh B. Reddy et al.   Annual Review of Biochemistry

Modeling circadian clock–cell cycle interaction effects on cell population growth rates

(2014) R. El Cheikh et al.   JOURNAL OF THEORETICAL BIOLOGY

The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells

(2014) Tetsuya Gotoh et al.   MOLECULAR BIOLOGY OF THE CELL

Robust synchronization of coupled circadian and cell cycle oscillators in single mammalian cells

(2014) J. Bieler et al.   Molecular Systems Biology

Phase locking and multiple oscillating attractors for the coupled mammalian clock and cell cycle

(2014) Céline Feillet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ras-Mediated Deregulation of the Circadian Clock in Cancer

(2014) Angela Relógio et al.   PLoS Genetics

Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice

(2013) Ayaka Iwamoto et al.   CHRONOBIOLOGY INTERNATIONAL

The Circadian Molecular Clock Regulates Adult Hippocampal Neurogenesis by Controlling the Timing of Cell-Cycle Entry and Exit

(2013) Pascale Bouchard-Cannon et al.   Cell Reports

Toward the Beginning of Time: Circadian Rhythms in Metabolism Precede Rhythms in Clock Gene Expression in Mouse Embryonic Stem Cells

(2012) Jiffin K. Paulose et al.   PLoS One

NONO couples the circadian clock to the cell cycle

(2012) E. Kowalska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Entrainment of the Mammalian Cell Cycle by the Circadian Clock: Modeling Two Coupled Cellular Rhythms

(2012) Claude Gérard et al.   PLoS Computational Biology

Circadian desynchronization

(2011) A. E. Granada et al.   Interface Focus

Circadian Gating of the Cell Cycle Revealed in Single Cyanobacterial Cells

(2010) Q. Yang et al.   SCIENCE

Design principles of biochemical oscillators

(2008) Béla Novák et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY